管理和控制病毒爆发的当代战略:概述

Mohammad Ejaz, Muhammad Ali Syed, Rani Faryal, Sheryar Jamil
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摘要

病毒因导致大量传染病而臭名昭著,是造成全球发病率和死亡率的主要因素。纵观历史,不同地区都曾爆发过病毒疫情、流行病和大流行病,造成了严重的死亡率。在 20 世纪最初的几十年里,流感病毒在全球范围内爆发并传播,造成了极高的死亡率,随后引发了大流行。这一灾难性事件导致超过 7 500 万人死亡,并伴随着大量疾病的发生。除了开发有效的病毒性疾病治疗方法外,当务之急是制定和实施各种预防措施,以减少疾病在本地和全球人口中的传播。此外,在加强监测系统的同时,还必须实施行之有效的常规和现代病毒感染管理策略。病毒的传播方式多种多样,包括呼吸道传播、口腔粪便传播、血液传播和病媒传播。因此,缓解病毒传播的有效措施必须针对每种不同的传播途径。本综述讨论了为减轻病毒传播和遏制病毒爆发以及疾病在大量人群中传播而采用的现有策略,旨在减少其对社区造成的有害和致命影响。
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Contemporary Strategies for Managing and Controlling Viral Outbreaks: An Overview
Viruses are notorious for causing a significant array of infectious diseases, rendering them a prominent contributor to global morbidity and mortality rates. Throughout history, various regions have experienced outbreaks, epidemics, and pandemics, resulting in significant mortality rates. The Influenza virus gave rise to highly fatal outbreaks that disseminated on a global scale, subsequently resulting in a pandemic during the initial decades of the 20th century. This catastrophic event led to >75 million fatalities, accompanied by a substantial incidence of illnesses. In addition to the development of efficacious treatments for viral diseases, it is imperative to establish and implement various preventive measures to mitigate the transmission of diseases within both local and global populations. Furthermore, it is critical to implement proven conventional and contemporary strategies for managing viral infections, alongside bolstered surveillance systems. Viruses employ diverse modes of transmission, encompassing respiratory, oral-fecal, blood-borne, and vector-borne pathways. Consequently, effective measures to mitigate viral dissemination must be tailored to address each distinct route of transmission. This review discusses the existing strategies employed to mitigate the transmission and containment of viral outbreaks, as well as the dissemination of the disease within a sizable population, intending to reduce their detrimental and fatal impacts on a community.
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