论混合基因调控网络

Adrian Wurm, Honglu Sun
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引用次数: 0

摘要

在这项工作中,我们研究了一类称为混合基因调控网络(HGRNs)的混合动力系统,该系统是为模拟基因调控网络而提出的。在混合基因调控网络中,既存在达到定点或收敛到极限循环的良好轨迹,也存在非周期性或不确定性的混乱轨迹。在我们的工作中,我们研究了 HGRN 的这些不规则行为,并提出了关于可达性问题的可判定性、HGRN 不确定行为的概率以及混沌(尤其是二维 HGRN 中的混沌)的理论结果。
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On Hybrid Gene Regulatory Networks
In this work, we study a class of hybrid dynamical systems called hybrid gene regulatory networks (HGRNs) which was proposed to model gene regulatory networks. In HGRNs, there exist well-behaved trajectories that reach a fixed point or converge to a limit cycle, as well as chaotic trajectories that behave non-periodic or indeterministic. In our work, we investigate these irregular behaviors of HGRNs and present theoretical results about the decidability of the reachability problem, the probability of indeterministic behavior of HGRNs, and chaos especially in 2-dimensional HGRNs.
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