基于电磁的柔性生物电子学及其应用

IF 1.9 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Frontiers in electronics Pub Date : 2024-04-25 DOI:10.3389/felec.2024.1240603
Shenyi Pan, Minghao Zhou, Longyin Liu, Huimin Shen
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摘要

随着人工设备与生物结构无缝对接的需求日益增长,柔性生物电子学近年来得到了快速发展。与传统的刚性生物电子器件相比,柔性器件更能适应生物体内外各部分的集成。生物医学设备、神经电子学和可穿戴设备等领域都取得了重大成就。随着柔性生物电子学的发展,电磁学正利用其在各种生物材料中穿透力强、反应迅速的优势,成为减少信号干扰、传输或反馈信息的关键部分。在这篇综述中,我们重点介绍了基于电磁学的柔性生物电子学的最新发展,涉及材料、传感、无缝集成和电源,以及在外部可穿戴设备、内部植入物、软机器人和药物输送系统等领域的最新成果。在此基础上,分析了柔性生物电子学面临的主要挑战,包括软硬元件机械性能不匹配导致的可拉伸性、生物兼容性、环境稳定性等,以促进柔性生物电子学的进一步发展。
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Electromagnetic based flexible bioelectronics and its applications
With the increasing demand in seamless interface between artificial devices and biological structures, flexible bioelectronics has been developed rapidly in recent years. Compared with traditional rigid bioelectronics, flexible devices are more adaptable to the integration for various parts both inside and outside of the organism. Significant achievements have been made in biomedical devices, neuroelectronics and wearable devices. With the development of flexible bioelectronics, electromagnetics is becoming a crucial part in signal interference reduction and information transmission or feedback, taking advantages of strong penetration and rapid response in a variety of biological materials. In this review, we focus on the latest developments in electromagnetic based flexible bioelectronics, involving materials, sensation, seamless integration, and power supply, as well as the latest achievements in the fields of external wearables, internal implants, soft robotics and drug delivery system. Based on these, the main challenges facing flexible bioelectronics, are analyzed, including stretchability caused by mismatch between mechanical properties of soft and hard components, biocompatibility, environmental stability, to facilitate the further development of flexible bioelectronics.
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