目前对多发性硬化症的认识

Avi Choudhary, Himani Kaushik
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引用次数: 0

摘要

多发性硬化症是一种慢性中枢神经系统脱髓鞘疾病。多发性硬化症在不同人群中的发病率各不相同。多发性硬化症的确切病因尚不清楚。多发性硬化症神经组织破坏的病理生理学原理是神经元、神经胶质细胞和免疫系统之间复杂的相互作用。多发性硬化症的症状多种多样,包括无力、痉挛、步态和平衡问题、尿失禁、姿势摇摆、构音障碍<吞咽困难和感觉缺失等。改变病情的药物是多发性硬化症的长期治疗方法,但不能治愈疾病本身,只能帮助减缓病情发展,防止新的发作、症状are-ups,并延缓疾病的进展。这些药物可以减轻神经,控制。康复团队与患者及其家人在身体和社会心理方面开展合作,以提高患者的生活质量。定期和精心策划的物理治疗计划有助于增强患者的稳定性,在适当的药物治疗下,经过一段时间后,患者的稳定性会得到改善,复发次数也会持续减少。应采用精心设计的康复计划和必要的预防措施来改善患者的整体状况。
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CURRENT UNDERSTANDING OF MULTIPLE SCLEROSIS
Multiple Sclerosis is a chronic demyelinating disorder of Central Nervous System. Frequency of MS varies in different populations. The precise cause of MS is still unknown. Pathophysiology of neurological tissue destruction in Multiple Sclerosis results from a complex interaction between the neurons, glia and immune system. There is a wide range of symptoms seen in MS including weakness, spasticity, gait and balance problems, urinary incontinence, postural sway, dysarthria< dysphagia and sensory loss etc. Disease-modifying drugs are the long-term treatment for MS but cannot cure the disease itself but only aid in slowing the progression and preventing new attacks, symptom are-ups and delay the advance of the disease. These may reduce nerve inammation and manage the are-ups. The rehabilitation team works with patients and their family on physical and psychosocial aspects in order to promote a superior QoL. A regular and well planned physiotherapy program helps in increasing stability and with appropriate drug treatment, over a period of about time leads to an improvement in stability along with a consecutive decrease in the relapse number. A well designed rehabilitation program along with necessary precautions should be used to improve the overall conditioning of the patient.
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