Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502314
Diana Adrião , Marco Pozzi , Silvia Mongodi
{"title":"Ultrasound detection of pulmonary metastatic disease as a cause of acute respiratory failure","authors":"Diana Adrião , Marco Pozzi , Silvia Mongodi","doi":"10.1016/j.medin.2025.502314","DOIUrl":"10.1016/j.medin.2025.502314","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502314"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502313
Mateo Porres-Aguilar , Guillermo Cueto-Robledo
{"title":"Venous thromboembolism prophylaxis in the intensive care unit: Is there a future role for factor XI/XIa inhibitors as novel antithrombotic agents?","authors":"Mateo Porres-Aguilar , Guillermo Cueto-Robledo","doi":"10.1016/j.medin.2025.502313","DOIUrl":"10.1016/j.medin.2025.502313","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502313"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502299
Francisco Ramón Pampín Huerta, Gonzalo Pardo Peña, Dolores Moreira Gómez, María Pilar Madruga Garrido
{"title":"El manejo de la vía aérea en el paciente crítico. Necesidad de adaptar las guías a nuestra realidad y nosotros adherirnos a ellas","authors":"Francisco Ramón Pampín Huerta, Gonzalo Pardo Peña, Dolores Moreira Gómez, María Pilar Madruga Garrido","doi":"10.1016/j.medin.2025.502299","DOIUrl":"10.1016/j.medin.2025.502299","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502299"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502303
Mónica Calviño-Costas , Sofía Bassy Navarro , Inés Leoz Gordillo , Carmen De Lucas Collantes , María Suarez Bustamante , Alberto García-Salido
{"title":"Cardiac arrest in a previously healthy infant caused by secondary pseudohypoaldosteronism: Case report and literature review","authors":"Mónica Calviño-Costas , Sofía Bassy Navarro , Inés Leoz Gordillo , Carmen De Lucas Collantes , María Suarez Bustamante , Alberto García-Salido","doi":"10.1016/j.medin.2025.502303","DOIUrl":"10.1016/j.medin.2025.502303","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502303"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502263
Cinta Millan-Gutierrez , Maria Gil-Arrieta , María Luisa Martínez , Juan Miguel Goyeneche , Maria Dolores Bosque , Francesc Marcano-Fernandez
Objective
To determine what proportion of oral presentations from congresses of the Spanish Society of Intensive care Medicine, Critical care, and Coronary Units (SEMICYUC) are subsequently published in scientific journals.
Design
Observational descriptive study based on the analysis of oral presentations accepted at SEMICYUC congresses every other year from 2013 to 2021, both inclusive.
Setting
National SEMICYUC congresses.
Participants
Abstracts of oral presentations accepted at SEMICYUC congresses every other year from 2013 to 2021.
Main outcome measures
The proportion of published oral presentations is the main outcome. Other outcome measures are time to publication, intensive care subspecialty, journal impact factor and quartile, methodological and design characteristics and funding.
Results
A total of 250 oral presentations were analyzed of which 81 (32.4%) resulted in a publication. «Infection» category had the highest number of oral presentations (64 presentations) and the highest number of published studies (30 publications). Randomized clinical trials (66.7%) and quasi-experimental studies (62.5%) result in the highest publication rates (P = .015). The average journal impact factor is 5.8 (range: 1.2-44.4).
Conclusions
Most abstracts presented as oral presentations at SEMICYUC congresses do not reach publication. Although only 32.4% of these are published, they appear in journals with an average impact factor of 5.8.
{"title":"¿Publicamos lo que presentamos? Análisis de las publicaciones derivadas de los congresos de la SEMICYUC","authors":"Cinta Millan-Gutierrez , Maria Gil-Arrieta , María Luisa Martínez , Juan Miguel Goyeneche , Maria Dolores Bosque , Francesc Marcano-Fernandez","doi":"10.1016/j.medin.2025.502263","DOIUrl":"10.1016/j.medin.2025.502263","url":null,"abstract":"<div><h3>Objective</h3><div>To determine what proportion of oral presentations from congresses of the Spanish Society of Intensive care Medicine, Critical care, and Coronary Units (SEMICYUC) are subsequently published in scientific journals.</div></div><div><h3>Design</h3><div>Observational descriptive study based on the analysis of oral presentations accepted at SEMICYUC congresses every other year from 2013 to 2021, both inclusive.</div></div><div><h3>Setting</h3><div>National SEMICYUC congresses.</div></div><div><h3>Participants</h3><div>Abstracts of oral presentations accepted at SEMICYUC congresses every other year from 2013 to 2021.</div></div><div><h3>Main outcome measures</h3><div>The proportion of published oral presentations is the main outcome. Other outcome measures are time to publication, intensive care subspecialty, journal impact factor and quartile, methodological and design characteristics and funding.</div></div><div><h3>Results</h3><div>A total of 250 oral presentations were analyzed of which 81 (32.4%) resulted in a publication. «Infection» category had the highest number of oral presentations (64 presentations) and the highest number of published studies (30 publications). Randomized clinical trials (66.7%) and quasi-experimental studies (62.5%) result in the highest publication rates (<em>P</em> <!-->=<!--> <!-->.015). The average journal impact factor is 5.8 (range: 1.2-44.4).</div></div><div><h3>Conclusions</h3><div>Most abstracts presented as oral presentations at SEMICYUC congresses do not reach publication. Although only 32.4% of these are published, they appear in journals with an average impact factor of 5.8.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502263"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502216
Daida García Rodríguez , Gabriela Alexandra Narváez Chávez , Sergio Tomás Rodríguez Ramos , Ángel Orera Pérez , Jesús Emilio Barrueco-Francioni , Pedro Merino García , en nombre de los Grupos de Trabajo de Patología Digestiva Crítica y de Hemoterapia, Hematología y Oncología Crítica de la SEMICYUC
Patients with cirrhosis present a highly vulnerable and rebalanced hemostasis state. Assessing the bleeding risk in these patients is complex. It is essential to recognize that conventional coagulation tests do not adequately reflect the true risk of bleeding or thrombosis.
