{"title":"姜黄素和槲皮素在 MCF-7 细胞系中的细胞毒性评估","authors":"Devi Senthil, Venkateswaran Velliyagounder, Lakshmi Kanakaraj","doi":"10.30574/wjbphs.2024.17.2.0048","DOIUrl":null,"url":null,"abstract":"Cytotoxic evaluation of Curcumin and Quercetin in MCF-7 cell lines was performed to assess their potential anticancer activity. MCF-7 is a widely used breast cancer cell line, and evaluating the cytotoxic effects of the compounds on these cells can provide valuable information about their potential as an anticancer agent. Curcumin, a naturally occurring compound found in turmeric, has been extensively studied for its potential anticancer properties, including its effects on MCF-7 cell lines. MCF-7 cells are commonly used as a model for studying breast cancer. Quercetin, a flavonoid found in various fruits, vegetables, and plant-based foods, has also been studied for its potential anticancer effects, including its effects on MCF-7 cell lines. The combination of curcumin and quercetin has been investigated for its potential synergistic effects on MCF-7 cell lines, aiming to enhance the anticancer activity of both compounds. The synergistic effects observed in the combination of curcumin and quercetin on MCF-7 cells suggests that the compounds may act through complementary mechanisms, enhancing their individual anticancer activities.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"16 12","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cytotoxic evaluation of curcumin and quercetin in MCF-7 cell lines\",\"authors\":\"Devi Senthil, Venkateswaran Velliyagounder, Lakshmi Kanakaraj\",\"doi\":\"10.30574/wjbphs.2024.17.2.0048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cytotoxic evaluation of Curcumin and Quercetin in MCF-7 cell lines was performed to assess their potential anticancer activity. MCF-7 is a widely used breast cancer cell line, and evaluating the cytotoxic effects of the compounds on these cells can provide valuable information about their potential as an anticancer agent. Curcumin, a naturally occurring compound found in turmeric, has been extensively studied for its potential anticancer properties, including its effects on MCF-7 cell lines. MCF-7 cells are commonly used as a model for studying breast cancer. Quercetin, a flavonoid found in various fruits, vegetables, and plant-based foods, has also been studied for its potential anticancer effects, including its effects on MCF-7 cell lines. The combination of curcumin and quercetin has been investigated for its potential synergistic effects on MCF-7 cell lines, aiming to enhance the anticancer activity of both compounds. The synergistic effects observed in the combination of curcumin and quercetin on MCF-7 cells suggests that the compounds may act through complementary mechanisms, enhancing their individual anticancer activities.\",\"PeriodicalId\":23738,\"journal\":{\"name\":\"World Journal of Biology Pharmacy and Health Sciences\",\"volume\":\"16 12\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Biology Pharmacy and Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30574/wjbphs.2024.17.2.0048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Biology Pharmacy and Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30574/wjbphs.2024.17.2.0048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cytotoxic evaluation of curcumin and quercetin in MCF-7 cell lines
Cytotoxic evaluation of Curcumin and Quercetin in MCF-7 cell lines was performed to assess their potential anticancer activity. MCF-7 is a widely used breast cancer cell line, and evaluating the cytotoxic effects of the compounds on these cells can provide valuable information about their potential as an anticancer agent. Curcumin, a naturally occurring compound found in turmeric, has been extensively studied for its potential anticancer properties, including its effects on MCF-7 cell lines. MCF-7 cells are commonly used as a model for studying breast cancer. Quercetin, a flavonoid found in various fruits, vegetables, and plant-based foods, has also been studied for its potential anticancer effects, including its effects on MCF-7 cell lines. The combination of curcumin and quercetin has been investigated for its potential synergistic effects on MCF-7 cell lines, aiming to enhance the anticancer activity of both compounds. The synergistic effects observed in the combination of curcumin and quercetin on MCF-7 cells suggests that the compounds may act through complementary mechanisms, enhancing their individual anticancer activities.