采用分期栓塞和切除术治疗头皮快速生长的先天性播散性化脓性肉芽肿:病例报告

Michael Mohnasky, Jeyhan Wood, Elizabeth Nieman, Jennifer Brondon, Kamran Khan, Kyung Rae Kim
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引用次数: 0

摘要

化脓性肉芽肿是一种常见的后天性血管病变,多为自发性或在以前受过创伤的部位出现。不过,也有少数病例报告了一种罕见的情况,即先天性播散性化脓性肉芽肿(CDPG),婴儿出生时或出生后不久即出现多个化脓性肉芽肿。CDPG 的特征之一是免疫组织化学染色显示葡萄糖转运体 1(GLUT-1)呈阴性,这有助于将其与更常见的多灶性婴儿血管瘤区分开来。由于描述 CDPG 的病例报告很少,人们对其特征、临床过程和最有效的治疗方案还知之甚少。在此,我们介绍了一例表现独特的 CDPG 婴儿病例,该病例的病变异常巨大且生长迅速。我们还介绍了一种通过分期胶栓塞和手术切除治疗 CDPG 大型化脓性肉芽肿的新方法。
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Rapidly Growing Congenital Disseminated Pyogenic Granuloma in the Scalp Treated with Staged Embolization and Excision: A Case Report
Pyogenic granulomas are common, acquired vascular lesions that most often arise spontaneously or in sites of previous trauma. However, there are reports of a few cases that describe a rare condition, congenital disseminated pyogenic granuloma (CDPG), in which an infant either is born with or shortly after birth develops multiple pyogenic granulomas. A hallmark of CDPG is negative staining for glucose transporter 1 (GLUT-1) on immunohistochemistry, which helps distinguish it from the more common multifocal infantile hemangiomas. Because few case reports have described CDPG, much is unknown about its characteristics, clinical course, and most effective treatment options. Here, we present a case of an infant with a unique presentation of CDPG with lesions that are atypically large and growing at a rapid pace. We also describe a novel approach to treating large pyogenic granulomas in CDPG via staged glue embolization and surgical excision.
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