利用块茎薤叶的水提取物绿色合成金纳米粒子

IF 0.5 Q4 ENGINEERING, BIOMEDICAL Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2024-04-10 DOI:10.4028/p-4dixjm
P. Eugenio, Arra Jane De Guzman, Eduardo L. Sanidad, Sunshine C. Asuncion, Roseanne G. Dela Cruz, Paulo B. Patricio, Benedick A. Peralta, Harvey D. Torres, J. Monserate
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引用次数: 0

摘要

金纳米粒子(AuNPs)具有应用广泛、生物相容性好、毒性低和可定制的稳定性等优点,因此在生物材料和生物医学工程领域备受关注。本研究的重点是通过一种环境友好型方法合成 AuNPs,特别是利用块茎薤白的水性叶提取物作为还原剂和封端剂。利用紫外可见光谱对合成的 AuNPs 进行了表征,发现 AuNPs 的表面等离子共振 (SPR) 在 548 纳米处有一个吸收峰。通过扫描电子显微镜(SEM)进行的形态分析表明,AuNPs 既有棒状,也有球状,其尺寸为 41.0 nm(宽)和 181.6 nm(长)。EDX 分析证实,合成的 AuNPs 中金的含量很高。此外,-26.2 mV 的 zeta 电位值表明 AuNPs 具有良好的稳定性。植物化学分析和傅立叶变换红外光谱结果表明,块茎薤叶提取物中的皂苷在减少金属离子和稳定 AuNPs 方面发挥了重要作用。块茎薤叶提取物在合成各种金属纳米粒子方面的潜力凸显了其在生物材料和生物医学工程方面的前景。合成的 AuNPs 在靶向药物递送、无创成像和新兴生物医学用途等方面显示出多功能性。
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Green Synthesis of Gold Nanoparticles using Aqueous Extract of Allium tuberosum Leaves
Gold nanoparticles (AuNPs) have garnered significant interest in the field of biomaterials and biomedical engineering due to their wide-ranging applications, excellent biocompatibility, low toxicity, and customizable stability. This study focuses on synthesizing AuNPs through an environmentally friendly approach, specifically by utilizing the aqueous leaf extract of Allium tuberosum as both a reducing and capping agent. The synthesized AuNPs were characterized using UV-Vis Spectroscopy, revealing an absorption peak at 548 nm within the surface plasmon resonance (SPR) of AuNPs. Morphological analysis conducted via SEM showed a mixture of rod-shaped and spherical-shaped AuNPs, with dimensions of 41.0 nm (width) and 181.6 nm (length) confirmed through DLS measurements. EDX analysis confirmed the high abundance of gold in the synthesized AuNPs. Furthermore, a zeta potential value of -26.2 mV indicates that the AuNPs have decent stability. Phytochemical analyses and FT-IR results implicated that the Saponin present in the Allium tuberosum leaf extract played a crucial role in reducing metal ions and stabilizing the AuNPs. The potential of Allium tuberosum leaf extract for synthesizing diverse metal nanoparticles highlights its promise for biomaterials and biomedical engineering. The synthesized AuNPs show versatility for applications like targeted drug delivery, non-invasive imaging, and emerging biomedical uses.
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CiteScore
1.40
自引率
14.30%
发文量
73
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