类风湿性关节炎患者因脊髓Ⅰ型畸形接受颅颈交界处减压术后出现小脑脓肿:病例报告

Andreas Papacharalampous, Theoklis Kouyialis, Petros Stylianou
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引用次数: 0

摘要

奇拉氏畸形 "是一组涉及颅颈交界处的病变。最常见的是Chiari I畸形(CIM),其特征是小脑扁桃体通过枕骨大孔向下脱位。有症状的患者和患有鞘膜积液的患者都适合进行颅颈交界处减压术。文献中描述了这种手术后的各种并发症。据我们所知,这是文献中首次描述类风湿性关节炎(RA)患者在接受颅颈交界处减压术治疗 CIM 后出现小脑脓肿的病例。我们认为,类风湿性关节炎及其治疗是导致这一并发症的主要原因,这主要是由于类风湿性关节炎导致的免疫功能损害和微妙的感染性临床表现。该病例促使我们改变了我科对接受脊柱手术的 RA 患者的围手术期管理。我们建议脊柱外科医生在治疗RA患者时应采取严格的感染预防措施,并对感染保持高度怀疑。
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Cerebellar Abscess Following Craniocervical Junction Decompression for Chiari I Malformation in a Patient with Rheumatoid Arthritis: A Case Report
‘Chiari Malformations’ are a group of pathologies involving the Craniocervical junction. The most common is Chiari I malformation (CIM), which is characterised by a downward dislocation of the cerebellar tonsils through the foramen magnum. Symptomatic patients and those with syringomyelia are candidates for decompression of the Craniocervical junction. A variety of complications have been described in the literature following this procedure. We present the case of a cerebellar abscess following Craniocervical junction decompression for CIM in a patient with rheumatoid arthritis (RA), which, in our knowledge, is the first described in the literature. We believe that RA and its treatment were major contributors to this complication, mainly due to the immune impairment and the subtle infectious clinical manifestations that they cause. This case led us to modify the perioperative management of patients with RA who undergo spinal surgery in our department. We suggest that strict infection prevention measures should be taken by spine surgeons who treat patients with RA and a high suspicion index for infection should be maintained.
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