Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0526.r1
Natalie Green,James E Archer,Charles A E Baird,Scott Evans
AimsThe aim of this study was to assess the presentation, investigation and management of patients with a clear cell sarcoma within a single-centre, tertiary bone tumour unit, reporting the rates of survival, local recurrence, and metastases.MethodsThe study involved a retrospective review of a prospectively maintained oncology database, from which we identified and included 47 patients who were referred and treated for a clear cell soft-tissue sarcoma at our unit between January 1996 and January 2024. The median follow-up was 28 months (IQR 13.5 to 71.5). The primary outcome measure was survival and secondary outcomes included the rates of local recurrence and the development of metastases.ResultsThe overall survival for all patients was 61.9% at two years (95% CI 49.1 to 78.1), 45.7% at five years (95% CI 32.6 to 64.1), and 37.4% at ten years (95% CI 24.1 to 57.9). The median survival was 40 months. At the time of presentation, metastases were found in 13 patients (28%), in whom radionuclide imaging with positron emission tomography (PET) CT allowed better identification. More than half of the patients who were referred from elsewhere had prviously undergone an unplanned excision, although this did not seem to influence the mortality outcomes. Excision of the tumour and/or local disease was the primary treatment, with curative intent in 37 patients (78.7%). Local recurrence and metastases after the primary treatment was noted in seven (19%) and 16 (43%) patients, respectively, with a wide range of timing (1 to 73 months). Primary excision with disease-free margins gave the best chance of cure.ConclusionClear cell sarcoma is an aggressive tumour. The rate of survival remains modest. The early identification of metastases using PET CT allowed for more focused treatment. The local follow-up protocol must appreciate the wide variations in the time to recurrence. Targeted immunological systemic treatments may improve the outcomes in the future.
目的本研究的目的是评估单一中心三级骨肿瘤单位内透明细胞肉瘤患者的表现、调查和治疗,报告生存率、局部复发率和转移率。方法:本研究对前瞻性维护的肿瘤学数据库进行回顾性审查,从中我们确定并纳入了1996年1月至2024年1月期间在我们单位转诊并治疗透明细胞软组织肉瘤的47例患者。中位随访28个月(IQR 13.5 ~ 71.5)。主要结局指标是生存,次要结局包括局部复发率和转移的发展。结果所有患者的2年总生存率为61.9% (95% CI 49.1 ~ 78.1), 5年生存率为45.7% (95% CI 32.6 ~ 64.1), 10年生存率为37.4% (95% CI 24.1 ~ 57.9)。中位生存期为40个月。在表现时,13例患者(28%)发现转移,其中放射性核素成像与正电子发射断层扫描(PET) CT可以更好地识别。从其他地方转来的病人中,有一半以上以前做过计划外的切除手术,尽管这似乎并不影响死亡率结果。切除肿瘤和/或局部疾病是主要治疗方法,37例患者(78.7%)有治愈意图。原发性治疗后局部复发和转移分别发生在7例(19%)和16例(43%)患者中,时间范围很广(1至73个月)。无病边缘的原发性切除是治愈的最佳机会。结论透明细胞肉瘤是一种侵袭性肿瘤。生存率仍然不高。使用PET CT早期识别转移允许更集中的治疗。局部随访方案必须考虑到复发时间的广泛差异。靶向免疫系统治疗可能会改善未来的结果。
{"title":"Clear cell sarcoma : a retrospective review from a tertiary orthopaedic sarcoma unit.","authors":"Natalie Green,James E Archer,Charles A E Baird,Scott Evans","doi":"10.1302/0301-620x.108b2.bjj-2025-0526.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0526.r1","url":null,"abstract":"AimsThe aim of this study was to assess the presentation, investigation and management of patients with a clear cell sarcoma within a single-centre, tertiary bone tumour unit, reporting the rates of survival, local recurrence, and metastases.MethodsThe study involved a retrospective review of a prospectively maintained oncology database, from which we identified and included 47 patients who were referred and treated for a clear cell soft-tissue sarcoma at our unit between January 1996 and January 2024. The median follow-up was 28 months (IQR 13.5 to 71.5). The primary outcome measure was survival and secondary outcomes included the rates of local recurrence and the development of metastases.ResultsThe overall survival for all patients was 61.9% at two years (95% CI 49.1 to 78.1), 45.7% at five years (95% CI 32.6 to 64.1), and 37.4% at ten years (95% CI 24.1 to 57.9). The median survival was 40 months. At the time of presentation, metastases were found in 13 patients (28%), in whom radionuclide imaging with positron emission tomography (PET) CT allowed better identification. More than half of the patients who were referred from elsewhere had prviously undergone an unplanned excision, although this did not seem to influence the mortality outcomes. Excision of the tumour and/or local disease was the primary treatment, with curative intent in 37 patients (78.7%). Local recurrence and metastases after the primary treatment was noted in seven (19%) and 16 (43%) patients, respectively, with a wide range of timing (1 to 73 months). Primary excision with disease-free margins gave the best chance of cure.ConclusionClear cell sarcoma is an aggressive tumour. The rate of survival remains modest. The early identification of metastases using PET CT allowed for more focused treatment. The local follow-up protocol must appreciate the wide variations in the time to recurrence. Targeted immunological systemic treatments may improve the outcomes in the future.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"30 1","pages":"234-240"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2024-1360.r3
