{"title":"1 型和 2 型糖尿病对骨髓炎风险的差异因果效应：孟德尔随机分析的启示","authors":"YanHui Li, Chuanyang Zhou, Liming Yang, Lei Tan","doi":"10.1101/2024.04.08.24305482","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Osteomyelitis (OM) poses a significant clinical challenge, especially among individuals with diabetes mellitus (DM). While both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) have been linked to an elevated risk of OM, the precise causal relationships remain uncertain.","PeriodicalId":501263,"journal":{"name":"medRxiv - Orthopedics","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Differential Causal Effects of Type 1 and Type 2 Diabetes on Osteomyelitis Risk: Insights from Mendelian Randomization Analysis\",\"authors\":\"YanHui Li, Chuanyang Zhou, Liming Yang, Lei Tan\",\"doi\":\"10.1101/2024.04.08.24305482\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> Osteomyelitis (OM) poses a significant clinical challenge, especially among individuals with diabetes mellitus (DM). While both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) have been linked to an elevated risk of OM, the precise causal relationships remain uncertain.\",\"PeriodicalId\":501263,\"journal\":{\"name\":\"medRxiv - Orthopedics\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Orthopedics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.04.08.24305482\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Orthopedics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.08.24305482","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景 骨髓炎（OM）是一项重大的临床挑战，尤其是在糖尿病（DM）患者中。虽然 1 型糖尿病（T1DM）和 2 型糖尿病（T2DM）都与 OM 风险升高有关，但确切的因果关系仍不确定。
Differential Causal Effects of Type 1 and Type 2 Diabetes on Osteomyelitis Risk: Insights from Mendelian Randomization Analysis
Background Osteomyelitis (OM) poses a significant clinical challenge, especially among individuals with diabetes mellitus (DM). While both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) have been linked to an elevated risk of OM, the precise causal relationships remain uncertain.
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