在聚乳酸膜表面沉积类金刚石碳以防止肌腱修复过程中的粘连形成

IF 26.6 1区材料科学 Q1 Engineering Nano-Micro Letters Pub Date : 2024-04-30 DOI:10.1007/s40820-024-01392-7

Yao Xiao, Zaijin Tao, Yufeng Ju, Xiaolu Huang, Xinshu Zhang, Xiaonan Liu, Pavel A. Volotovski, Chao Huang, Hongqi Chen, Yaozhong Zhang, Shen Liu

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引用次数: 0

摘要

沉积了类金刚石碳（DLC）的聚乳酸（PLA）膜的抗粘连效果为44.72%，与PLA相比提高了23.11%。事实证明，在聚乳酸膜上沉积类金刚石碳可有效降低活性氧水平，从而减少腱周粘连组织中促炎细胞因子的表达。

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Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair

The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA.
DLC deposited on PLA membranes has been shown to effectively reduce the levels of reactive oxygen species, leading to a decrease in the expression of pro-inflammatory cytokines within peritendinous adhesion tissue.
DLC decelerates PLA biodegradation and lactic production, which reduces the number of CD68⁺CD206⁺ macrophages within peritendinous adhesion tissue.

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来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

32.60

自引率

4.90%

发文量

981

审稿时长

1.1 months

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary, and open-access journal published under the SpringerOpen brand. Nano-Micro Letters focuses on the science, experiments, engineering, technologies, and applications of nano- or microscale structures and systems in various fields such as physics, chemistry, biology, material science, and pharmacy.It also explores the expanding interfaces between these fields. Nano-Micro Letters particularly emphasizes the bottom-up approach in the length scale from nano to micro. This approach is crucial for achieving industrial applications in nanotechnology, as it involves the assembly, modification, and control of nanostructures on a microscale.