Petar Golijanin,Paolo Spinello,Fabrizio Brindisino,Nicola de Gasperis,Leonardo Moreno Rodriguez,Matthew T Provencher,Giovanni Di Giacomo
AimsNumerous studies have identified risk factors for recurrent anterior shoulder dislocation, but the exact impact of each remains unclear. This study analyzes outcomes after arthroscopic bony Bankart repair (ABBR) and evaluates how time to surgery, number of preoperative instability events, age, glenoid bone loss (GBL), glenoid bone fragment (GBF), age at surgery, and preoperative Western Ontario Shoulder Instability (WOSI) scores influence recurrence.MethodsA retrospective review was conducted of patients who underwent ABBR between January 2008 and December 2018. Data included demographic details, number of instability episodes, time to surgery, age at first dislocation, GBL, GBF size, WOSI scores, and recurrence rates.ResultsA total of 243 patients with bony Bankart lesions were included. The mean age was 25.4 years (17 to 46). Recurrence occurred in 24 patients (9.9%). Compared with the non-recurrence group, patients with recurrence had smaller GBF (6.5% (SD 4.2) vs 8.8% (SD 5.6); p = 0.049), longer elapsed time since initial instability (20.0 months vs 13.2 months; p < 0.001), younger age at initial instability (21.9 years (SD 6.9) vs 25.6 years (SD 5.2); p = 0.002), and more preoperative instability events (5.7 (SD 3.1) vs 3.8 (SD 2.0); p < 0.001). Postoperative WOSI scores improved in both groups but were not significantly different (447 (SD 141) vs 381 (SD 98)). Regression analysis showed that older age, larger GBF, and lower GBL were independently associated with reduced recurrence risk.ConclusionPatients without recurrence were generally older, had shorter delay from the initial instability event, fewer preoperative instability events, and larger GBF for incorporation in the repair. In younger patients, smaller GBF and greater GBL were strongly associated with recurrence. These findings indicate that the longer the elapsed time, the greater the reabsorption of the glenoid bone fragment and, consequently, the greater the glenoid bone loss. Therefore, strategies aimed at preserving fragment size, potentially through timely surgical intervention, may help reduce recurrence. In patients aged over 40 years, GBL and GBF did not confer the same recurrence risk. Further studies are needed to clarify the thresholds for elapsed time and number of instability events that significantly affect recurrence after ABBR.
目的许多研究已经确定了复发性肩前脱位的危险因素,但每个因素的确切影响尚不清楚。本研究分析了关节镜下骨Bankart修复(ABBR)后的结果,并评估了手术时间、术前不稳定事件数量、年龄、盂骨丢失(GBL)、盂骨碎片(GBF)、手术年龄和术前西安大略省肩部不稳定(WOSI)评分对复发的影响。方法回顾性分析2008年1月至2018年12月接受ABBR手术的患者。数据包括人口统计学细节、不稳定发作次数、手术时间、首次脱位年龄、GBL、GBF大小、WOSI评分和复发率。结果共纳入243例骨性Bankart病变患者。平均年龄为25.4岁(17 ~ 46岁)。复发24例(9.9%)。与未复发组相比,复发患者的GBF较小(6.5% (SD 4.2) vs 8.8% (SD 5.6);p = 0.049),初始不稳定发生时间较长(20.0个月vs 13.2个月,p < 0.001),初始不稳定发生时年龄较小(21.9年(SD 6.9) vs 25.6年(SD 5.2);p = 0.002),以及更多的术前不稳定事件(5.7 (SD 3.1) vs 3.8 (SD 2.0);P < 0.001)。两组术后WOSI评分均有改善,但差异无统计学意义(447 (SD 141) vs 381 (SD 98))。回归分析显示,年龄越大、GBF越大和GBL越低与复发风险降低独立相关。结论无复发患者一般年龄较大,从初始不稳定事件延迟时间较短,术前不稳定事件较少,纳入修复的GBF较大。在年轻患者中,较小的GBF和较大的GBL与复发密切相关。这些结果表明,时间越长,肩关节骨碎片的重吸收越大,因此肩关节骨损失越大。因此,旨在保持碎片大小的策略,可能通过及时的手术干预,有助于减少复发。在40岁以上的患者中,GBL和GBF没有相同的复发风险。需要进一步的研究来明确对ABBR术后复发有显著影响的不稳定事件的时间和数量的阈值。
{"title":"Age, glenoid bone fragment, and glenoid bone loss increase recurrence risk after arthroscopic bony Bankart repair.","authors":"Petar Golijanin,Paolo Spinello,Fabrizio Brindisino,Nicola de Gasperis,Leonardo Moreno Rodriguez,Matthew T Provencher,Giovanni Di Giacomo","doi":"10.1302/0301-620x.108b2.bjj-2024-1360.r3","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2024-1360.r3","url":null,"abstract":"AimsNumerous studies have identified risk factors for recurrent anterior shoulder dislocation, but the exact impact of each remains unclear. This study analyzes outcomes after arthroscopic bony Bankart repair (ABBR) and evaluates how time to surgery, number of preoperative instability events, age, glenoid bone loss (GBL), glenoid bone fragment (GBF), age at surgery, and preoperative Western Ontario Shoulder Instability (WOSI) scores influence recurrence.MethodsA retrospective review was conducted of patients who