The detailed understanding of this balance and the application of more precise diagnostic tools, such as viscoelastic tests that can more accurately evaluate their coagulation status, facilitate clinical management and can improve the results in these patients.
The haemorrhagic risk of this group of patients is conditioned by specific factors of liver disease, such as portal hypertension and altered haemostatic status, and by systemic factors like the presence of infections and kidney disease, which are independent predictors of bleeding during high-risk procedures. These concepts and the recommendations from the most recent clinical practice guidelines are reviewed in this article.
{"title":"Alteraciones de la coagulación en los pacientes con hepatopatía crónica: una revisión narrativa","authors":"Daida García Rodríguez , Gabriela Alexandra Narváez Chávez , Sergio Tomás Rodríguez Ramos , Ángel Orera Pérez , Jesús Emilio Barrueco-Francioni , Pedro Merino García , en nombre de los Grupos de Trabajo de Patología Digestiva Crítica y de Hemoterapia, Hematología y Oncología Crítica de la SEMICYUC","doi":"10.1016/j.medin.2025.502216","DOIUrl":"10.1016/j.medin.2025.502216","url":null,"abstract":"<div><div>Patients with cirrhosis present a highly vulnerable and rebalanced hemostasis state. Assessing the bleeding risk in these patients is complex. It is essential to recognize that conventional coagulation tests do not adequately reflect the true risk of bleeding or thrombosis.</div><div>The detailed understanding of this balance and the application of more precise diagnostic tools, such as viscoelastic tests that can more accurately evaluate their coagulation status, facilitate clinical management and can improve the results in these patients.</div><div>The haemorrhagic risk of this group of patients is conditioned by specific factors of liver disease, such as portal hypertension and altered haemostatic status, and by systemic factors like the presence of infections and kidney disease, which are independent predictors of bleeding during high-risk procedures. These concepts and the recommendations from the most recent clinical practice guidelines are reviewed in this article.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502216"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502172
Andres Laserna , John A. Cuenca , Peyton Martin , Cosmo Fowler , Julian Barahona-Correa , Nirmala Manjappachar , Clara Fowler , Maria A. Lopez-Olivo , Marcio Borges , Charles L. Sprung , Joseph L. Nates
Objective
We sought to delineate the mortality outcome time frames reported in septic shock randomized control trials (RCTs).
Design
Systematic review of PubMed, EMBASE, and the Cochrane Database of Systematic Reviews.
Setting
Intensive care units.
Participants
Studies that included adult patients with septic shock.
Interventions
Any type of intervention.
Main variables of interest
Information about the study, specific patient population, type of study intervention, specific intervention, and number of patients. Mortality time frames were analyzed for geographical differences and changes over time.
Results
The search yielded 2660 unique citations. After screening, 132 eligible studies were identified. A total of 234 mortality time frames were collected from the included studies, of which 15 timeframes were unique. The most frequently reported time frame was 28-day mortality (n = 98, 74% of trials), followed by hospital mortality (n = 35, 27%), ICU mortality (n = 30, 23%), and 90-day mortality (n = 29, 22%). The most reported mortality time frame was 28 days in studies from every continent except Africa. The studies published between 2008 and 2013 (25%) more frequently reported hospital and ICU mortality combination than studies published between 2014 and 2019 (11.4%) (P = 0.043).
Conclusions
There was considerable variability in the mortality time frames reported in ICU-based septic shock trials. This variability may lead to under or overestimation of the problem, overlooking the effectiveness of the interventions studied, and further limiting the application of trials and their pooling in meta-analyses. A consensus regarding time frame reporting in septic shock trials is long overdue.
