与人类 T 细胞淋巴细胞病毒 1 型有关的葡萄膜炎,病例回顾

Margarida Baptista, C. Bruxelas, Miguel Cordeiro, Marta Guedes
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引用次数: 0

摘要

人类 T 细胞淋巴细胞病毒 1 型(HTLV-1)是一种地方性逆转录病毒,与成人 T 细胞白血病/淋巴瘤(ATL)、HTLV-1 相关骨髓病/热带痉挛性截瘫(HAM-TSP)和 HTLV-1 葡萄膜炎(HU)有关。后者可能与 HAM-TSP 同时出现,但很少与 ATL 同时出现,也可能是病毒感染的一种独立表现。作者通过一个临床病例回顾了有关 HU 的文献。作者在 MEDLINE 数据库(PubMed)中进行了文献检索,并纳入了 2022 年之前完成的调查。由于人口迁移,HU 在非流行的大都市地区的流行率正在上升,因此它正日益成为葡萄膜炎患者鉴别诊断中的重要病原体。
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Human T-cell lymphotropic virus type 1-related uveitis, review about a case
Human T-cell lymphotropic virus type 1 (HTLV-1) is an endemic retrovirus associated with adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM-TSP), and HTLV-1 uveitis (HU). The latter may occur in association with HAM-TSP, more rarely along ATL, or as an isolated manifestation of the viral infection. The authors present a review of the literature on HU, illustrated by a clinical case. A literature search was performed in the MEDLINE database (PubMed) and included surveys completed until 2022. HU prevalence is increasing in nonendemic metropolitan areas due to migration, thus it is becoming an increasingly relevant agent in the differential diagnosis of patients with uveitis.
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