应用经颅磁刺激治疗残余紧张症

M. A. Kaidan, N. V. Zakharova
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引用次数: 0

摘要

紧张症是精神病患者中常见的一种综合征,20%-43%的病例可确诊为紧张症。紧张症患者的治疗方法仅限于在急性期使用苯二氮卓类药物和电痉挛疗法,抗复发和维持治疗仍是最棘手的问题之一。目前,经颅磁刺激是治疗紧张症的一种很有前景的方法。本研究旨在评估对残留紧张性症状的缓解期精神分裂症患者使用经颅磁刺激脑部方法的可能性。材料和方法通过临床和心理测量方法对50名确诊为精神分裂症且残留紧张性症状的患者进行检查,并将其分为两组(治疗组和对比组),对经颅磁刺激4周的效果进行前瞻性评估。结果对残余紧张症患者左侧DLPFC进行经颅磁刺激TMS被证明是有效和安全的,刺激开始前的精神运动障碍有减轻的趋势,基本认知功能也有所改善。结论在标准精神药物治疗方案的基础上使用 TMS 可以有效纠正精神运动症状。
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Application of Transcranial Magnetic Stimulation for the Treatment of Residual Catatonia
Catatonia is a common syndrome among psychiatric patients, diagnosed in 20-43% of cases. Treatment methods for patients with catatonia are limited to the use of benzodiazepines and ECT in the acute period, and the problem of anti-relapse and maintenance therapy remains one of the most difficult. Currently, transcranial magnetic stimulation is a promising approach in the treatment of catatonia. The purpose of the study was to evaluate the possibility of using the method of transcranial magnetic stimulation of the brain in patients with schizophrenia in remission with residual catatonic symptoms. Material and methods. 50 patients diagnosed with schizophrenia and residual catatonic symptoms were examined by clinical and psychometric methods and divided into 2 groups (therapeutic and comparison groups) to prospectively evaluate the effectiveness of transcranial magnetic stimulation for 4 weeks. Results. Transcranial magnetic stimulation of the DLPFC on the left in patients with residual catatonia TMS turned out to be effective and safe a tendency was revealed to reduce psychomotor impairments that made up the clinical picture before the start of stimulation, along with an improvement in basic cognitive functions. Conclusions. Augmentation of standard psychopharmacotherapy protocols with TMS is effective for the correction of psychomotor symptoms.
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