作为医学放射学分支的核物理学医学元素学

V. Zaichick, V. Kolotov
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引用次数: 0

摘要

目的:医学元素学及其分支核物理医学元素学作为生物医学科学最重要的领域,作为开发和使用诊断和治疗包括肿瘤在内的各种疾病的新方法的基本依据,仍未被充分纳入医学放射学的武库。为了成功地将核物理医学元素学确立为一门新的科学学科,有必要为其进一步发展制定明确的方法。成果:给出了研究课题的定义和医学元素学的主要假设。说明了化学元素及其放射性同位素和稳定同位素的含量和代谢知识与医学放射学需求之间的密切联系。研究领域包括:1) 化学元素及其放射性同位素和稳定同位素在医学中的应用;2) 器官和组织的可视化以及体内化学元素含量的测定;3) 用核物理方法测定人体组织和体液样本中的化学元素,以解决肿瘤问题;4) 化学元素在计算放射治疗吸收剂量中的作用;5) 用核物理方法确定癌症高危人群。概述了一系列临床实践中可接受的现代核物理分析方法,并将其作为适当的研究工具。说明有必要综合利用核物理分析技术,以获得正常和各种病理情况下人体各器官、组织和体液中化学元素含量的参考值,并对测量进行最严格的质量控制和统一方法。确定了利用核物理学医学元素学成果解决医学放射学问题的现代可能性,并概述了未来的优先事项。结论:核物理化学元素分析方法的稳步发展及其在医学中的应用正在不断扩大医学元素学的可能性范围。这一领域的发展必将为医学放射学未来的成功做出重大贡献。
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Nuclear Physics Medical Elementology as a Section of Medical Radiology
Purpose: Medical elementology and its subsection nuclear physics medical elementology, as the most important areas of biomedical science, are still insufficiently included in the arsenal of medical radiology as a fundamental basis for the development and use of new methods for diagnosing and treating various diseases, including oncological ones. For the successful establishment of nuclear physics medical elementology as a new scientific discipline, it is necessary to develop a clear methodology for its further development. Results: The definition of the subject of research and the main postulates of medical elementology is given. The close interrelation of knowledge about the content and metabolism of chemical elements, as well as their radioactive and stable isotopes, with the needs of medical radiology is shown. The following areas of research are considered: 1) The use of chemical elements, as well as their radioactive and stable isotopes in medicine; 2) Visualization of organs and tissues, as well as in vivo determination of the content of chemical elements in them; 3) Nuclear physical methods for determining chemical elements in samples of tissues and fluids of the human body in solving oncological problems; 4) The role of chemical elements in calculating absorbed doses during radiotherapy; 5) The use of nuclear physical methods in the formation of groups at increased risk of cancer. A range of modern nuclear physics analytical methods acceptable in clinical practice and as an adequate research tool is outlined. The need for the integrated use of nuclear physics analytical technologies to obtain reference values ​​for the content of chemical elements in various organs, tissues and fluids of the human body in normal and various pathological conditions, as well as to organize the strictest quality control of measurements and unify methodological approaches is demonstrated. The modern possibilities of using the achievements of nuclear physics medical elementology in solving the problems of medical radiology are determined and the priorities for the future are outlined. Conclusion: The steady development of nuclear physical methods of chemical elements analysis and their implementation in medicine is constantly expanding the scope of possibilities of medical elementology. The development of this area will certainly make a significant contribution to the future successes of medical radiology.
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来源期刊
Medical Radiology and Radiation Safety
Medical Radiology and Radiation Safety Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
0.40
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0.00%
发文量
72
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