{"title":"聚乙烯炔类植物化学物质 \"白术素 \"在治疗癌症和其他人类并发症方面的生物潜力和疗效","authors":"D. Patel, K. Patel","doi":"10.2174/0115733947265189231129105327","DOIUrl":null,"url":null,"abstract":"\n\nAtractylodes lancea Thunb. (Asteraceae) is a commonly used medicinal\nplant for gastric and appetite-associated complications in traditional Chinese medicine. The rhizome\nof Atractylodes lancea has been widely used for the treatment of human complications. Atractylodin\nhas anti-angiogenic, anti-cancer, anti-inflammatory, anti-microbial, anti-pyretic and anti-hypertensive\npotential in medicine. Nano-formulations of atractylodin were also prepared in the scientific field\nto enhance its water solubility and efficacy in cholangiocarcinoma.\n\n\n\nHealth-beneficial aspects of atractylodin in medicine have been investigated in the present\nwork through collected scientific information on atractylodin from different literature databases. Scientific\ndata on atractylodin has been collected from Google, Science Direct, Scopus, and PubMed.\nFurther, detailed pharmacological activities and analytical aspects of atractylodin were discussed in\nthis paper in order to know its biological potential in medicine. Analytical techniques of atractylodin\nwere also discussed in the present work for separation, isolation, and identification of atractylodin.\n\n\n\nScientific data analysis signified the biological importance of Atractylodes lancea Thunb.\nand its active phytochemical atractylodin in medicine. Scientific data signified the presence of atractylodin\nin Atractylodes lancea, Atractylodes chinensis, Atractylodes japonica, Atractylodes macrocephala,\nAtractylodes ovate and Atractylodis Rhizoma. Atractylodin has a significant biological\neffect on cholangiocarcinoma, hepatocellular carcinoma, breast cancer, lung cancer, cancer anorexiacachexia\nsyndrome, colitis, rheumatoid arthritis, respiratory complications, GIT complications, hepatic\ncomplications, atopic dermatitis, aging process, neurodegenerative disease, calcified aortic valve\ndisease, hypertension, pulmonary fibrosis, body temperature, olfactory neurons, podocyte hypermotility\nand toxicity. Further, its anti-nociceptive, anti-fibrotic, anti-angiogenic, anti-virulence, antibacterial,\ninsecticidal, lipase inhibitory potential, immunomodulatory, and positive inotropic effects\nwere also discussed in the present paper. Analytical techniques for the separation, isolation and identification\nof atractylodin in different samples were also discussed in the present work.\n\n\n\nThe present work's scientific data signified the biological importance of atractylodin in\nmedicine.\n","PeriodicalId":503819,"journal":{"name":"Current Cancer Therapy Reviews","volume":"11 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biological Potential and Therapeutic Effectiveness of a Polyethylene Alkyne Class Phytochemical ‘Atractylodin’ in Medicine for the Treatment\\nof Cancer and other Human Complications\",\"authors\":\"D. Patel, K. Patel\",\"doi\":\"10.2174/0115733947265189231129105327\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nAtractylodes lancea Thunb. (Asteraceae) is a commonly used medicinal\\nplant for gastric and appetite-associated complications in traditional Chinese medicine. The rhizome\\nof Atractylodes lancea has been widely used for the treatment of human complications. Atractylodin\\nhas anti-angiogenic, anti-cancer, anti-inflammatory, anti-microbial, anti-pyretic and anti-hypertensive\\npotential in medicine. Nano-formulations of atractylodin were also prepared in the scientific field\\nto enhance its water solubility and efficacy in cholangiocarcinoma.\\n\\n\\n\\nHealth-beneficial aspects of atractylodin in medicine have been investigated in the present\\nwork through collected scientific information on atractylodin from different literature databases. Scientific\\ndata on atractylodin has been collected from Google, Science Direct, Scopus, and PubMed.\\nFurther, detailed pharmacological activities and analytical aspects of atractylodin were discussed in\\nthis paper in order to know its biological potential in medicine. Analytical techniques of atractylodin\\nwere also discussed in the present work for separation, isolation, and identification of atractylodin.\\n\\n\\n\\nScientific data analysis signified the biological importance of Atractylodes lancea Thunb.