腰围身高比是否比其他肥胖指数更能确定心血管风险?

A. Salawu, S. Ojedokun, Joel Akande, T. Oloyede
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摘要

背景:据观察,肥胖指数(以体重指数、腰围和体重身高比衡量)与心血管风险密切相关。体重指数(BMI)是衡量全身性肥胖的指标,而腰围(WC)和腰围身高比(WHTR)则用于衡量中心性肥胖,后者被认为是预测心血管风险的指标。本研究旨在确定 WHtR 与其他肥胖指数相比在心血管风险方面的优势:本研究采用横断面描述性设计,研究对象为奥博莫索代谢研究实验室(LTH Ogomoso)的441名参与者,不包括孕妇或哺乳期妇女、甲状腺疾病患者、确诊为高血压、糖尿病或高脂血症患者、服用降血压、降血糖或降血脂药物者、服用体重控制药物或补充剂者。为了获得参与者的社会人口学数据,我们发放了一份结构化的自填问卷。对参与者进行了体格检查和人体测量。采集空腹血样,以测定血糖和血脂。数据分析采用 SPSS 21 版本:研究包括 441 名受试者,男女比例为 1:1.47,平均年龄分别为(37.92±11.80)岁和(34.72±12.16)岁。男性的血压、脉搏、身高和除腰围以外的其他肥胖指数均明显高于女性,差异有统计学意义(P<0.05)。在所有类别中,性别间的体重指数差异都有统计学意义,大多数女性受试者的体重指数和腰围都不正常。所有肥胖指数(BMI、WHtR 和 WC)与心血管风险因素(TG 和 HDLC 除外)之间均有统计学意义(P <0.05):据观察,本研究中测量的所有肥胖指数在确定心血管风险方面都很敏感且有意义。可以得出的结论是,WHtR 与 BMI 和 WC 相比并没有特殊或更大的优势,因为所有指数都与心血管风险有显著关联。此外,统计显著性水平表明,这些肥胖指数中的任何一个都可以单独用作心血管风险的预测指标。
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Is Waist to Height Ratio Better than Other Indices of Obesity in Determining Cardiovascular Risk?
Background: The indices of obesity (measured by Body Mass Index, waist circumference, and weight-to-height ratio) have been observed to be strongly associated with cardiovascular risk. Body mass index (BMI) is a measure of general obesity while waist circumference (WC) and waist-to-height ratio (WHtR) are used to measure central obesity, with the latter suggested to be the indicator for the prediction of cardiovascular risks. This study aimed to determine the advantage of WHtR for cardiovascular risk over the use of other indices of obesity. Methods: The study was a cross-sectional descriptive design carried out among 441 participants at the Metabolic Research Laboratory LTH Ogbomoso excluding pregnant or breastfeeding mothers, thyroid disease, those diagnosed with hypertension, diabetes, or hyperlipidemia, those on blood-pressure, blood-glucose or lipid-lowering medications; those on weight-control medications or supplements. A structured self-administer questionnaire was distributed to obtain socio-demographic data of participants. Physical examination was done with anthropometry measurements. Fasting blood samples were obtained for blood glucose and lipid profiles. Data analysis was done using SPSS version 21. Results: The study included 441 subjects with male to female ratio of 1:1.47 mean age of 37.92±11.80 and 34.72±12.16 respectively. Blood pressure, pulse rate, height and other obesity indices except waist circumference were all statistically significantly higher in the males than in the females p <0.05. There was a statistically significant difference in the BMI between the sexes for all categories with the majority of female subjects having abnormal BMI and waist circumference. There was a statistically significant relationship between all the obesity indices (BMI, WHtR & WC) and the cardiovascular risk factors excluding TG and HDLC P <0.05. Conclusion: It was observed that all indices of obesity measured in this study were sensitive and significant in determining cardiovascular risk. It could be concluded that WHtR does not have a special or greater advantage over BMI and WC as all indices showed a significant association with cardiovascular risks. Also, the level of statistical significance suggested  that either of these obesity indices could be used independently as a predictor of cardiovascular risk.
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