{"title":"革新口腔癌治疗:免疫治疗方法","authors":"Md Moidul Islam, Sarjana Raikwar","doi":"10.2174/0115733947290954240402060311","DOIUrl":null,"url":null,"abstract":"\n\nImmunotherapy is a promising addition to the cancer treatment arsenal, with\nthe potential to be an effective adjuvant therapy. In the ever-changing landscape of cancer care, it\nappears as a potential fourth pillar, supplementing surgery, chemotherapy, and radiation. The key to\neffective immunotherapy is cautious patient selection, which is based on a thorough study of the\nunique immune makeup of each patient.\n\n\n\nThis review article aims to provide a comprehensive understanding of the fundamental principles\nof tumor immunity and immunotherapy, with a specific focus on oral squamous cell carcinoma.\n\n\n\nThe review involved a thorough investigation of scientific databases and relevant publications,\nincluding studies conducted up to the present date obtained from PubMed, Science Direct, and\nGoogle Scholar Key. The selected studies underwent careful evaluation for methodological rigor and\nthe significance of their findings.\n\n\n\nCheckpoint inhibitors, targeted monoclonal antibodies, adoptive cell transfer, cancer vaccines,\nbiomarkers and prediction tools, and cytokine immunotherapy are all promising treatments for\noral cancer.\n\n\n\nIn recent decades, there has been a substantial increase in interest and study in cancer\nimmunotherapy, indicating a turning point in our approach to cancer treatment. While significant\nprogress has been made, major hurdles remain across a range of cancers.\n","PeriodicalId":503819,"journal":{"name":"Current Cancer Therapy Reviews","volume":" 33","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Revolutionizing Oral Cancer Treatment: Immunotherapeutic Approaches\",\"authors\":\"Md Moidul Islam, Sarjana Raikwar\",\"doi\":\"10.2174/0115733947290954240402060311\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nImmunotherapy is a promising addition to the cancer treatment arsenal, with\\nthe potential to be an effective adjuvant therapy. In the ever-changing landscape of cancer care, it\\nappears as a potential fourth pillar, supplementing surgery, chemotherapy, and radiation. The key to\\neffective immunotherapy is cautious patient selection, which is based on a thorough study of the\\nunique immune makeup of each patient.\\n\\n\\n\\nThis review article aims to provide a comprehensive understanding of the fundamental principles\\nof tumor immunity and immunotherapy, with a specific focus on oral squamous cell carcinoma.\\n\\n\\n\\nThe review involved a thorough investigation of scientific databases and relevant publications,\\nincluding studies conducted up to the present date obtained from PubMed, Science Direct, and\\nGoogle Scholar Key. The selected studies underwent careful evaluation for methodological rigor and\\nthe significance of their findings.\\n\\n\\n\\nCheckpoint inhibitors, targeted monoclonal antibodies, adoptive cell transfer, cancer vaccines,\\nbiomarkers and prediction tools, and cytokine immunotherapy are all promising treatments for\\noral cancer.\\n\\n\\n\\nIn recent decades, there has been a substantial increase in interest and study in cancer\\nimmunotherapy, indicating a turning point in our approach to cancer treatment. While significant\\nprogress has been made, major hurdles remain across a range of cancers.\\n\",\"PeriodicalId\":503819,\"journal\":{\"name\":\"Current Cancer Therapy Reviews\",\"volume\":\" 33\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Cancer Therapy Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/0115733947290954240402060311\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cancer Therapy Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115733947290954240402060311","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
免疫疗法是癌症治疗武器库中一个前景广阔的新成员,有可能成为一种有效的辅助疗法。在瞬息万变的癌症治疗领域,免疫疗法有望成为补充手术、化疗和放疗的第四大支柱。这篇综述文章旨在提供对肿瘤免疫和免疫疗法基本原理的全面理解,特别关注口腔鳞状细胞癌。综述涉及对科学数据库和相关出版物的全面调查,包括从 PubMed、Science Direct 和 Google Scholar Key 获取的截至目前进行的研究。检查点抑制剂、靶向单克隆抗体、收养性细胞转移、癌症疫苗、生物标记物和预测工具以及细胞因子免疫疗法都是治疗口腔癌的有前途的方法。近几十年来,人们对癌症免疫疗法的兴趣和研究大幅增加,这表明我们的癌症治疗方法到了一个转折点。虽然已经取得了重大进展,但在一系列癌症中仍存在重大障碍。
Revolutionizing Oral Cancer Treatment: Immunotherapeutic Approaches
Immunotherapy is a promising addition to the cancer treatment arsenal, with
the potential to be an effective adjuvant therapy. In the ever-changing landscape of cancer care, it
appears as a potential fourth pillar, supplementing surgery, chemotherapy, and radiation. The key to
effective immunotherapy is cautious patient selection, which is based on a thorough study of the
unique immune makeup of each patient.
This review article aims to provide a comprehensive understanding of the fundamental principles
of tumor immunity and immunotherapy, with a specific focus on oral squamous cell carcinoma.
The review involved a thorough investigation of scientific databases and relevant publications,
including studies conducted up to the present date obtained from PubMed, Science Direct, and
Google Scholar Key. The selected studies underwent careful evaluation for methodological rigor and
the significance of their findings.
Checkpoint inhibitors, targeted monoclonal antibodies, adoptive cell transfer, cancer vaccines,
biomarkers and prediction tools, and cytokine immunotherapy are all promising treatments for
oral cancer.
In recent decades, there has been a substantial increase in interest and study in cancer
immunotherapy, indicating a turning point in our approach to cancer treatment. While significant
progress has been made, major hurdles remain across a range of cancers.