underwent ABBR between January 2008 and December 2018. Data included demographic details, number of instability episodes, time to surgery, age at first dislocation, GBL, GBF size, WOSI scores, and recurrence rates.ResultsA total of 243 patients with bony Bankart lesions were included. The mean age was 25.4 years (17 to 46). Recurrence occurred in 24 patients (9.9%). Compared with the non-recurrence group, patients with recurrence had smaller GBF (6.5% (SD 4.2) vs 8.8% (SD 5.6); p = 0.049), longer elapsed time since initial instability (20.0 months vs 13.2 months; p < 0.001), younger age at initial instability (21.9 years (SD 6.9) vs 25.6 years (SD 5.2); p = 0.002), and more preoperative instability events (5.7 (SD 3.1) vs 3.8 (SD 2.0); p < 0.001). Postoperative WOSI scores improved in both groups but were not significantly different (447 (SD 141) vs 381 (SD 98)). Regression analysis showed that older age, larger GBF, and lower GBL were independently associated with reduced recurrence risk.ConclusionPatients without recurrence were generally older, had shorter delay from the initial instability event, fewer preoperative instability events, and larger GBF for incorporation in the repair. In younger patients, smaller GBF and greater GBL were strongly associated with recurrence. These findings indicate that the longer the elapsed time, the greater the reabsorption of the glenoid bone fragment and, consequently, the greater the glenoid bone loss. Therefore, strategies aimed at preserving fragment size, potentially through timely surgical intervention, may help reduce recurrence. In patients aged over 40 years, GBL and GBF did not confer the same recurrence risk. Further studies are needed to clarify the thresholds for elapsed time and number of instability events that significantly affect recurrence after ABBR.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"93 1","pages":"202-208"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0629.r1
Hanne-Eva van Bremen,Lotta J Seppala,Nathalie van der Velde,Johannes H Hegeman,Hanna C Willems, , ,Wilco P Achterberg,Frank Malgo,Agneta H Calf-de Bruin,Pim W van Egmond,Elvira R Flikweert,Martin J Heetveld,Johannes H Hegeman,Bernard G Schutte,Marijke C Trappenburg,Stijn C Voeten,Frans J G Wijdicks,Franka S Würdemann,Cornelis L P van de Ree, ,G De Klerk,C Stevens,J Snoek,H A F Luning,D Van der Velde,E J Verleisdonk,A H P Niggebrugge,M Regtuijt,F Wurdemann
AimsThis study examined the association between post-admission complications and 120-day mortality using data from a national hip fracture registry. A sub-analysis explored the impact of improved complication registration on these associations.MethodsWe conducted a cohort study including patients (1 January 2018 to 31 December 2023) from the Dutch Hip Fracture Audit (DHFA). Ten complications (anaemia, delirium, fall incident, heart failure, pneumonia, pressure ulcer, pulmonary embolism (PE), renal dysfunction, urinary tract infection, wound infection) were assessed. From 2018 to 2019, seven hospitals were recruited for additional data collection for the DHFA to improve and develop quality indicators. A multivariate Cox regression model was used to calculate the hazard ratio (HR) between complications and mortality at 30, 60, and 120 days. Subgroup analysis assessed the effect of better registration.ResultsA total of 86,524 patients were included, with a median age of 81 years (IQR 72 to 87). The overall complication rate was 25.7% (n = 22,210), anaemia was the most common complication (n = 8,027; 9.3%), followed by delirium (n = 7,836; 9.1%). In subgroup analysis, project hospitals had a higher overall complications rate (38.8% vs 27.4%; p < 0.001). After adjustment for confounders, at 30 days, heart failure (HR 2.45 (95% CI 2.15 to 2.75)), delirium (HR 1.28 (95% CI 1.19 to 1.38)), PE (HR 2.62 (95% CI 2.11 to 3.27)), renal dysfunction (HR 2.20 (95% CI 1.96 to 2.47)), and pneumonia (HR 2.35 (95% CI 2.15 to 2.56)) were significantly associated with an increased hazard of death. In the subgroup analysis, fewer complications were associated with an increased hazard of death in the project hospitals in comparison to the non-project hospitals.ConclusionFive complications were significantly associated with an increased risk of mortality at 30 and 60 days. These findings highlight the importance of closely monitoring and managing complications. Improved registration practices in project hospitals were linked to fewer complications that showed a relation with mortality. Complications without a clear association with mortality may be more suitable for short-cycle in-hospital feedback rather than a national audit.
