教科书结果有助于老年食管鳞状细胞癌患者的长期预后

IF 2.9 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Annals of Gastroenterological Surgery Pub Date : 2024-03-26 DOI:10.1002/ags3.12799

Chihiro Matsumoto, Masaaki Iwatsuki, Chishou Mitsuura, Atsushi Morito, Yuto Maeda, Tasuku Toihata, Keisuke Kosumi, Yoshifumi Baba, Naoya Yoshida, Hideo Baba

{"title":"教科书结果有助于老年食管鳞状细胞癌患者的长期预后","authors":"Chihiro Matsumoto, Masaaki Iwatsuki, Chishou Mitsuura, Atsushi Morito, Yuto Maeda, Tasuku Toihata, Keisuke Kosumi, Yoshifumi Baba, Naoya Yoshida, Hideo Baba","doi":"10.1002/ags3.12799","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>Textbook outcome (TO) is a composite quality measurement of outcomes for evaluating surgical procedures. We investigated whether TO can be used to predict outcomes after curative resection for esophageal squamous cell carcinoma (ESCC) in elderly patients.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>We retrospectively analyzed 105 patients who underwent curative esophagectomy for ESCC from 2005 to 2020. In accordance with previous reports, TO consisted of 10 parameters. The patients were divided into two groups: those who achieved TO (TO) and those who failed to achieve TO (non-TO). We evaluated the association between TO and long-term survival.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>TO was achieved in 28 (26%) patients. The patients in the TO group were significantly older (<i>p</i> = 0.02). The parameter with the lowest achievement rate was “No hospital stay ≥21 days”. The patients in non-TO group had significantly shorter overall survival than those in TO group (<i>p</i> = 0.03). Multivariable Cox regression analyses of overall survival revealed that lymph node metastasis (hazard ratio [HR], 3.42; 95% confidence interval [CI], 1.73–6.78; <i>p</i> < 0.0002) and non-TO (HR, 2.37; 95% CI, 1.05–5.65; <i>p</i> = 0.03) were significantly associated with poor overall survival.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>TO can be used to predict outcomes after curative esophagectomy in elderly patients with ESCC.</p>\n </section>\n </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ags3.12799","citationCount":"0","resultStr":"{\"title\":\"Textbook outcome contributes to long-term prognosis in elderly patients with esophageal squamous cell carcinoma\",\"authors\":\"Chihiro Matsumoto, Masaaki Iwatsuki, Chishou Mitsuura, Atsushi Morito, Yuto Maeda, Tasuku Toihata, Keisuke Kosumi, Yoshifumi Baba, Naoya Yoshida, Hideo Baba\",\"doi\":\"10.1002/ags3.12799\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>Textbook outcome (TO) is a composite quality measurement of outcomes for evaluating surgical procedures. We investigated whether TO can be used to predict outcomes after curative resection for esophageal squamous cell carcinoma (ESCC) in elderly patients.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>We retrospectively analyzed 105 patients who underwent curative esophagectomy for ESCC from 2005 to 2020. In accordance with previous reports, TO consisted of 10 parameters. The patients were divided into two groups: those who achieved TO (TO) and those who failed to achieve TO (non-TO). We evaluated the association between TO and long-term survival.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>TO was achieved in 28 (26%) patients. The patients in the TO group were significantly older (<i>p</i> = 0.02). The parameter with the lowest achievement rate was “No hospital stay ≥21 days”. The patients in non-TO group had significantly shorter overall survival than those in TO group (<i>p</i> = 0.03). Multivariable Cox regression analyses of overall survival revealed that lymph node metastasis (hazard ratio [HR], 3.42; 95% confidence interval [CI], 1.73–6.78; <i>p</i> < 0.0002) and non-TO (HR, 2.37; 95% CI, 1.05–5.65; <i>p</i> = 0.03) were significantly associated with poor overall survival.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>TO can be used to predict outcomes after curative esophagectomy in elderly patients with ESCC.</p>\\n </section>\\n </div>\",\"PeriodicalId\":8030,\"journal\":{\"name\":\"Annals of Gastroenterological Surgery\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ags3.12799\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Gastroenterological Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ags3.12799\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Gastroenterological Surgery","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ags3.12799","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

教科书结果（TO）是评估外科手术结果的一种综合质量测量方法。我们研究了TO是否可用于预测老年食管鳞状细胞癌（ESCC）根治性切除术后的预后。我们回顾性分析了2005年至2020年期间因ESCC接受食管根治性切除术的105例患者。根据以往的报告，TO 包括 10 个参数。患者被分为两组：达到 TO（TO）和未达到 TO（Non-TO）。我们评估了TO与长期生存之间的关系。TO组患者的年龄明显偏大（P = 0.02）。实现率最低的参数是 "无住院时间≥21 天"。非 TO 组患者的总生存期明显短于 TO 组（P = 0.03）。总生存期的多变量 Cox 回归分析显示，淋巴结转移（危险比 [HR]，3.42；95% 置信区间 [CI]，1.73-6.78；P < 0.0002）和非 TO（HR，2.37；95% CI，1.05-5.65；P = 0.03）与总生存期差显著相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

摘要图片

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Textbook outcome contributes to long-term prognosis in elderly patients with esophageal squamous cell carcinoma

Purpose

Textbook outcome (TO) is a composite quality measurement of outcomes for evaluating surgical procedures. We investigated whether TO can be used to predict outcomes after curative resection for esophageal squamous cell carcinoma (ESCC) in elderly patients.

Methods

We retrospectively analyzed 105 patients who underwent curative esophagectomy for ESCC from 2005 to 2020. In accordance with previous reports, TO consisted of 10 parameters. The patients were divided into two groups: those who achieved TO (TO) and those who failed to achieve TO (non-TO). We evaluated the association between TO and long-term survival.

Results

TO was achieved in 28 (26%) patients. The patients in the TO group were significantly older (p = 0.02). The parameter with the lowest achievement rate was “No hospital stay ≥21 days”. The patients in non-TO group had significantly shorter overall survival than those in TO group (p = 0.03). Multivariable Cox regression analyses of overall survival revealed that lymph node metastasis (hazard ratio [HR], 3.42; 95% confidence interval [CI], 1.73–6.78; p < 0.0002) and non-TO (HR, 2.37; 95% CI, 1.05–5.65; p = 0.03) were significantly associated with poor overall survival.