Marc Caragea , Austin Le , Tim Curtis , Amelia Ni , Tyler Clark , Andrew Joyce , Colton Hickman , Brandon Lawrence , Zane Randell , Perry Goodman , Addisyn Poduska , Michella Rasmussen , Amanda Cooper , Masaru Teramoto , Allison Glinka Przybysz , Taylor Burnham , Aaron Conger , Zachary L. McCormick
{"title":"腰椎内侧支射频神经切断术对成人脊柱侧凸患者科布角进展的影响与自然史的比较：横断面研究","authors":"Marc Caragea , Austin Le , Tim Curtis , Amelia Ni , Tyler Clark , Andrew Joyce , Colton Hickman , Brandon Lawrence , Zane Randell , Perry Goodman , Addisyn Poduska , Michella Rasmussen , Amanda Cooper , Masaru Teramoto , Allison Glinka Przybysz , Taylor Burnham , Aaron Conger , Zachary L. McCormick","doi":"10.1016/j.inpm.2024.100411","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Lumbar radiofrequency neurotomy (LRFN) effectively alleviates zygapophyseal joint-mediated pain by coagulating medial branch nerves to disrupt nociceptive signaling pathways. The concomitant denervation of multifidus fibers has led to concern that LRFN may increase segmental instability and accelerate degenerative changes in patients with certain pre-existing spinal pathologies. There is a paucity of literature evaluating whether LRFN increases the progression of spinal curvature in patients with adult scoliosis.</p></div><div><h3>Objective</h3><p>Compare the lumbosacral Cobb angle progression rate in patients with adult scoliosis who underwent LRFN to the annual progression rate of 0.83 ± 1.1° expected by natural history.</p></div><div><h3>Design</h3><p>Cross-sectional study.</p></div><div><h3>Methods</h3><p>Consecutive patients diagnosed with adult scoliosis who underwent LRFN to treat zygapophyseal joint-related low back pain were identified. Patient demographics, LRFN procedure details, and radiographs confirming scoliosis were collected from electronic medical records. Pre- and post-LRFN radiographs were used to calculate the average annual rate of Cobb angle progression. Data were analyzed using a Wilcoxon signed-rank test and a linear regression model.</p></div><div><h3>Results</h3><p>Sixty patients (mean age 69.2 ± 11.6 years; 70.0 % female) met the criteria and were included in the analyses. The mean time to radiographic follow-up was 35.0 ± 22.7 months post-LRFN. The average Cobb angle progression was 0.54 ± 3.03° per year and did not differ significantly from the known natural progression rate of 0.83 ± 1.1° per year. None of the included covariates (body mass index, LRFN laterality, and number of levels denervated) were significantly associated with the average annual Cobb angle progression rate.</p></div><div><h3>Conclusions</h3><p>Our results suggest that LRFN has no appreciable effect on the rate of Cobb angle progression in patients with adult scoliosis.</p></div>","PeriodicalId":100727,"journal":{"name":"Interventional Pain Medicine","volume":"3 2","pages":"Article 100411"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772594424000311/pdfft?md5=844938a50169ecb159c30a23575d8a49&pid=1-s2.0-S2772594424000311-main.pdf","citationCount":"0","resultStr":"{\"title\":\"The effect of lumbar medial branch radiofrequency neurotomy on cobb angle progression in individuals with adult scoliosis compared to natural history: A cross-sectional study\",\"authors\":\"Marc Caragea , Austin Le , Tim Curtis , Amelia Ni , Tyler Clark , Andrew Joyce , Colton Hickman , Brandon Lawrence , Zane Randell , Perry Goodman , Addisyn Poduska , Michella Rasmussen , Amanda Cooper , Masaru Teramoto , Allison Glinka Przybysz , Taylor Burnham , Aaron Conger , Zachary L. McCormick\",\"doi\":\"10.1016/j.inpm.2024.100411\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Lumbar radiofrequency neurotomy (LRFN) effectively alleviates zygapophyseal joint-mediated pain by coagulating medial branch nerves to disrupt nociceptive signaling pathways. The concomitant denervation of multifidus fibers has led to concern that LRFN may increase segmental instability and accelerate degenerative changes in patients with certain pre-existing spinal pathologies. There is a paucity of literature evaluating whether LRFN increases the progression of spinal curvature in patients with adult scoliosis.