使用低强度激光辐射和脂质体软膏治疗冠状病毒感染后患者的炎症性牙周病

L. S. Kruglova, A. S. Romashchenko
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摘要

一些学者提出了一个假设,即 COVID-19 所特有的全身亚临床血管炎症在这种感染的外周并发症(包括口腔并发症)的发生中扮演了重要角色。值得注意的是,COVID-19 患者牙龈炎和牙周炎的发病率很高。材料和方法对 35 名被诊断为慢性全身性牙周炎和急性期慢性牙龈炎的患者进行了门诊随访。所有患者在过去的 2 至 6 个月中都曾使用过 COVID-19。患者分为两组:研究组(18 人)和对照组(17 人)。所有患者都接受了专业的口腔卫生治疗。在研究组中,在进行低强度激光治疗的同时,初步涂抹脂质体凝胶。临床研究方法包括采集病史、检查和确定指数(CFE 指数、绿色朱砂指数、PMA 指数、CI 指数、罗素指数)。研究结果。治疗后,研究组所有患者的 CFE 指数均达到 1 级,最高为 4 级(代偿);对照组患者的 CFE 指数为 1-2 级(88.2% 的患者为代偿,11.8% 的患者为亚代偿)。治疗后,两组患者的绿色朱砂指数分别下降了 40.5% 和 31.3%,组间差异不明显。研究组的 PMA 指数下降了 88.8%,对照组下降了 71.5%。研究组的出血指数降低了 86.4%,对照组降低了 60.9%。研究组还考虑了罗素指数,该指数可将牙龈炎的存在、牙齿的活动度和牙周袋的深度考虑在内。研究组的罗素指数降低了 92.3%,对照组降低了 63.8%。研究结论所开发的复合疗法包括低强度激光照射和脂质体凝胶的初步应用,比治疗这种病症的标准方法更有效。
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The use of low-intensity laser radiation and liposomal cream in the treatment of inflammatory periodontal diseases in patients after the coronavirus infection
A number of authors put forward a hypothesis about the role of systemic subclinical vascular inflammation characteristic of COVID-19 in the development of peripheral complications of this infection, including in the oral cavity. Notably, there is a high incidence of gingivitis and periodontitis in patients after COVID-19. Material and methods. 35 patients diagnosed with chronic generalized periodontitis and chronic gingivitis in the acute stage were followed-up on an outpatient basis. All patients had a history of COVID-19 in the past 2 to 6 months. The patients were divided into two groups: the study group (n = 18) and the control group (n = 17). All patients underwent professional oral hygiene. In the study group, low-intensity laser therapy procedures were performed with preliminary application of a liposomal gel. Clinical research methods included taking an anamnesis, examination, and determination of indices (CFE index, Green Vermilion index, PMA index, CI index, Russell’s index). Research results. After therapy, all patients of the study group had grade 1 CFE index up to 4 (compensated); in the patients of the control group, grade 1–2 CFE was determined (compensated — in 88.2 % of the patients and subcompensated — in 11.8 %). After therapy, the Green Vermilion index decreased in both groups by 40.5 % and 31.3 %, with no significant intergroup difference. The PMA index decreased by 88.8 % in the study group and by 71.5 % in the control group. The index of bleeding reduced by 86.4 % in the study group and by 60.9 % in the control group. The Russell’s index, which allows taking into account the presence of gingivitis, tooth mobility, and the depth of the periodontal pocket, was also considered. Its value decreased by 92.3 % in the study group and by 63.8 % in the control group. Conclusions. The developed therapeutic complex, which includes low-intensity laser exposure with preliminary application of the liposomal gel, is more effective than the standard approach to the treatment of this pathology.
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