糖尿病乳头状瘤病:糖尿病的一种罕见眼部表现

Catarina Pestana Aguiar, Jeniffer Domingues Jesus, J. Chibante-Pedro, António Rocha
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引用次数: 0

摘要

糖尿病乳头状病变(DP)是糖尿病的一种罕见眼部表现。确切的病因尚不清楚,但在某些病例中,它可能与血糖水平的快速纠正有关。目前关于使用玻璃体内抗血管内皮生长因子抗体的病例报告有限,而这种抗体在减轻椎间盘肿胀方面具有一定的疗效。在本病例中,我们介绍了一位 80 岁的糖尿病妇女,她在糖尿病视网膜病变(DR)筛查中被诊断为 DP。她的右眼视力(VA)为数指,左眼为 20/160。在眼底镜检查中,观察到双侧出血性视盘水肿以及非增殖性 DR。这种水肿在荧光素血管造影中也很明显,并通过光学相干断层扫描记录下来。脑部计算机断层扫描结果正常。她接受了雷尼珠单抗治疗,视盘水肿和视力明显改善。
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Diabetic papillopathy: A rare ocular manifestation of diabetes mellitus
Diabetic papillopathy (DP) is a rare ocular manifestation of diabetes mellitus. The exact etiology is not well understood, but in some cases, it may be associated with a rapid correction of the blood glucose level. There are limited case reports describing the use of intravitreal anti-vascular endothelial growth factor antibodies which have shown effectiveness in reducing disc swelling. In this case, we present the case of an 80-year-old diabetic woman diagnosed with DP during a diabetic retinopathy (DR) screening. Her visual acuity (VA) was counting fingers on her right eye and 20/160 on her left eye. At the fundoscopy, an exuberant bilateral hemorrhagic disc edema was observed, along with a nonproliferative DR. This edema was also evident in the fluorescein angiography and was documented through the optical coherence tomography. Brain computed tomography normal. She was treated with ranibizumab with significant improvement of the optic disc edema and the VA.
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