Zayra Carolina, Rojas Castillo, Elizabeth Ruíz López, Moisés Moreno Noguez, Eleane Daniela Solorio Adame, Blanca Estela, Herrera Morales, Luis Rey, García Cortés, Olga Lidia, Toxqui Delgado, Victor Itai, Urbalejo Ceniceros, Dana Aline Pérez Camargo, Victor Manuel Enriquez Estrada, María Rebeca Velasco Domínguez
{"title":"血脂异常与慢性肾功能衰竭 KDIGO ≥ 3 患者肾小球滤过率降低的关系","authors":"Zayra Carolina, Rojas Castillo, Elizabeth Ruíz López, Moisés Moreno Noguez, Eleane Daniela Solorio Adame, Blanca Estela, Herrera Morales, Luis Rey, García Cortés, Olga Lidia, Toxqui Delgado, Victor Itai, Urbalejo Ceniceros, Dana Aline Pérez Camargo, Victor Manuel Enriquez Estrada, María Rebeca Velasco Domínguez","doi":"10.29011/2574-7754.101740","DOIUrl":null,"url":null,"abstract":"Objective. To determine the association of dyslipidemia with decreased glomerular filtration rate (eGFR) in patients with CKD KDIGO ≥3. Material and methods. Observational, analytical, longitudinal, ambispective study; was carried out at the Family Medicine Unit (UMF) No. 55 Zumpango, the sample size was calculated using the mean difference formula, with an expected mean of 5.2, obtaining n= 90 patients with CKD KDIGO ≥3 , between 20-69 years. Patients with dyslipidemia and without dyslipidemia were classified into 2 groups, in which creatinine was evaluated to calculate the estimated glomerular filtration rate (eGFR), total cholesterol and triglycerides, subjects with renal function replacement therapy, patients with pathologies or treatments that modify lipid metabolism. For the bivariate analysis, the Student’s T test and the Mann-Whitney U test were applied according to the type of distribution presented by the eGFR values for the groups with and without dyslipidemia. Result and conclusion. Based on the eGFR values for the groups with and without dyslipidemia, they show that patients aged 20 to 69 years with CKD KDIGO ≥ 3 with dyslipidemia presented a mean eGFR of 40.24 for the first analysis, and 34.70 for the follow-up analysis., with a mean difference of 5.53, which was significant (p=0.003).","PeriodicalId":72213,"journal":{"name":"Annals of case reports","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association of Dyslipidemia in Decreased Glomerular Filtration Rate in Patients with CKD KDIGO ≥ 3\",\"authors\":\"Zayra Carolina, Rojas Castillo, Elizabeth Ruíz López, Moisés Moreno Noguez, Eleane Daniela Solorio Adame, Blanca Estela, Herrera Morales, Luis Rey, García Cortés, Olga Lidia, Toxqui Delgado, Victor Itai, Urbalejo Ceniceros, Dana Aline Pérez Camargo, Victor Manuel Enriquez Estrada, María Rebeca Velasco Domínguez\",\"doi\":\"10.29011/2574-7754.101740\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective. To determine the association of dyslipidemia with decreased glomerular filtration rate (eGFR) in patients with CKD KDIGO ≥3. Material and methods. Observational, analytical, longitudinal, ambispective study; was carried out at the Family Medicine Unit (UMF) No. 55 Zumpango, the sample size was calculated using the mean difference formula, with an expected mean of 5.2, obtaining n= 90 patients with CKD KDIGO ≥3 , between 20-69 years. Patients with dyslipidemia and without dyslipidemia were classified into 2 groups, in which creatinine was evaluated to calculate the estimated glomerular filtration rate (eGFR), total cholesterol and triglycerides, subjects with renal function replacement therapy, patients with pathologies or treatments that modify lipid metabolism. For the bivariate analysis, the Student’s T test and the Mann-Whitney U test were applied according to the type of distribution presented by the eGFR values for the groups with and without dyslipidemia. Result and conclusion. Based on the eGFR values for the groups with and without dyslipidemia, they show that patients aged 20 to 69 years with CKD KDIGO ≥ 3 with dyslipidemia presented a mean eGFR of 40.24 for the first analysis, and 34.70 for the follow-up analysis., with a mean difference of 5.53, which was significant (p=0.003).\",\"PeriodicalId\":72213,\"journal\":{\"name\":\"Annals of case reports\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of case reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29011/2574-7754.101740\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of case reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29011/2574-7754.101740","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Association of Dyslipidemia in Decreased Glomerular Filtration Rate in Patients with CKD KDIGO ≥ 3
Objective. To determine the association of dyslipidemia with decreased glomerular filtration rate (eGFR) in patients with CKD KDIGO ≥3. Material and methods. Observational, analytical, longitudinal, ambispective study; was carried out at the Family Medicine Unit (UMF) No. 55 Zumpango, the sample size was calculated using the mean difference formula, with an expected mean of 5.2, obtaining n= 90 patients with CKD KDIGO ≥3 , between 20-69 years. Patients with dyslipidemia and without dyslipidemia were classified into 2 groups, in which creatinine was evaluated to calculate the estimated glomerular filtration rate (eGFR), total cholesterol and triglycerides, subjects with renal function replacement therapy, patients with pathologies or treatments that modify lipid metabolism. For the bivariate analysis, the Student’s T test and the Mann-Whitney U test were applied according to the type of distribution presented by the eGFR values for the groups with and without dyslipidemia. Result and conclusion. Based on the eGFR values for the groups with and without dyslipidemia, they show that patients aged 20 to 69 years with CKD KDIGO ≥ 3 with dyslipidemia presented a mean eGFR of 40.24 for the first analysis, and 34.70 for the follow-up analysis., with a mean difference of 5.53, which was significant (p=0.003).