{"title":"Mortality time frame variability in septic shock clinical trials: A systematic review","authors":"Andres Laserna , John A. Cuenca , Peyton Martin , Cosmo Fowler , Julian Barahona-Correa , Nirmala Manjappachar , Clara Fowler , Maria A. Lopez-Olivo , Marcio Borges , Charles L. Sprung , Joseph L. Nates","doi":"10.1016/j.medin.2025.502172","DOIUrl":"10.1016/j.medin.2025.502172","url":null,"abstract":"<div><h3>Objective</h3><div>We sought to delineate the mortality outcome time frames reported in septic shock randomized control trials (RCTs).</div></div><div><h3>Design</h3><div>Systematic review of PubMed, EMBASE, and the Cochrane Database of Systematic Reviews.</div></div><div><h3>Setting</h3><div>Intensive care units.</div></div><div><h3>Participants</h3><div>Studies that included adult patients with septic shock.</div></div><div><h3>Interventions</h3><div>Any type of intervention.</div></div><div><h3>Main variables of interest</h3><div>Information about the study, specific patient population, type of study intervention, specific intervention, and number of patients. Mortality time frames were analyzed for geographical differences and changes over time.</div></div><div><h3>Results</h3><div>The search yielded 2660 unique citations. After screening, 132 eligible studies were identified. A total of 234 mortality time frames were collected from the included studies, of which 15 timeframes were unique. The most frequently reported time frame was 28-day mortality (n = 98, 74% of trials), followed by hospital mortality (n = 35, 27%), ICU mortality (n = 30, 23%), and 90-day mortality (n = 29, 22%). The most reported mortality time frame was 28 days in studies from every continent except Africa. The studies published between 2008 and 2013 (25%) more frequently reported hospital and ICU mortality combination than studies published between 2014 and 2019 (11.4%) (<em>P</em> = 0.043).</div></div><div><h3>Conclusions</h3><div>There was considerable variability in the mortality time frames reported in ICU-based septic shock trials. This variability may lead to under or overestimation of the problem, overlooking the effectiveness of the interventions studied, and further limiting the application of trials and their pooling in meta-analyses. A consensus regarding time frame reporting in septic shock trials is long overdue.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502172"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502350
Susana Reyes-Domínguez , Ana Abril-Molina , Raúl Montero-Yéboles , Vicente Modesto i Alapont
Pediatric acute respiratory distress syndrome (PARDS) is the clinical expression of severe non-cardiogenic pulmonary edema.
The agreed-upon definition shares common criteria with that for adults but also includes differences determined by the child's idiosyncrasy. The definition of PARDS does not require bilateral infiltrates on the chest x-ray; hypoxemia can be identified noninvasively using the blood oxygen saturation/fraction of inspired oxygen (S/F) ratio; it is stratified into two groups (mild-moderate and severe) after a stabilization period of at least 4 hours; and the oxygenation index and the oxygenation-saturation ratio are used in intubated patients.
Optimized respiratory support settings should prevent lung injury and allow for early identification of patients requiring extracorporeal membrane oxygenation (ECMO). This article seeks to conduct a critical analysis of PARS. Accurate diagnose of this syndrome remains a challenge.
{"title":"Síndrome de distrés respiratorio agudo en el paciente crítico pediátrico","authors":"Susana Reyes-Domínguez , Ana Abril-Molina , Raúl Montero-Yéboles , Vicente Modesto i Alapont","doi":"10.1016/j.medin.2025.502350","DOIUrl":"10.1016/j.medin.2025.502350","url":null,"abstract":"<div><div>Pediatric acute respiratory distress syndrome (PARDS) is the clinical expression of severe non-cardiogenic pulmonary edema.</div><div>The agreed-upon definition shares common criteria with that for adults but also includes differences determined by the child's idiosyncrasy. The definition of PARDS does not require bilateral infiltrates on the chest x-ray; hypoxemia can be identified noninvasively using the blood oxygen saturation/fraction of inspired oxygen (S/F) ratio; it is stratified into two groups (mild-moderate and severe) after a stabilization period of at least 4<!--> <!-->hours; and the oxygenation index and the oxygenation-saturation ratio are used in intubated patients.</div><div>Optimized respiratory support settings should prevent lung injury and allow for early identification of patients requiring extracorporeal membrane oxygenation (ECMO). This article seeks to conduct a critical analysis of PARS. Accurate diagnose of this syndrome remains a challenge.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502350"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1016/j.medin.2025.502255
Carmen Huertas Marín , Trinidad Dierssen-Soto , Yhivian Peñasco , Elena Cuenca-Fito , Reinhard Wallmann , Raquel Ferrero-Franco , Juan Carlos Rodríguez-Borregán , Alejandro González-Castro
Objective
To analyse which variables associated with ICU admission for COVID-19 were linked to higher hospital costs according to the APR-DRG classification.
