全面回顾化学在医学和医疗技术中的应用

Ayesha Rafique, Ayesha Saddiqa, Aqsa Ashfaq, Haiqa Akmal, Rabia Mehvish, Sarmad Yousaf, Rahila Yasmeen, Amina Akram, Muhammad Kaleem Ullah
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引用次数: 0

摘要

药物化学扎根于化学,同时融合了生物、医学和制药科学的元素,在分子水平上引领着疾病诊断、治疗和预防的创新。化学是理解药物与生物系统之间错综复杂的相互作用的基石,指导着药物化学家精确设计和合成具有特定活性和优化治疗效果的化合物。与此同时,建立在化学原理基础上的纳米技术为先进成像、诊断、治疗平台和给药系统提供了前景广阔的途径。聚合物是整形外科和心血管设备等医疗应用领域不可或缺的材料,它推动了医疗技术的进步,进一步凸显了化学不可或缺的作用。分析化学技术在药物分析和生物标记物鉴定中发挥着关键作用,为这些工作提供了重要支持。此外,放射性金属离子在核医学的治疗和诊断中发挥着关键作用,创新的 DOTA-TATE 化合物就是证明。这些跨学科的进步凸显了化学在现代医疗保健系统中促进创新和提高患者护理标准的关键作用。
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A Comprehensive Review on Chemistry Uses in Medicine and Medical Technology
Medicinal chemistry, firmly rooted in chemistry while incorporating elements of biological, medical, and pharmaceutical sciences, spearheads innovation in disease diagnosis, treatment, and prevention at the molecular level. Chemistry serves as a cornerstone for understanding the intricate interactions between medications and biological systems, guiding medicinal chemists in the precise design and synthesis of compounds tailored for specific activities and optimized therapeutic outcomes. Concurrently, nanotechnology, founded on chemical principles, presents promising avenues in advanced imaging, diagnostics, theranostic platforms, and drug delivery systems. The indispensable role of chemistry is further underscored by polymers, integral to medical applications such as orthopedics and cardiovascular devices, driving forward medical advancements. Analytical chemistry techniques play a critical role in drug analysis and biomarker identification, providing essential support for these endeavors. Additionally, radioactive metal ions play pivotal roles in therapy and diagnosis within nuclear medicine, as demonstrated by the innovative DOTA-TATE compound. These interdisciplinary advancements underscore the crucial role of chemistry in fostering innovation and elevating patient care standards within modern healthcare systems.
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