奥兰大学医院肾移植的药物经济学评估:成本分析及影响

Mohamed Sadeg Amine Amarni, H. Fetati, Kada Djoudad, B. Bendifallah, F. Zerdoumi, H. Toumi
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摘要

导言2019 年,阿尔及利亚接受透析治疗的患者人数预计为 23798 人。肾移植是终末期肾病(ESKD)患者的最佳治疗选择。然而,这种手术费用昂贵,而且需要复杂的管理。本研究旨在评估阿尔及利亚奥兰大学医院(UHEO)肾移植手术的相关费用。材料和方法对在奥兰大学医院接受肾移植手术的 31 名患者进行了回顾性、描述性、单中心研究。估算的费用包括移植前检查、移植后立即住院、移植后随访和并发症处理所需的药物、耗材、成像和实验室检测费用。结果移植准备的平均费用为 485 438.31 阿尔及利亚第纳尔(DZD)。移植后立即住院的平均费用为 375 484.70 第纳尔。移植后第一年的费用最高,平均费用为 1,305,197.40 第纳尔,主要用于治疗、住院、临床和辅助检查。研究还显示,随着移植年龄的增长和受者临床病情的稳定,费用呈下降趋势。
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Évaluation pharmaco-économique de la transplantation rénale à l’établissement hospitalier et universitaire d’Oran : analyse des coûts et implications
Introduction In Algeria, the number of patients treated by dialysis is estimated at 23,798 in 2019. Kidney transplantation is the best therapeutic option for patients suffering from end stage kidney Disease (ESKD). However, this procedure is costly and requires complex management. The aim of this study is to assess the costs associated with kidney transplantation at the University Hospital Establishment of Oran, Algeria (UHEO). Materials and methods A retrospective, descriptive, monocentric study was carried out on 31 patients who underwent kidney transplantation at the UHEO. Estimated costs included drugs, consumables, imaging and laboratory tests for pre-transplant examinations, immediate post-transplant hospitalization, post-transplant follow-up and management of any complications. Results The average cost of graft preparation was 485,438.31 Algerian Dinar (DZD). Immediate post-transplant hospitalization represented an average cost of 375,484.70 DZD. The first year post-transplantation was the most costly with an average cost of 1,305,197.40 DZD mainly attributed to treatment, hospitalization, clinical and paraclinical examinations. Conclusion This study estimated the cost of kidney transplantation at the UHEO and revealed that the cost of the first year is the most important due to many factors. It also showed that costs tend to decrease with the age of the transplant and the clinical stability of the recipient.
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