</p></div><div><h3>Objective</h3><p>Compare the lumbosacral Cobb angle progression rate in patients with adult scoliosis who underwent LRFN to the annual progression rate of 0.83 ± 1.1° expected by natural history.</p></div><div><h3>Design</h3><p>Cross-sectional study.</p></div><div><h3>Methods</h3><p>Consecutive patients diagnosed with adult scoliosis who underwent LRFN to treat zygapophyseal joint-related low back pain were identified. Patient demographics, LRFN procedure details, and radiographs confirming scoliosis were collected from electronic medical records. Pre- and post-LRFN radiographs were used to calculate the average annual rate of Cobb angle progression. Data were analyzed using a Wilcoxon signed-rank test and a linear regression model.</p></div><div><h3>Results</h3><p>Sixty patients (mean age 69.2 ± 11.6 years; 70.0 % female) met the criteria and were included in the analyses. The mean time to radiographic follow-up was 35.0 ± 22.7 months post-LRFN. The average Cobb angle progression was 0.54 ± 3.03° per year and did not differ significantly from the known natural progression rate of 0.83 ± 1.1° per year. None of the included covariates (body mass index, LRFN laterality, and number of levels denervated) were significantly associated with the average annual Cobb angle progression rate.</p></div><div><h3>Conclusions</h3><p>Our results suggest that LRFN has no appreciable effect on the rate of Cobb angle progression in patients with adult scoliosis.</p></div>\",\"PeriodicalId\":100727,\"journal\":{\"name\":\"Interventional Pain Medicine\",\"volume\":\"3 2\",\"pages\":\"Article 100411\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772594424000311/pdfft?md5=844938a50169ecb159c30a23575d8a49&pid=1-s2.0-S2772594424000311-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Interventional Pain Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772594424000311\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interventional Pain Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772594424000311","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of lumbar medial branch radiofrequency neurotomy on cobb angle progression in individuals with adult scoliosis compared to natural history: A cross-sectional study
Background
Lumbar radiofrequency neurotomy (LRFN) effectively alleviates zygapophyseal joint-mediated pain by coagulating medial branch nerves to disrupt nociceptive signaling pathways. The concomitant denervation of multifidus fibers has led to concern that LRFN may increase segmental instability and accelerate degenerative changes in patients with certain pre-existing spinal pathologies. There is a paucity of literature evaluating whether LRFN increases the progression of spinal curvature in patients with adult scoliosis.
Objective
Compare the lumbosacral Cobb angle progression rate in patients with adult scoliosis who underwent LRFN to the annual progression rate of 0.83 ± 1.1° expected by natural history.
Design
Cross-sectional study.
Methods
Consecutive patients diagnosed with adult scoliosis who underwent LRFN to treat zygapophyseal joint-related low back pain were identified. Patient demographics, LRFN procedure details, and radiographs confirming scoliosis were collected from electronic medical records. Pre- and post-LRFN radiographs were used to calculate the average annual rate of Cobb angle progression. Data were analyzed using a Wilcoxon signed-rank test and a linear regression model.
Results
Sixty patients (mean age 69.2 ± 11.6 years; 70.0 % female) met the criteria and were included in the analyses. The mean time to radiographic follow-up was 35.0 ± 22.7 months post-LRFN. The average Cobb angle progression was 0.54 ± 3.03° per year and did not differ significantly from the known natural progression rate of 0.83 ± 1.1° per year. None of the included covariates (body mass index, LRFN laterality, and number of levels denervated) were significantly associated with the average annual Cobb angle progression rate.
Conclusions
Our results suggest that LRFN has no appreciable effect on the rate of Cobb angle progression in patients with adult scoliosis.
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