Design
Retrospective, observational, and analytical study.
Setting
COVID-19 ICU in a tertiary hospital.
Patients
Adults (> 18 years) with a confirmed diagnosis of SARS-CoV-2 infection.
Interventions
Predictive models using multiple logistic regression.
Main variables of interest
Hospital cost, APR-DRG, mechanical ventilation.
Results
A total of 799 patients were analysed and categorized into tertiles based on hospital stay costs, resulting in 3 groups: 266 patients with lower costs (median € 6,160 [p25: 3,962-p75: 6,160]), 314 with intermediate costs (median € 16,446 [p25: 10,653-p75: 18,274]), and 219 with higher costs (median € 26,085 [p25: 26,085-p75: 51,523]). The best predictive model, with an AIC of 490.09 and an R2 of 0.32, identified the following factors as significantly associated with higher hospital costs: ICU length of stay (OR: 1.05; 95% CI: 1.03-1.07; p < 0.01), development of VAT/VAP (OR: 4.72; 95% CI: 2.83-7.85; p < 0.01), OXA-48 infection (OR: 2.65; 95% CI: 1.25-5.61; p = 0.01), pulmonary embolism (OR: 6.42; 95% CI: 2.17-19.26; p < 0.01), smoking history (OR: 2.22; 95% CI: 1.49-3.74; p < 0.01), and vasopressor requirement (OR: 1.79; 95% CI: 1.22-2.86; p = 0.01). The area under the curve was 0.866 (p < 0.01).
Conclusions
Prolonged ICU stay, infectious and thromboembolic complications, smoking history, and vasopressor requirement were significantly associated with higher hospital costs.
{"title":"Modelo de regresión logística para predecir el mayor coste hospitalario en los enfermos que ingresaron en UCI-COVID durante la pandemia. Resultados en un hospital de tercer nivel","authors":"Carmen Huertas Marín , Trinidad Dierssen-Soto , Yhivian Peñasco , Elena Cuenca-Fito , Reinhard Wallmann , Raquel Ferrero-Franco , Juan Carlos Rodríguez-Borregán , Alejandro González-Castro","doi":"10.1016/j.medin.2025.502255","DOIUrl":"10.1016/j.medin.2025.502255","url":null,"abstract":"<div><h3>Objective</h3><div>To analyse which variables associated with ICU admission for COVID-19 were linked to higher hospital costs according to the APR-DRG classification.</div></div><div><h3>Design</h3><div>Retrospective, observational, and analytical study.</div></div><div><h3>Setting</h3><div>COVID-19 ICU in a tertiary hospital.</div></div><div><h3>Patients</h3><div>Adults (><!--> <!-->18 years) with a confirmed diagnosis of SARS-CoV-2 infection.</div></div><div><h3>Interventions</h3><div>Predictive models using multiple logistic regression.</div></div><div><h3>Main variables of interest</h3><div>Hospital cost, APR-DRG, mechanical ventilation.</div></div><div><h3>Results</h3><div>A total of 799 patients were analysed and categorized into tertiles based on hospital stay costs, resulting in 3 groups: 266 patients with lower costs (median €<!--> <!-->6,160 [p25: 3,962-p75: 6,160]), 314 with intermediate costs (median €<!--> <!-->16,446 [p25: 10,653-p75: 18,274]), and 219 with higher costs (median €<!--> <!-->26,085 [p25: 26,085-p75: 51,523]). The best predictive model, with an AIC of 490.09 and an R<sup>2</sup> of 0.32, identified the following factors as significantly associated with higher hospital costs: ICU length of stay (OR: 1.05; 95% <span>C</span>I: 1.03-1.07; <em>p</em> <!--><<!--> <!-->0.01), development of VAT/VAP (OR: 4.72; 95% CI: 2.83-7.85; <em>p</em> <!--><<!--> <!-->0.01), OXA-48 infection (OR: 2.65; 95% CI: 1.25-5.61; <em>p</em> <!-->=<!--> <!-->0.01), pulmonary embolism (OR: 6.42; 95% CI: 2.17-19.26; <em>p</em> <!--><<!--> <!-->0.01), smoking history (OR: 2.22; 95% CI: 1.49-3.74; <em>p</em> <!--><<!--> <!-->0.01), and vasopressor requirement (OR: 1.79; 95% CI: 1.22-2.86; <em>p</em> <!-->=<!--> <!-->0.01). The area under the curve was 0.866 (<em>p</em> <!--><<!--> <!-->0.01).</div></div><div><h3>Conclusions</h3><div>Prolonged ICU stay, infectious and thromboembolic complications, smoking history, and vasopressor requirement were significantly associated with higher hospital costs.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"50 2","pages":"Article 502255"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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