{"title":"卵巢大面积水肿和纤维瘤病:罕见病例报告","authors":"Thanka Johnson, Abhishri Lakshmi K","doi":"10.18231/j.ijpo.2024.021","DOIUrl":null,"url":null,"abstract":"Ovarian lesions composed of spindle cells comprise a heterogeneous group; most are neoplastic, but several non-neoplastic lesions may be composed of spindle cells, including massive edema and fibromatosis and ovarian fibroma. Herein we discuss both these non- neoplastic entities as a differential diagnosis for our case of benign spindle cell lesion of ovary.57-year-old post-menopausal female presented with abdominal pain, vomiting, constipation. Computed tomography showed, features of ovarian torsion. Staging laparotomy was done and a specimen of hysterectomy with bilateral salpingoophorectomy, was sent for histopathological examination. Sections from right ovary showed proliferation of spindle cells resembling stromal fibroblasts with large areas of edema and haemorrhage. Masson's trichrome show increased collagen deposition. The tube also shows changes secondary to torsion in the wall. Based on the above features, we made a diagnosis of benign spindle cell lesion of ovary with the differential diagnosis including massive edema and fibromatosis and fibroma of ovary. IHC for Inhibin was ordered which came negative. This confirmed the diagnosis of massive edema and fibromatosis.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"16 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Massive edema and fibromatosis of ovary: A rare case report\",\"authors\":\"Thanka Johnson, Abhishri Lakshmi K\",\"doi\":\"10.18231/j.ijpo.2024.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ovarian lesions composed of spindle cells comprise a heterogeneous group; most are neoplastic, but several non-neoplastic lesions may be composed of spindle cells, including massive edema and fibromatosis and ovarian fibroma. Herein we discuss both these non- neoplastic entities as a differential diagnosis for our case of benign spindle cell lesion of ovary.57-year-old post-menopausal female presented with abdominal pain, vomiting, constipation. Computed tomography showed, features of ovarian torsion. Staging laparotomy was done and a specimen of hysterectomy with bilateral salpingoophorectomy, was sent for histopathological examination. Sections from right ovary showed proliferation of spindle cells resembling stromal fibroblasts with large areas of edema and haemorrhage. Masson's trichrome show increased collagen deposition. The tube also shows changes secondary to torsion in the wall. Based on the above features, we made a diagnosis of benign spindle cell lesion of ovary with the differential diagnosis including massive edema and fibromatosis and fibroma of ovary. IHC for Inhibin was ordered which came negative. This confirmed the diagnosis of massive edema and fibromatosis.\",\"PeriodicalId\":486471,\"journal\":{\"name\":\"Indian Journal of Pathology and Oncology\",\"volume\":\"16 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Pathology and Oncology\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijpo.2024.021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Pathology and Oncology","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.18231/j.ijpo.2024.021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Massive edema and fibromatosis of ovary: A rare case report
Ovarian lesions composed of spindle cells comprise a heterogeneous group; most are neoplastic, but several non-neoplastic lesions may be composed of spindle cells, including massive edema and fibromatosis and ovarian fibroma. Herein we discuss both these non- neoplastic entities as a differential diagnosis for our case of benign spindle cell lesion of ovary.57-year-old post-menopausal female presented with abdominal pain, vomiting, constipation. Computed tomography showed, features of ovarian torsion. Staging laparotomy was done and a specimen of hysterectomy with bilateral salpingoophorectomy, was sent for histopathological examination. Sections from right ovary showed proliferation of spindle cells resembling stromal fibroblasts with large areas of edema and haemorrhage. Masson's trichrome show increased collagen deposition. The tube also shows changes secondary to torsion in the wall. Based on the above features, we made a diagnosis of benign spindle cell lesion of ovary with the differential diagnosis including massive edema and fibromatosis and fibroma of ovary. IHC for Inhibin was ordered which came negative. This confirmed the diagnosis of massive edema and fibromatosis.