对接受前列腺癌根治术的局部晚期前列腺癌患者进行新辅助化学激素疗法与激素疗法对比的前瞻性随机试验。

The Journal of Urology Pub Date : 2024-04-09 DOI:10.1097/ju.0000000000003876

Hongyang Qian, Chenfei Chi, Thibault Tricard, Yinjie Zhu, Liang Dong, Yanqing Wang, Jianjun Sha, Jiayi Wang, Zehua Ma, Yan Wang, Jiazhou Liu, Baijun Dong, Jiahua Pan, Wei Xue

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引用次数: 0

摘要

在根治性前列腺切除术（RP）前进行基于多西他赛的新辅助化疗（NCHT）的益处在很大程度上仍不为人所知。我们探讨了基于多西他赛的新辅助化疗（NCHT）与新辅助激素治疗（NHT）相比，是否能为局部晚期前列腺癌患者带来病理益处并改善无生化进展生存期（bPFS）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Prospective Randomized Trial of Neoadjuvant Chemohormonal Therapy vs Hormonal Therapy in Locally Advanced Prostate Cancer Treated by Radical Prostatectomy.

Benefits of docetaxel-based neoadjuvant chemohormonal therapy (NCHT) before radical prostatectomy (RP) remain largely unknown. We explored whether docetaxel-based NCHT would bring pathological benefits and improve biochemical progression-free survival (bPFS) over neoadjuvant hormonal therapy (NHT) in locally advanced prostate cancer.

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The Journal of Urology

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