何首乌多糖的药理作用和机制研究进展

Maohui Yang, Ruhai Chen, Xin Zhou, Huaguo Chen
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引用次数: 0

摘要

何首乌是百合科何首乌属的药食同源植物,含有多糖、蛋白质、生物碱、木质素、氨基酸等多种成分。大量研究表明,何首乌多糖是何首乌的主要活性成分,具有抗氧化、免疫调节、抗肿瘤、降血糖等药理作用。本文总结了近 10 年来对何首乌多糖生物活性及作用机理的研究,探讨了何首乌多糖的结构-活性关系对其作用机理的影响。展望了何首乌多糖的研究和应用前景,以期为相关药物和健康食品的开发提供参考。
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Research Progress on Pharmacological Effects and Mechanism of Polygonatum sibiricum Polysaccharides
Polygonatum sibiricum is a medicinal and edible homologous plant of Polygonatum in Liliaceae, which contains many components, such as polysaccharides, proteins, alkaloids, lignans, and amino acids. A large number of studies have shown that Polygonatum sibiricum polysaccharide is the main active component of Polygonatum sibiricum, which has pharmacological effects, such as antioxidant, immune regulation, antitumor, hypoglycemic, and so on. In this article, the research on bioactivity and mechanism of Polygonatum sibiricum polysaccharide in recent 10 years is summarized, and the effect of structure–activity relationship of Polygonatum sibiricum polysaccharide on the mechanism of action is discussed. The research and application prospect of Polygonatum sibiricum polysaccharide in order is prospected to provide reference for the development of related drugs and healthy food.
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