{"title":"患者和亲属的重症监护后综合征。对 COVID-19 和非 COVID-19 组群进行分析,并在三个月和一年后进行面对面随访。","authors":"","doi":"10.1016/j.medin.2024.03.008","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Compare prevalence and profile of post-intensive care patient (P-PICS) and family/caregiver (F-PICS) syndrome in two cohorts (COVID and non-COVID) and analyse risk factors for P-PICS.</p></div><div><h3>Design</h3><p>Prospective, observational cohort (March 2018- 2023), follow-up at three months and one year.</p></div><div><h3>Setting</h3><p>14-bed polyvalent Intensive Care Unit (ICU), Level II Hospital.</p></div><div><h3>Patients or participants</h3><p>265 patients and 209 relatives. Inclusion criteria patients: age<!--> <!-->> 18 years, mechanical ventilation<!--> <!-->> 48<!--> <!-->hours, ICU stay<!--> <!-->> 5 days, delirium, septic shock, acute respiratory distress syndrome, cardiac arrest. Inclusion criteria family: those who attended.</p></div><div><h3>Interventions</h3><p>Follow-up 3 months and 1 year after hospital discharge.</p></div><div><h3>Main variables of interest</h3><p>Patients; sociodemographic, clinical, evolutive, physical, psychological and cognitive alterations, dependency degree and quality of life. Main caregivers: mental state and physical overload.</p></div><div><h3>Results</h3><p>64.9% PICS-P, no differences between groups. COVID patients more physical alterations than non-COVID (p<!--> <!-->=<!--> <!-->0.028). These more functional deterioration (p<!--> <!-->=<!--> <!-->0.005), poorer quality of life (p<!--> <!-->=<!--> <!-->0.003), higher nutritional alterations (p<!--> <!-->=<!--> <!-->0.004) and cognitive deterioration (p<<!--> <!-->0.001). 19.1% PICS-F, more frequent in relatives of non-COVID patients (17.6% vs. 5.5%; p<!--> <!-->=<!--> <!-->0.013). Independent predictors of PICS-P: first years of the study (OR: 0.484), higher comorbidity (OR: 1.158), delirium (OR: 2.935), several reasons for being included (OR: 3.171) and midazolam (OR: 4.265).</p></div><div><h3>Conclusions</h3><p>Prevalence PICS-P and PICS-F between both cohorts was similar. Main factors associated with the development of SPCI-P were: higher comorbidity, delirium, midazolam, inclusion for more than one reason and during the first years.</p></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"48 8","pages":"Pages 445-456"},"PeriodicalIF":2.7000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Síndrome postcuidados intensivos en pacientes y familiares. Análisis de cohortes COVID-19 y no COVID-19, con seguimiento presencial a los tres meses y al año\",\"authors\":\"\",\"doi\":\"10.1016/j.medin.2024.03.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Compare prevalence and profile of post-intensive care patient (P-PICS) and family/caregiver (F-PICS) syndrome in two cohorts (COVID and non-COVID) and analyse risk factors for P-PICS.</p></div><div><h3>Design</h3><p>Prospective, observational cohort (March 2018- 2023), follow-up at three months and one year.</p></div><div><h3>Setting</h3><p>14-bed polyvalent Intensive Care Unit (ICU), Level II Hospital.</p></div><div><h3>Patients or participants</h3><p>265 patients and 209 relatives. Inclusion criteria patients: age<!--> <!-->> 18 years, mechanical ventilation<!--> <!-->> 48<!--> <!-->hours, ICU stay<!--> <!-->> 5 days, delirium, septic shock, acute respiratory distress syndrome, cardiac arrest. Inclusion criteria family: those who attended.</p></div><div><h3>Interventions</h3><p>Follow-up 3 months and 1 year after hospital discharge.</p></div><div><h3>Main variables of interest</h3><p>Patients; sociodemographic, clinical, evolutive, physical, psychological and cognitive alterations, dependency degree and quality of life. Main caregivers: mental state and physical overload.</p></div><div><h3>Results</h3><p>64.9% PICS-P, no differences between groups. COVID patients more physical alterations than non-COVID (p<!--> <!-->=<!--> <!-->0.028). These more functional deterioration (p<!--> <!-->=<!--> <!-->0.005), poorer quality of life (p<!--> <!-->=<!--> <!-->0.003), higher nutritional alterations (p<!--> <!-->=<!--> <!-->0.004) and cognitive deterioration (p<<!--> <!-->0.001). 19.1% PICS-F, more frequent in relatives of non-COVID patients (17.6% vs. 5.5%; p<!--> <!-->=<!--> <!-->0.013). Independent predictors of PICS-P: first years of the study (OR: 0.484), higher comorbidity (OR: 1.158), delirium (OR: 2.935), several reasons for being included (OR: 3.171) and midazolam (OR: 4.265).</p></div><div><h3>Conclusions</h3><p>Prevalence PICS-P and PICS-F between both cohorts was similar. Main factors associated with the development of SPCI-P were: higher comorbidity, delirium, midazolam, inclusion for more than one reason and during the first years.</p></div>\",\"PeriodicalId\":49268,\"journal\":{\"name\":\"Medicina Intensiva\",\"volume\":\"48 8\",\"pages\":\"Pages 445-456\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicina Intensiva\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0210569124000871\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina Intensiva","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0210569124000871","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Síndrome postcuidados intensivos en pacientes y familiares. Análisis de cohortes COVID-19 y no COVID-19, con seguimiento presencial a los tres meses y al año
Objective
Compare prevalence and profile of post-intensive care patient (P-PICS) and family/caregiver (F-PICS) syndrome in two cohorts (COVID and non-COVID) and analyse risk factors for P-PICS.
Design
Prospective, observational cohort (March 2018- 2023), follow-up at three months and one year.
Setting
14-bed polyvalent Intensive Care Unit (ICU), Level II Hospital.
Patients or participants
265 patients and 209 relatives. Inclusion criteria patients: age > 18 years, mechanical ventilation > 48 hours, ICU stay > 5 days, delirium, septic shock, acute respiratory distress syndrome, cardiac arrest. Inclusion criteria family: those who attended.
Interventions
Follow-up 3 months and 1 year after hospital discharge.
Main variables of interest
Patients; sociodemographic, clinical, evolutive, physical, psychological and cognitive alterations, dependency degree and quality of life. Main caregivers: mental state and physical overload.
Results
64.9% PICS-P, no differences between groups. COVID patients more physical alterations than non-COVID (p = 0.028). These more functional deterioration (p = 0.005), poorer quality of life (p = 0.003), higher nutritional alterations (p = 0.004) and cognitive deterioration (p< 0.001). 19.1% PICS-F, more frequent in relatives of non-COVID patients (17.6% vs. 5.5%; p = 0.013). Independent predictors of PICS-P: first years of the study (OR: 0.484), higher comorbidity (OR: 1.158), delirium (OR: 2.935), several reasons for being included (OR: 3.171) and midazolam (OR: 4.265).
Conclusions
Prevalence PICS-P and PICS-F between both cohorts was similar. Main factors associated with the development of SPCI-P were: higher comorbidity, delirium, midazolam, inclusion for more than one reason and during the first years.
期刊介绍:
Medicina Intensiva is the journal of the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC) and of Pan American and Iberian Federation of Societies of Intensive and Critical Care Medicine. Medicina Intensiva has become the reference publication in Spanish in its field. The journal mainly publishes Original Articles, Reviews, Clinical Notes, Consensus Documents, Images, and other information relevant to the specialty. All works go through a rigorous selection process. The journal accepts submissions of articles in English and in Spanish languages. The journal follows the publication requirements of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).