Roemani Muhammadiyah 医院用于评估支气管肺炎儿科抗生素使用情况的解剖治疗化学/定义每日剂量

Rissa Maharani Dewi, Nanda Maprillia, Nindita Sari Nastiti
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摘要

covid19大流行后,被诊断为支气管肺炎的儿科患者重复住院的人数增加,这是第一位的。治疗管理与住院时间长短有关。小儿支气管肺炎是抗生素治疗的病例。现行指南建议,在对住院儿科患者的肺炎进行抗生素治疗时,应选择一线治疗方案和替代方案。急性感染的经验性广谱抗生素治疗,考虑可能涉及肺炎球菌的常见病因 抗生素的大量使用会增加耐药性的风险。本研究采用观察描述性设计,从 280 例儿科患者样本中收集回顾性数据,旨在评估 ATC/DDD 法使用抗生素的情况。根据经验性选择疗法 DDD(定义日剂量)/100 患者日,广泛使用的抗生素数量为头孢曲松 38.36 DDD /100 患者日,其次是头孢哌酮舒巴坦 3.88 DDD /100 患者日、头孢他啶 3.70 DDD /100 病人日,阿奇霉素 0.76 DDD /100 病人日,氨苄西林舒巴坦 0.50 DDD /100 病人日,头孢克肟 0.27 DDD /100 病人日,美罗培南 0.13 DDD /100 病人日。DU90% 包括的药物数据有头孢曲松、头孢哌酮舒巴坦、头孢他啶。从研究结果来看,头孢曲松的 DDD/100 病人日值最高。DDD 值表明抗生素使用量大,但并不意味着不合理用药,因此必须进行定性审查。
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Anatomical Therapeutic Chemical / Define Daily Dose for evaluation of bronchopneumonia pediatric antibiotics use at Roemani Muhammadiyah Hospital
The increase in repeat hospitalizations after the covid19 pandemic with bronchopneumonia diagnoses in pediatric patients is the first rank. Therapeutic management was associated with the length of hospitalization. Pediatric bronchopneumonia is the case with antibiotic therapy. Current guidelines recommend first-line and alternative options in the management of antibiotic therapy for pneumonia in hospitalized pediatric patients. Empirical broad-spectrum antibiotic therapy for acute infections with consideration of the common etiology of possible pneumococcal involvement The risk of resistance increases with the massive use of antibiotics. The study had an observational descriptive design with retrospective data collection from 280 samples of pediatric patients, aiming to evaluate the use of antibiotics with the ATC/DDD method. Based on empirical selected therapy DDD (Define Daily Dose)/100 patient days, the quantity of antibiotics that are widely used is ceftriaxon 38.36 DDD /100 patient days followed by Cefoperazon sulbactam 3.88 DDD /100 patient days, Cefotaxime 3.77 DDD /100 patient days, Gentamicin 2.57 DDD /100 patient days, Amikacin 1. 70 DDD /100 patient days, Azithromycin 0.76 DDD /100 patient days, Ampicillin Sulbactam 0.50 DDD /100 patient days, Cefixime 0.27 DDD /100 patient days, and Meropenem 0.13 DDD /100 patient days. Drug data included in DU90% are Ceftriaxon, Cefoperzon Sulbactam, Cefotaxime. From the research conducted, the highest DDD/100 patient days value was Ceftriaxon. DDD value indicates high use of antibiotics, does not mean unreasonable use of drugs, so a qualitative review must be done.
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