目的:本研究利用国家髋部骨折登记处的数据,研究入院后并发症与120天死亡率之间的关系。子分析探讨了改善并发症登记对这些关联的影响。方法:我们进行了一项队列研究,包括来自荷兰髋部骨折审计(DHFA)的患者(2018年1月1日至2023年12月31日)。观察10例并发症(贫血、谵妄、跌倒、心力衰竭、肺炎、压疮、肺栓塞、肾功能不全、尿路感染、伤口感染)。从2018年到2019年,招募了7家医院为DHFA收集更多数据,以改进和制定质量指标。采用多变量Cox回归模型计算30,60和120天并发症与死亡率之间的风险比(HR)。亚组分析评估了更好的登记效果。结果共纳入86524例患者,中位年龄81岁(IQR 72 ~ 87)。总并发症发生率为25.7% (n = 22210),其中最常见的并发症为贫血(n = 8027, 9.3%),其次为谵妄(n = 7836, 9.1%)。亚组分析中,项目医院的总并发症发生率较高(38.8% vs 27.4%; p < 0.001)。调整混杂因素后,在30天,心力衰竭(危险度2.45 (95% CI 2.15至2.75))、谵妄(危险度1.28 (95% CI 1.19至1.38))、PE(危险度2.62 (95% CI 2.11至3.27))、肾功能障碍(危险度2.20 (95% CI 1.96至2.47))和肺炎(危险度2.35 (95% CI 2.15至2.56))与死亡风险增加显著相关。在亚组分析中,与非项目医院相比,项目医院的并发症较少,死亡风险增加。结论5种并发症与30d和60d死亡风险显著相关。这些发现强调了密切监测和管理并发症的重要性。改进项目医院的登记做法可减少与死亡率有关的并发症。与死亡率没有明确关联的并发症可能更适合于短周期的住院反馈,而不是国家审计。
{"title":"Association between ten complications and mortality : insights from the Dutch Hip Fracture Audit.","authors":"Hanne-Eva van Bremen,Lotta J Seppala,Nathalie van der Velde,Johannes H Hegeman,Hanna C Willems, , ,Wilco P Achterberg,Frank Malgo,Agneta H Calf-de Bruin,Pim W van Egmond,Elvira R Flikweert,Martin J Heetveld,Johannes H Hegeman,Bernard G Schutte,Marijke C Trappenburg,Stijn C Voeten,Frans J G Wijdicks,Franka S Würdemann,Cornelis L P van de Ree, ,G De Klerk,C Stevens,J Snoek,H A F Luning,D Van der Velde,E J Verleisdonk,A H P Niggebrugge,M Regtuijt,F Wurdemann","doi":"10.1302/0301-620x.108b2.bjj-2025-0629.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0629.r1","url":null,"abstract":"AimsThis study examined the association between post-admission complications and 120-day mortality using data from a national hip fracture registry. A sub-analysis explored the impact of improved complication registration on these associations.MethodsWe conducted a cohort study including patients (1 January 2018 to 31 December 2023) from the Dutch Hip Fracture Audit (DHFA). Ten complications (anaemia, delirium, fall incident, heart failure, pneumonia, pressure ulcer, pulmonary embolism (PE), renal dysfunction, urinary tract infection, wound infection) were assessed. From 2018 to 2019, seven hospitals were recruited for additional data collection for the DHFA to improve and develop quality indicators. A multivariate Cox regression model was used to calculate the hazard ratio (HR) between complications and mortality at 30, 60, and 120 days. Subgroup analysis assessed the effect of better registration.ResultsA total of 86,524 patients were included, with a median age of 81 years (IQR 72 to 87). The overall complication rate was 25.7% (n = 22,210), anaemia was the most common complication (n = 8,027; 9.3%), followed by delirium (n = 7,836; 9.1%). In subgroup analysis, project hospitals had a higher overall complications rate (38.8% vs 27.4%; p < 0.001). After adjustment for confounders, at 30 days, heart failure (HR 2.45 (95% CI 2.15 to 2.75)), delirium (HR 1.28 (95% CI 1.19 to 1.38)), PE (HR 2.62 (95% CI 2.11 to 3.27)), renal dysfunction (HR 2.20 (95% CI 1.96 to 2.47)), and pneumonia (HR 2.35 (95% CI 2.15 to 2.56)) were significantly associated with an increased hazard of death. In the subgroup analysis, fewer complications were associated with an increased hazard of death in the project hospitals in comparison to the non-project hospitals.ConclusionFive complications were significantly associated with an increased risk of mortality at 30 and 60 days. These findings highlight the importance of closely monitoring and managing complications. Improved registration practices in project hospitals were linked to fewer complications that showed a relation with mortality. Complications without a clear association with mortality may be more suitable for short-cycle in-hospital feedback rather than a national audit.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"8 1","pages":"216-225"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-1438
Nick D Clement,Fares S Haddad
Robotic-assisted systems are being increasingly integrated into orthopaedic surgery, offering potential improvements in precision, reproducibility, and patient-reported outcome measures (PROMs) for unicompartmental knee arthroplasty (UKA), total knee arthroplasty (TKA), and total hip arthroplasty (THA). A review and summary of the early value assessment (EVA) undertaken by the National Institute for Health and Care Excellence (NICE) to evaluate the clinical effectiveness, cost-effectiveness, and implementation considerations of these technologies is presented. The EVA includes a review of the literature, an evidence gap analysis, and an evidence generation plan. Evidence from 28 studies and