综述用于靶向特定类型癌症的透明质酸功能化硫氮共掺石墨烯量子点纳米共轭物

IF 3.1 Q2 PHARMACOLOGY & PHARMACY Advanced pharmaceutical bulletin Pub Date : 2024-03-17 DOI:10.34172/apb.2024.043
Kedar Bavaskar, Vinit Patil, Dilip Morani, Ashish Jain
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引用次数: 0

摘要

每年都有许多人死于癌症。随着科学研究的不断深入,疾病、代谢紊乱、高危感染和其他病症的发病率已大大降低。化疗和放疗仍然是癌症患者的首选治疗方法,此外还有手术切除肿瘤。由于药物经常具有严重的全身毒性和不良的药代动力学,并且仍然无法以有效浓度到达肿瘤部位,因此化疗方法已经进行了修改。现在,借助纳米技术,化疗可以更加安全有效地进行。基于纳米技术的石墨烯量子点因其物理和化学性质、毒性小、体积小、荧光性好、给药效果好等特点,在乳腺癌检测、给药系统和乳腺癌治疗中非常适用。本文分析了石墨烯量子点作为生物技术和纳米医学的前沿平台及其在癌症给药中的应用。研究表明,石墨烯量子点可与透明质酸有效共轭,实现高效的靶向给药。
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Review on Hyaluronic Acid Functionalized Sulfur and Nitrogen Co-Doped Graphene Quantum Dots Nano Conjugates for Targeting of Specific type of Cancer.
Many people lose their lives to cancer each year. The prevalence of illnesses, metabolic disorders, high-risk infections, and other conditions has been greatly slowed down by expanding scientific research. Chemotherapy and radiation are still the initial lines of treatment for cancer patients, along with surgical removal of tumors. Modifications have been made in chemotherapy since medicines frequently have substantial systemic toxicity and poor pharmacokinetics and still do not reach the tumor site at effective concentrations. Chemotherapy may now be administered more safely and effectively thanks to nanotechnology. Nanotechnology-based graphene quantum dots are very applicable in breast cancer detection, as a drug delivery system, and in the treatment of breast cancer because of their physical and chemical properties, less toxicity, small size, fluorescence, and effective drug delivery. This paper analyzes the graphene quantum dots as cutting-edge platforms for biotechnology and nanomedicine also its application in drug delivery in cancer. It shows that graphene quantum dots can be effectively conjugated with Hyaluronic Acid to achieve efficient and target-specific delivery.
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来源期刊
Advanced pharmaceutical bulletin
Advanced pharmaceutical bulletin PHARMACOLOGY & PHARMACY-
CiteScore
6.80
自引率
2.80%
发文量
51
审稿时长
12 weeks
期刊最新文献
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