中国躁郁症患者丙戊酸钠血浆稳态浓度的回顾性分析：人口统计学和临床特征的影响。

IF 2.8 4区医学 Q2 MEDICAL LABORATORY TECHNOLOGY Therapeutic Drug Monitoring Pub Date : 2024-04-19 DOI:10.1097/ftd.0000000000001199

Qian Qiming, Zheng Ping, Li Huiqi, Xu Leyu, Li LIren, Lei Ming

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引用次数: 0

摘要

本研究全面考察了接受丙戊酸治疗的患者的人口统计学特征和临床特征，并探讨了这些特征对丙戊酸血浆浓度的潜在影响。所有入组患者均服用了缓释制剂。研究对包括剂量、年龄、性别、体重指数、联合用药和实验室检查结果等因素进行了深入调查，以评估它们对研究结果的潜在影响。

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Retrospective Analysis of Steady-State Sodium Valproate Plasma Concentrations in Chinese Patients With Bipolar Disorder: Impact of Demographic and Clinical Characteristics.

This study comprehensively examined the demographic and clinical characteristics of patients undergoing valproic acid therapy and explored their potential impact on plasma valproic acid concentrations. All enrolled patients were administered the extended-release formulation. An in-depth investigation of factors, including dose, age, sex, body mass index, co-administered medications, and laboratory test findings, was conducted to evaluate their potential influence on study outcomes.

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来源期刊

Therapeutic Drug Monitoring 医学-毒理学

CiteScore

5.00

自引率

8.00%

发文量

213

审稿时长

4-8 weeks

期刊介绍： Therapeutic Drug Monitoring is a peer-reviewed, multidisciplinary journal directed to an audience of pharmacologists, clinical chemists, laboratorians, pharmacists, drug researchers and toxicologists. It fosters the exchange of knowledge among the various disciplines–clinical pharmacology, pathology, toxicology, analytical chemistry–that share a common interest in Therapeutic Drug Monitoring. The journal presents studies detailing the various factors that affect the rate and extent drugs are absorbed, metabolized, and excreted. Regular features include review articles on specific classes of drugs, original articles, case reports, technical notes, and continuing education articles.