Recurrent conjunctival papilloma: Case report

Papilloma is a histopathological term describing specific morphology of tumors. Conjunctival papilloma is a benign growth that arises from the stratified squamous epithelium of the conjunctiva. Two cases of recurrent conjunctival papilloma who were operated and adjunctive therapy given are presented here. Both the cases had history of recurrence of conjunctival papilloma following excision. The extent of papilloma was different in both the cases. One case has minimal symptoms and lesion the inferior quadrant while the other was symptomatic in form of diminution of vision, watering, forgien body sensation, photophobia and blepharospasm with alesion extending 270 degrees of limbal area and covering whole of the cornea. The management was same in both the cases : excisional biopsy in both the eyes under local anaesthesia, intraoperative crotherapy and use of mitomycin C and post operative use of chloramphenicol and mitomycin c eye drops. Various treatment modalities have been described for management of conjunctival papilloma. These comprise conservative management, topical use of interferon alpha 2b, excisional biopsy and use of adjunctive treatment such as carbon dioxide laser, cryoablation and application of mitomycin C to prevent recurrence. This patient was managed with excisional biopsy along with adjunctive treatment in form of cryoablation and mitomycin c application to prevent recurrence.