应用耳穴按摩治疗失眠的有效性:系统回顾和荟萃分析

Li Jun, Li Xiong, Yu Wen, Yongxiang Wang
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摘要

失眠影响着全球许多人的生活质量。尽管药物睡眠治疗能短暂提高睡眠质量,但仍不建议用于长期治疗睡眠问题。针对这一问题,我们的研究旨在通过系统综述和荟萃分析来评估耳穴按摩治疗失眠症的有效性。耳穴按摩治疗失眠症的随机对照试验(RCT)数据来自五个英文数据库(Cochrane Central Register of Controlled Trials、MEDLINE、EMBASE、AMED 和 CINAHL)和四个中文数据库(CBM、CNKI、CQVIP 和 Wanfang)。相关数据由两名审稿人提取。采用 I2 统计法评估异质性。采用网络荟萃分析比较耳穴贴敷与其他方法的效果。共纳入 23 项研究,涉及 1,689 名患者。结果显示,与对照组相比,干预组的匹兹堡睡眠质量指数(PSQI)得分明显下降[SMD = -1.30, 95% CI (-1.65, -0.96),I2 = 90%]。此外,与常规护理组相比,在常规护理基础上接受耳穴穴位按摩的干预组的 PSQI 分数更低[SMD = -1.13, 95% CI (-1.33, -0.93),I2 = 23%]。研究发现,耳穴穴位按摩可增强艾司唑仑改善 PSQI 评分的效果,耳穴穴位按摩和艾司唑仑联合使用可降低 PSQI 评分[MD = -4.8,95% CI (-7.4, -2.1)]。重要的是,没有严重不良事件的报告。在中风后失眠患者中,干预组(接受耳穴穴位按摩)的 PSQI 得分低于对照组 [SMD = -0.74,95% CI (-1.03, -0.46),I2 = 0%]。同样,在癌症相关失眠患者中,与对照组相比,干预组(接受耳穴穴位按摩)的 PSQI 得分较低 [SMD = -0.99,95% CI (-1.37,-0.61),I2 = 0%]。此外,耳穴按摩可作为艾司唑仑或其他干预措施的辅助治疗,有效改善失眠症状。
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Effectiveness of applying auricular acupressure to treat insomnia: a systematic review and meta-analysis
Insomnia affects the quality of life of a significant number of individuals worldwide. Despite the fact that pharmaceutical sleep treatments have shown brief enhancements in sleep quality, these are still not recommended for the long-term management of sleep issues. To deal with this problem, our study aims to assess the effectiveness of auricular acupressure for treating insomnia by conducting a systematic review and meta-analysis.Data from randomized controlled trials (RCTs) of auricular acupressure for insomnia was collected from five English-language databases (Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, AMED, and CINAHL) and four Chinese databases (CBM, CNKI, CQVIP, and Wanfang). Relevant data were extracted by two reviewers. I2 statistics were adopted to appraise heterogeneity. A network meta-analysis was applied to compare the effect of auricular acupressure with other methods.In all, 23 RCTs involving a total of 1,689 patients were included. The results demonstrated a significant decrease in the Pittsburgh Sleep Quality Index (PSQI) score for the intervention group compared to the control group [SMD = −1.30, 95% CI (−1.65, −0.96), I2 = 90%]. Furthermore, the group receiving auricular acupressure in addition to usual care showed a lower PSQI score compared to the usual care group [SMD = −1.13, 95% CI (−1.33, −0.93), I2 = 23%]. Auricular acupressure was found to enhance the effectiveness of estazolam in improving PSQI score, with the combination of auricular acupressure and estazolam resulting in a lower PSQI score [MD = −4.8, 95% CI (−7.4, −2.1)]. Importantly, no serious adverse events were reported. In patients with insomnia following stroke, the intervention group (which received auricular acupressure) exhibited a lower PSQI score compared to the control group [SMD = −0.74, 95% CI (−1.03, −0.46), I2 = 0%]. Similarly, in patients with insomnia related to cancer, the intervention group (receiving auricular acupressure) demonstrated a lower PSQI score compared to the control group [SMD = −0.99, 95% CI (−1.37, −0.61), I2 = 0%].The effects of auricular acupressure on insomnia are comparable to those of estazolam. Furthermore, auricular acupressure can serve as a complementary treatment to estazolam or other interventions, effectively improving symptoms of insomnia.
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