two registries suggested that robotic-assisted surgery was noninferior to conventional approaches in key outcomes, including PROMs, complications, hospital stay, and revisions, but it was associated with enhanced implant alignment. Short-term PROMs showed modest improvements, although most differences fell below currently defined clinically meaningful thresholds. Revision data were limited in follow-up, and ergonomic benefits for surgeons were uncertain. Economic evaluations suggested potential cost-effectiveness, particularly for THA, but assumptions regarding utilities, resource use, procedure volume, and implant costs introduced substantial uncertainty. The EVA highlighted the importance of training, equitable access, and national coordination for implementation. Evidence gaps were identified in long-term revision rates, health-related quality of life outcomes, productivity, sub-group effects, surgical team benefits, and learning curves. NICE recommended conditional adoption of six robotic platforms (ApolloKnee (Corin, UK), CORI (Smith & Nephew, UK), Mako (Stryker, USA), ROSA (Zimmer Biomet, USA), SkyWalker (MicroPort, China), and VELYS (DePuy Synthes, USA)) over a three-year evidence generation period, requiring annual reporting and adherence to regulatory standards. While robotic-assisted arthroplasty offers technical advantages, definitive clinical and economic benefits remain unproven. Surgeons, healthcare systems, and industry partners will need to work collaboratively to provide the required evidence in the next three years. A UK robotic registry could help address the evidence gaps more rapidly than individual centres by capturing large-scale national data.
{"title":"A review and summary of the National Institute for Health and Care Excellence early value assessment of robotic-assisted surgery for orthopaedic procedures.","authors":"Nick D Clement,Fares S Haddad","doi":"10.1302/0301-620x.108b2.bjj-2025-1438","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-1438","url":null,"abstract":"Robotic-assisted systems are being increasingly integrated into orthopaedic surgery, offering potential improvements in precision, reproducibility, and patient-reported outcome measures (PROMs) for unicompartmental knee arthroplasty (UKA), total knee arthroplasty (TKA), and total hip arthroplasty (THA). A review and summary of the early value assessment (EVA) undertaken by the National Institute for Health and Care Excellence (NICE) to evaluate the clinical effectiveness, cost-effectiveness, and implementation considerations of these technologies is presented. The EVA includes a review of the literature, an evidence gap analysis, and an evidence generation plan. Evidence from 28 studies and two registries suggested that robotic-assisted surgery was noninferior to conventional approaches in key outcomes, including PROMs, complications, hospital stay, and revisions, but it was associated with enhanced implant alignment. Short-term PROMs showed modest improvements, although most differences fell below currently defined clinically meaningful thresholds. Revision data were limited in follow-up, and ergonomic benefits for surgeons were uncertain. Economic evaluations suggested potential cost-effectiveness, particularly for THA, but assumptions regarding utilities, resource use, procedure volume, and implant costs introduced substantial uncertainty. The EVA highlighted the importance of training, equitable access, and national coordination for implementation. Evidence gaps were identified in long-term revision rates, health-related quality of life outcomes, productivity, sub-group effects, surgical team benefits, and learning curves. NICE recommended conditional adoption of six robotic platforms (ApolloKnee (Corin, UK), CORI (Smith & Nephew, UK), Mako (Stryker, USA), ROSA (Zimmer Biomet, USA), SkyWalker (MicroPort, China), and VELYS (DePuy Synthes, USA)) over a three-year evidence generation period, requiring annual reporting and adherence to regulatory standards. While robotic-assisted arthroplasty offers technical advantages, definitive clinical and economic benefits remain unproven. Surgeons, healthcare systems, and industry partners will need to work collaboratively to provide the required evidence in the next three years. A UK robotic registry could help address the evidence gaps more rapidly than individual centres by capturing large-scale national data.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"78 1","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0194.r2