\\nand its active phytochemical atractylodin in medicine. Scientific data signified the presence of atractylodin\\nin Atractylodes lancea, Atractylodes chinensis, Atractylodes japonica, Atractylodes macrocephala,\\nAtractylodes ovate and Atractylodis Rhizoma. Atractylodin has a significant biological\\neffect on cholangiocarcinoma, hepatocellular carcinoma, breast cancer, lung cancer, cancer anorexiacachexia\\nsyndrome, colitis, rheumatoid arthritis, respiratory complications, GIT complications, hepatic\\ncomplications, atopic dermatitis, aging process, neurodegenerative disease, calcified aortic valve\\ndisease, hypertension, pulmonary fibrosis, body temperature, olfactory neurons, podocyte hypermotility\\nand toxicity. Further, its anti-nociceptive, anti-fibrotic, anti-angiogenic, anti-virulence, antibacterial,\\ninsecticidal, lipase inhibitory potential, immunomodulatory, and positive inotropic effects\\nwere also discussed in the present paper. Analytical techniques for the separation, isolation and identification\\nof atractylodin in different samples were also discussed in the present work.\\n\\n\\n\\nThe present work's scientific data signified the biological importance of atractylodin in\\nmedicine.\\n\",\"PeriodicalId\":503819,\"journal\":{\"name\":\"Current Cancer Therapy Reviews\",\"volume\":\"11 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Cancer Therapy Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/0115733947265189231129105327\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cancer Therapy Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115733947265189231129105327","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Biological Potential and Therapeutic Effectiveness of a Polyethylene Alkyne Class Phytochemical ‘Atractylodin’ in Medicine for the Treatment
of Cancer and other Human Complications
Atractylodes lancea Thunb. (Asteraceae) is a commonly used medicinal
plant for gastric and appetite-associated complications in traditional Chinese medicine. The rhizome
of Atractylodes lancea has been widely used for the treatment of human complications. Atractylodin
has anti-angiogenic, anti-cancer, anti-inflammatory, anti-microbial, anti-pyretic and anti-hypertensive
potential in medicine. Nano-formulations of atractylodin were also prepared in the scientific field
to enhance its water solubility and efficacy in cholangiocarcinoma.
Health-beneficial aspects of atractylodin in medicine have been investigated in the present
work through collected scientific information on atractylodin from different literature databases. Scientific
data on atractylodin has been collected from Google, Science Direct, Scopus, and PubMed.
Further, detailed pharmacological activities and analytical aspects of atractylodin were discussed in
this paper in order to know its biological potential in medicine. Analytical techniques of atractylodin
were also discussed in the present work for separation, isolation, and identification of atractylodin.
Scientific data analysis signified the biological importance of Atractylodes lancea Thunb.
and its active phytochemical atractylodin in medicine. Scientific data signified the presence of atractylodin
in Atractylodes lancea, Atractylodes chinensis, Atractylodes japonica, Atractylodes macrocephala,
Atractylodes ovate and Atractylodis Rhizoma. Atractylodin has a significant biological
effect on cholangiocarcinoma, hepatocellular carcinoma, breast cancer, lung cancer, cancer anorexiacachexia
syndrome, colitis, rheumatoid arthritis, respiratory complications, GIT complications, hepatic
complications, atopic dermatitis, aging process, neurodegenerative disease, calcified aortic valve
disease, hypertension, pulmonary fibrosis, body temperature, olfactory neurons, podocyte hypermotility
and toxicity. Further, its anti-nociceptive, anti-fibrotic, anti-angiogenic, anti-virulence, antibacterial,
insecticidal, lipase inhibitory potential, immunomodulatory, and positive inotropic effects
were also discussed in the present paper. Analytical techniques for the separation, isolation and identification
of atractylodin in different samples were also discussed in the present work.
The present work's scientific data signified the biological importance of atractylodin in
medicine.