了解 JN.1 的分子基础

Dr. Raghavendra Rao M. V., Dr. Vijaykumar Chennamchetty, Dr. Pavani G., Dr. Manick Dass, Dr. Srilatha Basetty, Dr. Rajkumar Kudari, Dr. Mahendra Kumar Verma, Dr. Abdur Rahman, Dr. P. Jaganmohan Rao
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摘要

COVID-19 JN.1亚变体最初是在卢森堡发现的,据信与被认为是Omicron亚变体衍生物的Pirola变体(BA 2.86)有关。这就像在走钢丝。地球上到处都是病毒。肺是最重要的呼吸器官。印度 SARS-CoV-2 基因组联盟 (INSACOG) 在喀拉拉邦的监测中发现了 Covid 19 亚变种 JN.1。JN.1 原本是 BA.2.86 系的一部分,现在已被世卫组织认定为一种独特的变种。令人欣慰的是,世卫组织指出,目前的疫苗对 JN.1 和其他流行的 COVID-19 变异株引起的严重疾病和死亡仍然有效。12 月初,美国疾病预防控制中心(CDC)报告说,根据该机构的最新预测,JN.1 亚变异体估计占美国病例的 15%至 29%。据疾病预防控制中心称,JN.1 于 9 月在美国首次被发现。此外,中国报告了 7 例 COVID 亚变异体感染病例。
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UNDERSTANDING THE MOLECULAR BASIS OF JN.1
COVID-19 JN.1,subvariant, was initially identified in Luxembourg and is believed to have a connection to the Pirola variant (BA 2.86), which is considered a derivative of the Omicron subvariant.The new Omicron variant of SARS-cov-2 speeding around the world may bring another wave of chaos. It is like walking on a tightrope. The earth is brimming with viruses. The lungs are the paramount respiratory organs. Covid 19 sub variant JN.1 detected in 79 years old Kerala woman.It has been detected in Kerala amid surveillance led by Indian SARS-CoV-2 Genomic Consortium (INSACOG).Originally part of lineage BA.2.86, JN.1 is now recognized as a distinct variant of interest by the WHO. Reassuringly, WHO states that current vaccines remain effective against severe disease and death caused by JN.1 and other circulating COVID-19 variants. In early December, the CDC, reported that the JN.1 subvariant constitutes an estimated 15% to 29% of cases in the United States, as per the agency's most recent projections. According to the CDC, JN.1 was initially identified in the United States in September. Additionally, China reported seven infections of the COVID subvariant. 
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