Dan Moriwaki,Tomoyuki Nakasa,Yasunari Ikuta,Akinori Nekomoto,Shingo Kawabata,Satoru Sakurai,Saori Ishibashi,Nobuo Adachi
AimsThe cover of cartilaginous defects in patients with varus osteoarthritis (OA) of the ankle in the medial compartment (medial gutter, talar dome, and tibial plafond) after low tibial osteotomy has only been reported in a few studies. There has also been little description of the distribution of the defects and the risk factors for persistent defects after surgery. The aim of this study was to report the degree and distribution of cartilage repair after low tibial osteotomy, and their association with postoperative outcomes in these patients.MethodsWe retrospectively reviewed 24 patients (27 ankles) who underwent low tibial osteotomy for OA of the ankle. There were eight males and 16 females. Their mean age was 70.8 years (55 to 79), and the mean follow-up was 29.1 months (14 to 60). Clinical assessments included the Japanese Society for Surgery of the Foot (JSSF) ankle/hindfoot scale score and a visual analogue scale (VAS) score for pain. Radiological assessments included the Takakura-Tanaka classification, tibial anterior surface angle, talar tilt angle, tibiomedial malleolar angle (TMMA), tibial lateral surface angle, and mechanical ankle joint axis point. The condition of the cartilage was evaluated using the modified Outerbridge classification at the initial and second-look arthroscopies.ResultsThe mean JSSF scale and VAS sores and all radiological parameters improved significantly postoperatively. At the initial arthroscopy, grade 4 cartilage defects were most common in the medial gutter (26 of 27 ankles; 96%), followed by the anteromedial talar dome (talar zone 1) (20 of 27 ankles; 74%). At the second-look arthroscopy, grade 4 defects were absent in the medial gutter but remained in ten of 20 ankles (50%) of those initially in talar zone 1. The modified Outerbridge grade in talar zone 1 at second-look arthroscopy correlated positively with postoperative VAS (R = 0.48). Pre- and postoperative TMMA (cutoff values: 43.1° and 31.4°) and postoperative VAS scores were significantly higher in patients in whom there was not cartilage repair in talar zone 1 than in those in whom there was cartilage repair (preoperative TMMA, p = 0.004; postoperative TMMA, p = 0.015; postoperative VAS score, p = 0.026), while the postoperative mechanical ankle joint axis point (cutoff value: 80.7%) was significantly smaller (p = 0.041).ConclusionSecond-look arthroscopy after low tibial osteotomy revealed good cartilage repair in the medial gutter, but it was poor in the anteromedial talar dome and associated with persistent postoperative pain. A large pre- and postoperative TMMA and medial deviation of the postoperative axis of loading may inhibit cartilage repair in these patients.
目的:踝关节内翻性骨关节炎(OA)患者在胫骨下段截骨术后(内侧沟、距骨穹窿和胫骨平台)软骨缺损的修复,目前仅有少数研究报道。对缺损的分布和术后持续缺损的危险因素也很少有描述。本研究的目的是报道下胫截骨术后软骨修复的程度和分布,以及它们与这些患者术后预后的关系。方法回顾性分析24例(27踝关节)行胫骨下截骨治疗踝关节骨性关节炎的病例。其中男性8人,女性16人。平均年龄70.8岁(55 ~ 79岁),平均随访29.1个月(14 ~ 60岁)。临床评估包括日本足部外科学会(JSSF)踝关节/后足评分和视觉模拟评分(VAS)疼痛评分。影像学检查包括Takakura-Tanaka分型、胫骨前表面角、距骨倾斜角、胫骨内侧踝角(TMMA)、胫骨外侧表面角、机械踝关节轴点。在初次和二次关节镜检查时使用改良的Outerbridge分类评估软骨的状况。结果术后JSSF平均评分、VAS疮口及各项影像学指标均有明显改善。在最初的关节镜检查中,4级软骨缺损最常见于内侧沟(27个踝关节中有26个,96%),其次是距骨前内侧穹窿(距骨1区)(27个踝关节中有20个,74%)。在二次关节镜检查中,内侧沟没有4级缺损,但在距骨1区20个踝关节中仍有10个(50%)存在4级缺损。二次关节镜下距骨1区改良Outerbridge评分与术后VAS呈正相关(R = 0.48)。距骨1区无软骨修复组术前、术后TMMA(临界值分别为43.1°、31.4°)和术后VAS评分均明显高于有软骨修复组(术前TMMA, p = 0.004;术后TMMA, p = 0.015;术后VAS评分,p = 0.026),而术后机械踝关节轴点(临界值:80.7%)明显小于有软骨修复组(p = 0.041)。结论下胫截骨术后二次关节镜显示内侧沟软骨修复良好,距骨前内侧穹窿软骨修复较差,术后疼痛持续。在这些患者中,术前和术后较大的TMMA和术后负荷轴的内侧偏离可能会抑制软骨修复。
{"title":"Assessment of cartilage regeneration in initial and second-look arthroscopy following low tibial osteotomy for varus osteoarthritis of the ankle.","authors":"Dan Moriwaki,Tomoyuki Nakasa,Yasunari Ikuta,Akinori Nekomoto,Shingo Kawabata,Satoru Sakurai,Saori Ishibashi,Nobuo Adachi","doi":"10.1302/0301-620x.108b2.bjj-2025-0194.r2","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0194.r2","url":null,"abstract":"AimsThe cover of cartilaginous defects in patients with varus osteoarthritis (OA) of the ankle in the medial compartment (medial gutter, talar dome, and tibial plafond) after low tibial osteotomy has only been reported in a few studies. There has also been little description of the distribution of the defects and the risk factors for persistent defects after surgery. The aim of this study was to report the degree and distribution of cartilage repair after low tibial osteotomy, and their association with postoperative