带模块化双头的专用波束内 PET 系统,用于 HIMM 放射治疗成像

Jie Kong, Xibo Zhou, Changxin Wang, Jinda Chen, Genyuan Liang, Chengming Du, Q. She, Yi Qian, Junwei Yan
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摘要

本文介绍了一种重离子束内 PET(简称 ibPET),它配备了专门定制的数据采集系统,该系统在武威重离子医学中心的重离子医学机器(HIMM)束线上构建和测试。多年来,ibPET 的数据采集系统经历了多次升级,其数据处理能力现已超过每通道每秒一百万个事件。为了使ibPET在现有条件下达到最佳性能,我们测试了不同时间重合窗口下的重合事件和噪声等效计数(NEC)。结果表明,当时间窗口在3 ns左右时,重建图像数据的信噪比达到峰值,表明此时ibPET性能最佳。为了确定时间窗的大小,我们测量了系统的时间分辨率 FWHM 为 1.63 ns,最终选择了两倍于时间分辨率 FWHM 的时间窗大小,即 3.25 ns。同时,我们展示了我们的 ibPET 监测各种辐照剂量范围的能力。结果表明,该系统在辐照后呈现出预期的指数衰减计数率,并能准确提供不同能量水平下的穿透深度位置。
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A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM
This paper presents a heavy-ion in-beam PET, referred to as ibPET with a specifically custom designed data acquisition system, which was constructed and tested at the Heavy Ion Medical Machine (HIMM) beam-line, HICTC in Wuwei. The data acquisition system of ibPET has undergone several upgrades during the years, And its data processing capability now exceeds one million events per second per channel. To achieve optimal performance of the ibPET under existing conditions, we tested coincident events and noise equivalent count (NEC) under different time coincidence windows.The results show that the signal-to-noise ratio of the reconstructed image data reaches its peak when the time window is around 3 ns, indicating that the ibPET performance is optimal at this point. In order to determine the size of the time window, we measured the system's time resolution FWHM to be 1.63 ns, and ultimately chose a time window size of twice the time resolution FWHM, which is 3.25 ns. Meanwhile, we demonstrate the capability of our ibPET to monitor the dose range with various irradiation. The results demonstrate that the system exhibits the expected exponential decay in counting rate after irradiation, and accurately provides penetration depth positions at different energy levels.
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