运动训练:对慢性阻塞性肺病患者有何影响?

R. Djebaili, B. Chiboub
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摘要

导言运动训练可通过体育锻炼重新激活有氧途径,从而改善慢性阻塞性肺病(COPD)患者的呼吸困难,并打破减重螺旋:筛选出 60 名慢性阻塞性肺病患者,对其进行为期四周的门诊运动训练和肌肉强化训练,每周 3 次,并排除以下情况:有运动训练禁忌症的患者;重症患者或长期接受氧疗的患者。该计划包括在自行车测力计上进行 45 分钟的运动训练、下肢肌肉强化训练和营养监测。营养管理包括根据营养状况安排饮食,以及为营养不良的慢性阻塞性肺病患者开具口服食物补充剂处方。训练前后的评估参数包括生物阻抗分析(BIA)、6MWT、股四头肌等长自主收缩(MVC)和动态耐力以及生活质量问卷(Q11):结果:40 名慢性阻塞性肺病患者(36 名男性和 4 名女性)完成了该项目,年龄为 67.22(± 10)岁。其中 36 人为非吸烟者。10名患者(GOLD I),14名患者(GOLD II),16名患者(GOLD III),无患者(GOLD IV)。呼吸困难程度为 MRC 2 期(± 1)。训练后,股四头肌功能((MVC)和耐力)显著改善(P < 0.0001)。6MWT运动距离的改善也很明显(P < 0.0001)。从 Q11 问卷的总分来看,训练后生活质量明显改善。结论:本研究证实了训练主要对慢性阻塞性肺病患者的肌肉功能、努力能力和生活质量有益。
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Exercise training: which impact on COPD patients?
Introduction: Exercise training reactivates the aerobic pathway through physical exercise, thereby improving dyspnea and breaking deconditioning spiral in chronic obstructive pulmonary disease (COPD) patients. Method: 60 COPD patients were selected to benefit from a four-week outpatient exercise training and muscle strengthening program, at a rate of 3 sessions per week, after excluding the following cases: patients who have contraindications to exercise training; severe patients or those receiving long-term oxygen therapy. The program combined exercise training on a bicycle ergometer for 45 min, muscle strengthening of the lower limbs and nutritional monitoring. Nutritional management included a diet based on nutritional status and the prescription of oral food supplements for malnourished COPD patients. Parameters assessed before and after training were bioimpedance analysis (BIA),6MWT, quadriceps isometric voluntary contraction (MVC) and dynamic endurance, and the quality-of-life questionnaire (Q11). Result: Forty COPD patients (36 men and 4 women) aged 67.22 (± 10) years were able to complete the program. Amid them, 36 were non-smokers. Ten patients (GOLD I), 14 patients (GOLD II), 16 patients (GOLD III), no patients (GOLD IV). Dyspnea was stage 2 (± 1) m MRC. After training, quadriceps muscle function ((MVC) and endurance) improved significantly (p < 0.0001). The improvement in distance covered during 6MWT was also significant (p < 0.0001). A significant improvement in quality of life after training was noted on the total score of the Q11 questionnaire. No significant improvement in body composition after training in COPD patients. Conclusion: this study has confirmed the beneficial effects of training mainly on muscle function, effort capacity and quality of life in COPD patients.
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