outcomes in these patients.MethodsWe retrospectively reviewed 24 patients (27 ankles) who underwent low tibial osteotomy for OA of the ankle. There were eight males and 16 females. Their mean age was 70.8 years (55 to 79), and the mean follow-up was 29.1 months (14 to 60). Clinical assessments included the Japanese Society for Surgery of the Foot (JSSF) ankle/hindfoot scale score and a visual analogue scale (VAS) score for pain. Radiological assessments included the Takakura-Tanaka classification, tibial anterior surface angle, talar tilt angle, tibiomedial malleolar angle (TMMA), tibial lateral surface angle, and mechanical ankle joint axis point. The condition of the cartilage was evaluated using the modified Outerbridge classification at the initial and second-look arthroscopies.ResultsThe mean JSSF scale and VAS sores and all radiological parameters improved significantly postoperatively. At the initial arthroscopy, grade 4 cartilage defects were most common in the medial gutter (26 of 27 ankles; 96%), followed by the anteromedial talar dome (talar zone 1) (20 of 27 ankles; 74%). At the second-look arthroscopy, grade 4 defects were absent in the medial gutter but remained in ten of 20 ankles (50%) of those initially in talar zone 1. The modified Outerbridge grade in talar zone 1 at second-look arthroscopy correlated positively with postoperative VAS (R = 0.48). Pre- and postoperative TMMA (cutoff values: 43.1° and 31.4°) and postoperative VAS scores were significantly higher in patients in whom there was not cartilage repair in talar zone 1 than in those in whom there was cartilage repair (preoperative TMMA, p = 0.004; postoperative TMMA, p = 0.015; postoperative VAS score, p = 0.026), while the postoperative mechanical ankle joint axis point (cutoff value: 80.7%) was significantly smaller (p = 0.041).ConclusionSecond-look arthroscopy after low tibial osteotomy revealed good cartilage repair in the medial gutter, but it was poor in the anteromedial talar dome and associated with persistent postoperative pain. A large pre- and postoperative TMMA and medial deviation of the postoperative axis of loading may inhibit cartilage repair in these patients.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"8 1","pages":"185-194"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0342.r1
Leming Mou,Jinwei Liu,Chuanhao Guo,Jing-Yu Zhang,Yancheng Liu,Xiaokang Gao,Deng-Xing Lun,Yongcheng Hu
AimsThis study evaluated the clinical outcome, complications, and overall efficacy of diaphyseal endoprosthetic reconstruction after tumour resection, with the aim of providing a comprehensive insight into the role of diaphyseal prostheses in managing segmental bone defects after resection of a bone tumour.MethodsA retrospective analysis was carried out of 112 patients treated at two centres. Resection length, intramedullary stem length, and fixation type were recorded. Clinical outcomes were assessed with Musculoskeletal Tumor Society (MSTS) scores, while survival rates were calculated using Kaplan-Meier analysis. Complications were classified according to the Henderson system.ResultsThe mean duration of follow-up was 27.2 months (3 to 159), the mean operating time 142.4 minutes (SD 44.1), and the mean blood loss 658.8 ml (SD 437.3). The mean resection length was 106.8 mm (SD 33.3), and the mean intramedullary stem length 96.1 mm (SD 34.1). Cemented fixation was used in 90.2% of cases (101 of 112), and auxiliary plates in 63.4% (71 of 112). The mean MSTS score was 24.3 (SD 3.3). Kaplan-Meier analysis revealed three-, five-, and ten-year survival rates of 42.9% (95% CI 33.4 to 55.1), 34.6% (95% CI 24.8 to 48.3), and 25.2% (95% CI 14.5 to 43.9) for patients, and 91.6% (95% CI 86.1 to 97.5), 82% (95% CI 69.4 to 96.8), and 82% (95% CI 69.4 to 96.8) for prostheses, respectively, with a significant difference between the two (p < 0.001). Medium- to long-term analysis showed that prosthesis survival, both for primary and metastatic tumours, exceeded patient survival. Additionally, cemented prostheses had significantly higher survival rates than uncemented prostheses (p = 0.006). Postoperative complications occurred in 16% of patients (18 of 112), with 6.3% (7 of 112) requiring reoperation.ConclusionDiaphyseal prostheses are a reliable solution for reconstructing segmental defects after resection of a bone tumour, with benefits such as early weightbearing, improved functional outcome, acceptable mid- to long-term failure rates, and effective local disease control for a variety of tumour types and anatomical locations.
