Eleanor L.S. Leavens , Leah M. Lambart , Gideon St.Helen , Neal L. Benowitz , Matthew S. Mayo , Kazi M. Farhad Mahmud , Michael J. Arnold , Nicole L. Nollen
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No known research has directly examined the impact of menthol vs. tobacco flavored e-liquid use on acute e-cigarette use patterns, subjective experience, behavioral intentions, and craving and withdrawal among menthol cigarette smokers.</p></div><div><h3>Methods</h3><p>Black (<em>n</em> = 47) and White (<em>n</em> = 4) nicotine-deprived menthol smokers with limited e-cigarette experience completed two counterbalanced in-laboratory 30-minute ad libitum vaping sessions with menthol and tobacco nicotine salt-based e-liquid in a randomized crossover pilot trial design. Questionnaires assessed reductions in craving and withdrawal and post-session subjective experience and behavioral intentions. Puff topography was measured continuously throughout each vaping session.</p></div><div><h3>Results</h3><p>Measures of puff topography did not differ significantly by e-liquid flavor (all <em>p</em> > .40). Similarly, menthol and tobacco flavored e-cigarettes were both rated positively in terms of subjective effects and behavioral intentions (all <em>p</em> > .10) and about 40 % of participants reported a preference for the tobacco-flavored e-liquid. Finally, participants showed comparable reductions in craving (<em>p</em> = .210) and withdrawal (<em>p</em> = .671) from pre- and post-session regardless of e-liquid flavor.</p></div><div><h3>Conclusions</h3><p>Among menthol smokers in a lab-based setting, findings suggest that menthol vs tobacco e-liquid flavor has little impact on acute changes in puff patterns, subjective experience, behavioral intentions, or craving and withdrawal.</p></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S030646032400087X/pdfft?md5=82a5a9243aa7a6669ac188278dbd81da&pid=1-s2.0-S030646032400087X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers\",\"authors\":\"Eleanor L.S. 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引用次数: 0
摘要
背景拟议的美国食品及药物管理局（FDA）产品标准禁止将薄荷脑作为可燃卷烟的特征香料，该标准有可能显著减少与烟草相关的健康差异。薄荷醇电子液体产品标准是会改善还是会阻碍公众健康尚不得而知。在随机交叉试验设计中，黑人（n = 47）和白人（n = 4）尼古丁缺乏且电子烟经验有限的薄荷卷烟吸食者完成了两次实验室内30分钟随意吸食薄荷和烟草尼古丁盐电子烟的平衡试验。问卷调查评估了渴望和戒断的减少情况，以及吸食后的主观体验和行为意向。在每次吸食过程中，都会连续测量吹出的气流地形。结果不同口味的电子液体对吹出的气流地形的测量结果没有显著差异（均为 p > .40）。同样，薄荷味和烟草味电子烟在主观效果和行为意向方面都获得了积极评价（所有 p > .10），约 40% 的参与者表示更喜欢烟草味电子烟液。结论在实验室环境中，研究结果表明，薄荷味与烟草味电子烟对吸食模式、主观体验、行为意向、渴望和戒断的急性变化影响甚微。
Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers
Background
The proposed FDA product standard to prohibit menthol as a characterizing flavor in combustible cigarettes has the potential to significantly reduce tobacco-related health disparities. Whether a menthol e-liquid product standard would improve or hinder public health is unknown. No known research has directly examined the impact of menthol vs. tobacco flavored e-liquid use on acute e-cigarette use patterns, subjective experience, behavioral intentions, and craving and withdrawal among menthol cigarette smokers.
Methods
Black (n = 47) and White (n = 4) nicotine-deprived menthol smokers with limited e-cigarette experience completed two counterbalanced in-laboratory 30-minute ad libitum vaping sessions with menthol and tobacco nicotine salt-based e-liquid in a randomized crossover pilot trial design. Questionnaires assessed reductions in craving and withdrawal and post-session subjective experience and behavioral intentions. Puff topography was measured continuously throughout each vaping session.
Results
Measures of puff topography did not differ significantly by e-liquid flavor (all p > .40). Similarly, menthol and tobacco flavored e-cigarettes were both rated positively in terms of subjective effects and behavioral intentions (all p > .10) and about 40 % of participants reported a preference for the tobacco-flavored e-liquid. Finally, participants showed comparable reductions in craving (p = .210) and withdrawal (p = .671) from pre- and post-session regardless of e-liquid flavor.
Conclusions
Among menthol smokers in a lab-based setting, findings suggest that menthol vs tobacco e-liquid flavor has little impact on acute changes in puff patterns, subjective experience, behavioral intentions, or craving and withdrawal.
期刊介绍：
Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings.
Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.
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