洞察乳腺癌的草药干预:综合评述

Nishi Shukla, S. Usmani, Sahabjada Siddiqui, Om Prakash, S. Wahab, Shabana Khatoon
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引用次数: 0

摘要

目前迫切需要针对乳腺癌等威胁生命的疾病的新疗法,以减轻与之相关的日益沉重的死亡率负担。与现有的化疗或辅助治疗方法相比,赋予生命的天然产品毒性较小,这是它们的一大特点。在我们的综述中,我们试图通过各种体外和体内技术,对草药提取物和生物活性物质的现有数据进行汇编。我们努力积累数据,通过真实记录中的相关关键词进行检索,以进行严谨的文献综述。主要关键词包括草本植物提取物和生物活性物质。主要关键词包括草药提取物、体外、抗癌和转移。全面的探索揭示了一种抗各种组织恶性肿瘤的拮抗剂,但我们把重点放在了乳腺癌细胞系上。尽管如此,有关草药替代品及其生物活性机制的广泛报道,对挖掘其作为标准化疗法的潜力仍具有重要意义。科学证据、相关性和适当的安全性数据可为癌症治疗中的干预措施提供依据。
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An Insight into Herbal Interventions for Breast Cancer: A Comprehensive Review
New therapies for life-threatening ailments like breast carcinoma are urgently required to relieve the ever-increasing burden of the mortality associated with it. The very specific feature associated with life-giving natural products is their lesser toxicity concerning existing strategies viz chemotherapy or adjuvant modalities. In our review, we have tried to compile the existing data on exploring herbal extracts and bio-actives through various in vitro and in vivo techniques. An attempt has been made to accumulate data for a scrupulous literature review retrieved via pertinent keywords in authentic records. Web of Science, Scopus, and Science Direct. The major keywords included herbal extract, in vitro, anticancer, and metastasis. A comprehensive exploration unveiled an imperative role against malignancies of various tissues, but we focussed on breast cancer cell lines. Still, extensive reports on herbal alternatives and their bio-active mechanism are highly implicated in tapping their potential as standardized regimens. Scientific evidence, correlations, and proper safety data may substantiate interventions in cancer therapy.
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