使用臭氧消毒的血液透析单位用水的细菌学质量;12 年的经验

IF 0.2 Q4 UROLOGY & NEPHROLOGY Journal of Renal Injury Prevention Pub Date : 2024-01-29 DOI:10.34172/jrip.2023.32154
Nabadwip Pathak, Sujitha Elan, Sheela Devi
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引用次数: 0

摘要

导言:对肾衰竭患者进行血液透析(HD)/血液滤过(HF)治疗需要大量纯水/超纯水。为生产用于血液透析的超纯水/纯净水,非常需要对水处理厂进行常规消毒。据我们所知和所信,这项研究是首次对血液透析设备中的臭氧消毒水平进行评估。目标:本研究在朋迪榭里医学科学研究所(PIMS)的 HD 设备中进行,并检查了处理后产品的细菌学质量。方法和材料:根据臭氧消毒和产品水培养策略,利用医院记录获取产品水培养报告。根据建议的限值对产品水培养分数进行了调查。结果:在 109 份产品水培养报告样本中,108 份(99.1%)符合建议限值。产品水通过无菌熔融营养琼脂法进行培养;在分析后 24-48 小时内获得了令人满意的菌落计数(<100 CFU/mL)。每周通过 0.1 百万分率臭氧剂量对产品水进行净化/消毒,持续 15 分钟。结论在专家监督下,可通过臭氧消毒策略对 HD 设备中的产品水进行净化/消毒。
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Bacteriological quality of water in hemodialysis unit using ozone disinfection; a 12-year experience
Introduction: A substantial quantity of pure/ultrapure water is required to initiate hemodialysis (HD)/hemofiltration (HF) therapy for patients with renal failure. Routine disinfection of the water treatment plant is highly needed to produce ultrapure/pure water for HD. To the best of our knowledge and belief, this study is the first of its type and origin to evaluate ozone disinfection levels in a HD unit. Objectives: This study was conducted in the Pondicherry Institute of Medical Sciences (PIMS) HD unit and examined the treated product’s bacteriological quality. Methods and Materials: The hospital record was utilized to obtain the product water culture reports based on the ozone disinfection and product water culture strategy. The product water culture fraction was investigated in concordance with the recommended limits. Results: Of 109 product water culture report samples, 108 (99.1%) aligned with the recommended limits. The product water was cultured via the sterile molten nutrient agar approach; satisfactory numbers of colony counts (<100 CFU/mL) were obtained within 24–48 hours of analysis. The product water purification/disinfection was undertaken per week via the 0.1 Parts-Per-Million ozone dose, administered consistently for 15 minutes. Conclusion: The purification/disinfection of the product water in a HD unit may be undertaken by expert supervision via the ozone disinfection strategy.
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来源期刊
Journal of Renal Injury Prevention
Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-
CiteScore
1.60
自引率
0.00%
发文量
36
期刊介绍: The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.
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