血液 Hba1c 与空腹和餐后血糖的相关性研究

Pankaj Kumar, A. Nagdeote, Parul Gupta, A. Jadhao
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摘要

研究目的本研究旨在评估血糖升高与糖化血红蛋白(HbA1c)之间的相关性,糖化血红蛋白是评估血糖控制情况的金标准检测指标。连续监测糖尿病患者的 HbA1C 有助于预防微血管和大血管并发症:我们对因各种原因到医院就诊的 397 名患者的化验报告进行了回顾性分析。研究组中有 195 名男性和 202 名女性。我们评估了 HbA1c 与血糖控制的两个指标:空腹血糖(FBG)和餐后血糖(PPBG)之间的相关性:结果:空腹血糖(FBG)和餐后血糖(PPBG)均与 HbA1c 呈显著正相关。但 PPBG 与 HbA1c 的相关性比 FBG 更强。FBG与HbA1c的斯皮尔曼相关系数(r)为0.610(P<0.05),PPBG与HbA1c的斯皮尔曼相关系数(r)为0.683(P<0.05):结论:PPBG 比 FBG 更能预测 HbA1c。结论:PPBG 比 FBG 更能预测 HbA1c,PPBG 可作为 HbA1c 的替代指标,用于糖尿病的管理和监测。
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A CORRELATION STUDY OF BLOOD HBA1C WITH FASTING AND POSTPRANDIAL BLOOD GLUCOSE
Objectives: This study aimed to evaluate the correlation between raised blood sugar and glycated hemoglobin (HbA1c), a gold standard test for the assessment of glycemic control. Serial monitoring of HbA1C in diabetes mellitus helps in the prevention of microvascular and macrovascular complications. Methods: We retrospectively reviewed the laboratory reports of 397 patients who visited the hospital for various reasons. There were 195 males and 202 females in the study group. We evaluated the correlation between HbA1c and two indicators of glycemic control: fasting blood glucose (FBG) and postprandial blood glucose (PPBG). Results: Both FBG and PPBG showed a significant positive correlation with HbA1c. However, PPBG had a stronger correlation with HbA1c than FBG. The Spearman’s correlation coefficient (r) was 0.610 (p<0.05) for FBG and HbA1c and 0.683 (p<0.05) for PPBG and HbA1c. Conclusions: PPBG was a better predictor of HbA1c than FBG. PPBG may be an alternative marker of HbA1c for the management and monitoring of diabetes mellitus.
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