肠梗阻是转移性胃肠道神经内分泌肿瘤的一种表现形式--病例报告和文献综述

Y. Brahmi, Mahmoud Dabbagh, Ballouch Mohamed, Noufou Fodiya Moctar, Walid Chair, Mohammed Najih
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摘要

神经内分泌肿瘤(NET)是一种能够向血液中分泌激素的罕见肿瘤。它们可以影响任何器官,但最常见于消化系统,尤其是小肠。神经内分泌肿瘤(NET)通常在晚期由于出现非特异性症状而被发现。 嗜铬粒蛋白 A 是检测 NET 的主要生化指标。评估疾病的程度通常需要采用常规成像技术,如 CT 扫描和核磁共振成像,以及同位素成像方法。治愈性手术仍是治疗小肠神经内分泌肿瘤(SI-NET)的金标准。即使是处于转移期的病例,也应尽早考虑手术治疗。体生长抑素类似物(SSA)在控制症状和治疗转移性神经内分泌肿瘤(NETs)方面都起着关键作用。我们介绍了一例伴有肠梗阻的神经内分泌肿瘤病例,并进行了文献综述。
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Intestinal Obstruction as a Manifestation of Metastatic Gastrointestinal Neuroendocrine Tumor – A Case Report and Literature Review
Neuroendocrine tumors (NETs) are rare tumors that are capable of secreting hormones into the bloodstream. They can affect any organ but are most commonly found in the digestive system, particularly in the small intestine. Neuroendocrine tumors (NETs) are often identified in later stages due to the emergence of nonspecific symptoms.  Chromogranin A serves as the primary biochemical indicator for NETs. Evaluating the extent of the disease typically involves conventional imaging techniques such as CT scans and MRIs, as well as isotopic imaging methods. Curative surgery remains the gold standard in the management of small intestine neuroendocrine tumors (SI-NETs). It should be considered as soon as possible, even in cases of metastatic stage. Somatostatin analogs (SSAs) are pivotal in both managing symptoms and therapeutically addressing metastatic Neuroendocrine Tumors (NETs). we present a case of a neuroendocrine tumor with intestinal obstruction along with a literature review.
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