体外氧合膜异物继发严重急性溶血:病例报告

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摘要

呼吸衰竭患者使用体外膜肺氧合(ECMO)后,临床疗效明显改善。尽管技术不断进步,但与设备有关的并发症仍时有发生,其中包括因血液流经回路时产生过大的剪切力而继发的溶血。主要原因与离心锥的血栓形成或不适当的高转速(每分钟转数)有关。然而,氧合膜也必须被视为病因之一。我们描述了一例因 SARS-CoV-2 导致严重难治性 ARDS 并需要 ECMO 支持的年轻患者的病例,该患者因膜功能障碍而出现严重急性溶血的早期临床表现。随着病情的好转,溶血也随之缓解,患者的病情也随之好转。
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Hemólisis aguda severa secundaria a cuerpo extraño en la membrana de oxigenación extracorpórea: reporte de caso

The use of extracorporeal membrane oxygenation (ECMO) in patients with respiratory failure has demonstrated improvement in clinical outcomes. Despite technological advances, complications related to the devices occur, including hemolysis secondary to exaggerated shear forces generated by blood flows through the circuit. The main causes are associated with thrombosis of the centrifuge cone or inappropriately high RPM (revolutions per minute). However, the oxygenation membrane must also be considered as an etiological agent. We describe a case of a young patient with severe and refractory ARDS due to SARS-CoV-2 in need of ECMO support, who developed an early clinical picture of severe acute hemolysis due to membrane dysfunction. The hemolysis resolved with its change with subsequent favorable evolution of the patient.

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