2022 年美国艾滋病毒感染者和非艾滋病毒感染者的高血压患病率和控制率。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-04-26 DOI:10.1093/ajh/hpae048
X. Weng, L. Kompaniyets, Kate Buchacz, Angela M. Thompson-Paul, R. Woodruff, Karen W. Hoover, Ya-Lin A Huang, Jun Li, Sandra L. Jackson
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引用次数: 0

摘要

背景HIV感染者(PWH)的心血管疾病发病率高于非HIV感染者。方法这项横断面研究纳入了 2022 年 IQVIATM Ambulatory Electronic Medical Record - US 数据中的成年患者。根据≥2 个 HIV 诊断代码或 HIV 检测呈阳性来确定是否感染 HIV。高血压根据诊断代码、≥2 次血压读数≥130/80 mmHg 或抗高血压药物处方确定。在高血压患者中,最近一次血压<130/80 mmHg即为控制。使用边际标准化方法建立的逻辑模型估算了所有患者和 PWH 患者中高血压和高血压控制率的调整患病率比(aPR),并控制了协变量。与未感染 HIV 的人群相比,PWH 的高血压患病率更高(66% vs 54%,aPR:1.14,95% CI:1.13-1.15)。在高血压患者中,与未感染艾滋病毒的人相比,威利人更有可能控制高血压(aPR:1.10,95% CI:1.07-1.13)。在艾滋病感染者中,来自南方的艾滋病感染者比来自东北部的艾滋病感染者更容易患高血压(aPR:1.07,95% CI:1.02-1.12),而黑人艾滋病感染者比白人艾滋病感染者更不容易控制高血压(aPR:0.72,95% CI:0.67-0.77)。在艾滋病感染者中,高血压患病率和控制率存在地域和种族差异。对艾滋病感染者的最佳治疗包括筛查、预防和控制高血压的综合策略。
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Hypertension Prevalence and Control Among People With and Without HIV - United States, 2022.
BACKGROUND People with HIV (PWH) have higher rates of cardiovascular disease than people without HIV. However, limited information exists about hypertension prevalence and associated risk factors in PWH. METHODS This cross-sectional study included adult patients in the 2022 IQVIATM Ambulatory Electronic Medical Record - US data. HIV was identified based on ≥2 HIV diagnosis codes or a positive HIV test. Hypertension was identified by diagnosis codes, ≥2 blood pressure (BP) readings ≥130/80 mmHg, or an antihypertensive medication prescription. Among those with hypertension, control was defined as most recent BP <130/80 mmHg. Logistic models using marginal standardization method were used to estimate adjusted prevalence ratios (aPR) of hypertension and hypertension control among all patients and PWH specifically, controlling for covariates. RESULTS Of 7,533,379 patients, 19,102 (0.3%) had HIV. PWH had higher hypertension prevalence (66% vs 54%, aPR:1.14, 95% CI: 1.13-1.15) compared with people without HIV. Among persons with hypertension, PWH were more likely to have controlled hypertension (aPR: 1.10, 95% CI: 1.07-1.13) compared with people without HIV. Among PWH, those from the South were more likely to have hypertension (aPR: 1.07, 95% CI: 1.02-1.12) than PWH from the Northeast, while Black PWH were less likely to have controlled hypertension (aPR: 0.72, 95% CI: 0.67-0.77) than White PWH. CONCLUSIONS PWH were more likely to have hypertension than people without HIV. Geographic and racial disparities in hypertension prevalence and control were observed among PWH. Optimal care for PWH includes comprehensive strategies to screen for, prevent, and manage hypertension.
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