骨科肿瘤学的争议。

Lee M Jeys, Joachim Thorkildsen, Vineet Kurisunkal, Ajay Puri, Pietro Ruggieri, Matthew T Houdek, Richard A Boyle, Walid Ebeid, Eduardo Botello, Guy V Morris, , Minna K Laitinen, , Adesegun Abudu, Keisuke Ae, Manish Agarwal, Vivek Ajit Singh, Toru Akiyama, Jose I Albergo, John Alexander, Bugra Alpan, Ahmed Aoude, Apichat Asavamongkolkul, William Aston, Thomas Baad-Hansen, Tessa Balach, Joseph Benevenia, Peter Bergh, Nicholas Bernthal, Odion Binitie, Michele Boffano, Jos Bramer, Harriet Branford White, Bernadette Brennan, Jorge Cabrolier, Jose A Calvo Haro, Domenico A Campanacci, Rodrigo Cardoso, Richard Carey Smith, Nicolas Casales Fresnga, Jose M Casanova, Oscar Ceballos, Chung M Chan, Yang-Guk Chung, Miguel A Clara-Altamirano, Gillian Cribb, Solomon Dadia, Dietmar Dammerer, Marieke de Vaal, Javier Delgado Obando, Shaneel Deo, Claudia Di Bella, Davide M Donati, Makoto Endo, Levent Eralp, Bulent Erol, Scott Evans, Will Eward, Fabrice Fiorenza, Joao Freitas, Philipp T Funovics, Marcos Galli Serra, Michelle Ghert, Kanishka Ghosh, Luis C Gomez Mier, Jesus Gomez Vallejo, Anthony Griffin, Ashish Gulia, Maurice Guzman, Jendrik Hardes, John Healey, Adriana Hernandez, Asle Hesla, Chindanai Hongsaprabhas, Francis Hornicek, Keith Hosking, Shintaro Iwata, Jake Jagiello, Luke Johnson, Andy Johnston, Min Wook Joo, Paul Jutte, Bilal Kapanci, Zeeshan Khan, Hiroshi Kobayashi, Yehuda Kollender, Sebastian Koob, Daniel Kotrych, Louis-Romee Le Nail, Pawel Legosz, Burkhard Lehner, Andreas Leithner, Valerae Lewis, Peng Lin, Francisco Linares, Santiago Lozano Calderon, Ashish Mahendra, Ferdiansyah Mahyudin, Eric Mascard, Jean-Camille Mattei, Louise McCullough, Manuel R Medellin Rincon, Rhidian Morgan-Jones, Diego J Moriel Garcesco, Sophie Mottard, Robert Nakayama, Prashant Narhari, Gary O'Toole, Oliveira Vania, André Olivier, Mohamed Omar, Eduardo Ortiz-Cruz, Harzem Ozger, Korhan Ozkan, Emanuela Palmerini, Panayiotis Papagelopoulos, Michael Parry, Sam Patton, Michael M Petersen, Gerard Powell, Mark Puhaindran, Anand Raja, Raja B Rajasekaran, Lauris Repsa, Mickael Ropars, Andrea Sambri, Thomas Schubert, Ahmad Shehadeh, Geoffrey Siegel, Scott Sommerville, Andre Spiguel, Jonathan Stevenson, Gwen Sys, Thomas Temple, Frank Traub, Hiroyuki Tsuchiya, Juan Valencia, Michel Van de Sande, Gualter Vaz, Roberto Velez Villa, Oleg Vyrva, Hazem Wafa, Wan I Wan Faisham Numan, Edward Wang, David Warnock, Joel Werier, Kwok-Chuen Wong, Yamamoto Norio, Ye Zhaoming, Suraya Zainul Abidin, Tomas Zamora, Juan P Zumarraga, Ghaith Abou-Nouar, Carsten Gebert, R L Randall
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引用次数: 0

摘要

软骨肉瘤是第二大最常见的手术治疗原发性骨肉瘤。尽管文献中有大量科学论文,但在诊断、原发性肿瘤的治疗、亚型和并发症等方面仍存在很大争议。因此,需要就其日常治疗决策达成共识。2024 年 1 月,伯明翰骨科肿瘤学会议(BOOM)试图与来自 50 多个国家的 300 名代表达成全球共识。会议重点关注这些关键领域,旨在根据不同地区的证据汇总和专家意见形成共识声明。与此同时,由于辅助治疗、大面积暴露和手术的复杂性等因素,肿瘤重建中的假体周围关节感染(PJI)带来了独特的挑战。会议讨论了两阶段翻修、抗生素预防、化疗患者急性 PJI 的管理以及伤口管理和异体移植重建最佳策略的定义。会议的目标不仅仅是解决眼前的争议。会议旨在促进与会专家之间的全球合作,并鼓励未来的研究项目解决尚未解决的难题。通过强调存在分歧的领域和促进合作研究努力,该倡议旨在提高治疗标准,并有可能改善全球患者的治疗效果。本文列出了会议上讨论的一些争议和问题。
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Controversies in orthopaedic oncology.
Chondrosarcoma is the second most common surgically treated primary bone sarcoma. Despite a large number of scientific papers in the literature, there is still significant controversy about diagnostics, treatment of the primary tumour, subtypes, and complications. Therefore, consensus on its day-to-day treatment decisions is needed. In January 2024, the Birmingham Orthopaedic Oncology Meeting (BOOM) attempted to gain global consensus from 300 delegates from over 50 countries. The meeting focused on these critical areas and aimed to generate consensus statements based on evidence amalgamation and expert opinion from diverse geographical regions. In parallel, periprosthetic joint infection (PJI) in oncological reconstructions poses unique challenges due to factors such as adjuvant treatments, large exposures, and the complexity of surgery. The meeting debated two-stage revisions, antibiotic prophylaxis, managing acute PJI in patients undergoing chemotherapy, and defining the best strategies for wound management and allograft reconstruction. The objectives of the meeting extended beyond resolving immediate controversies. It sought to foster global collaboration among specialists attending the meeting, and to encourage future research projects to address unsolved dilemmas. By highlighting areas of disagreement and promoting collaborative research endeavours, this initiative aims to enhance treatment standards and potentially improve outcomes for patients globally. This paper sets out some of the controversies and questions that were debated in the meeting.
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