革新神经系统疾病治疗:整合创新药物干预和先进治疗技术

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY Current pharmaceutical design Pub Date : 2024-04-15 DOI:10.2174/0113816128284824240328071911
Rimpi Arora, Ashish Baldi
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引用次数: 0

摘要

::神经系统疾病给个人带来沉重负担,导致残疾和生活质量下降。然而,近年来在治疗这些疾病的药物干预方面取得了显著进展。这篇综述文章旨在概述神经系统疾病治疗领域的最新创新和突破,重点关注阿尔茨海默病、帕金森病、多发性硬化症、癫痫和中风等关键治疗领域。本综述探讨了药物开发的新趋势,包括新型治疗靶点的确定、创新给药系统的开发以及个性化医疗方法的应用。此外,它还重点介绍了基因疗法、光遗传学和神经刺激技术等先进治疗技术的整合。这些技术有望精确调节神经回路,恢复神经元功能,甚至改变疾病。虽然这些进步为更有效、更有针对性的治疗带来了希望,但仍存在一些挑战,如需要改进诊断工具、确定新的干预目标以及优化给药方法。通过应对这些挑战并继续投资于研究与合作,我们可以彻底改变神经系统疾病的治疗方法,并显著改善这些疾病患者的生活。
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Revolutionizing Neurological Disorder Treatment: Integrating Innovations in Pharmaceutical Interventions and Advanced Therapeutic Technologies
:: Neurological disorders impose a significant burden on individuals, leading to disabilities and a reduced quality of life. However, recent years have witnessed remarkable advancements in pharmaceutical interventions aimed at treating these disorders. This review article aims to provide an overview of the latest innovations and breakthroughs in neurological disorder treatment, with a specific focus on key therapeutic areas such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, and stroke. This review explores emerging trends in drug development, including the identification of novel therapeutic targets, the development of innovative drug delivery systems, and the application of personalized medicine approaches. Furthermore, it highlights the integration of advanced therapeutic technologies such as gene therapy, optogenetics, and neurostimulation techniques. These technologies hold promise for precise modulation of neural circuits, restoration of neuronal function, and even disease modification. While these advancements offer hopeful prospects for more effective and tailored treatments, challenges such as the need for improved diagnostic tools, identification of new targets for intervention, and optimization of drug delivery methods remain. By addressing these challenges and continuing to invest in research and collaboration, we can revolutionize the treatment of neurological disorders and significantly enhance the lives of those affected by these conditions.
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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
302
审稿时长
2 months
期刊介绍: Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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