目的本研究评估肿瘤切除后骨干假体内重建的临床结果、并发症和总体疗效,旨在全面了解骨干假体在骨肿瘤切除后治疗节段性骨缺损中的作用。方法对两个中心收治的112例患者进行回顾性分析。记录切除长度、髓内柄长度和固定方式。临床结果采用肌肉骨骼肿瘤学会(MSTS)评分评估,生存率采用Kaplan-Meier分析计算。根据亨德森系统对并发症进行分类。结果平均随访时间27.2个月(3 ~ 159),平均手术时间142.4 min (SD 44.1),平均出血量658.8 ml (SD 437.3)。平均切除长度为106.8 mm (SD 33.3),平均髓内茎长度为96.1 mm (SD 34.1)。90.2%的病例(112例中的101例)使用骨水泥固定,63.4%(112例中的71例)使用辅助钢板。MSTS平均评分为24.3 (SD 3.3)。Kaplan-Meier分析显示,患者的3年、5年和10年生存率分别为42.9% (95% CI 33.4至55.1)、34.6% (95% CI 24.8至48.3)和25.2% (95% CI 14.5至43.9),假体的生存率分别为91.6% (95% CI 86.1至97.5)、82% (95% CI 69.4至96.8)和82% (95% CI 69.4至96.8),两者之间存在显著差异(p < 0.001)。中长期分析表明,无论是原发性肿瘤还是转移性肿瘤,假体的生存期都超过了患者的生存期。此外,骨水泥假体的存活率明显高于非骨水泥假体(p = 0.006)。术后并发症发生率为16%(18 / 112),再次手术发生率为6.3%(7 / 112)。结论骨干假体是骨肿瘤切除术后重建节段性缺损的可靠方法,其优点包括早期负重、改善功能预后、可接受的中长期失败率以及对各种肿瘤类型和解剖位置的有效局部疾病控制。
{"title":"Endoprosthetic reconstruction of the diaphysis for segmental bone defects after bone tumour resection : a mid- and long-term retrospective study of 112 cases.","authors":"Leming Mou,Jinwei Liu,Chuanhao Guo,Jing-Yu Zhang,Yancheng Liu,Xiaokang Gao,Deng-Xing Lun,Yongcheng Hu","doi":"10.1302/0301-620x.108b2.bjj-2025-0342.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0342.r1","url":null,"abstract":"AimsThis study evaluated the clinical outcome, complications, and overall efficacy of diaphyseal endoprosthetic reconstruction after tumour resection, with the aim of providing a comprehensive insight into the role of diaphyseal prostheses in managing segmental bone defects after resection of a bone tumour.MethodsA retrospective analysis was carried out of 112 patients treated at two centres. Resection length, intramedullary stem length, and fixation type were recorded. Clinical outcomes were assessed with Musculoskeletal Tumor Society (MSTS) scores, while survival rates were calculated using Kaplan-Meier analysis. Complications were classified according to the Henderson system.ResultsThe mean duration of follow-up was 27.2 months (3 to 159), the mean operating time 142.4 minutes (SD 44.1), and the mean blood loss 658.8 ml (SD 437.3). The mean resection length was 106.8 mm (SD 33.3), and the mean intramedullary stem length 96.1 mm (SD 34.1). Cemented fixation was used in 90.2% of cases (101 of 112), and auxiliary plates in 63.4% (71 of 112). The mean MSTS score was 24.3 (SD 3.3). Kaplan-Meier analysis revealed three-, five-, and ten-year survival rates of 42.9% (95% CI 33.4 to 55.1), 34.6% (95% CI 24.8 to 48.3), and 25.2% (95% CI 14.5 to 43.9) for patients, and 91.6% (95% CI 86.1 to 97.5), 82% (95% CI 69.4 to 96.8), and 82% (95% CI 69.4 to 96.8) for prostheses, respectively, with a significant difference between the two (p < 0.001). Medium- to long-term analysis showed that prosthesis survival, both for primary and metastatic tumours, exceeded patient survival. Additionally, cemented prostheses had significantly higher survival rates than uncemented prostheses (p = 0.006). Postoperative complications occurred in 16% of patients (18 of 112), with 6.3% (7 of 112) requiring reoperation.ConclusionDiaphyseal prostheses are a reliable solution for reconstructing segmental defects after resection of a bone tumour, with benefits such as early weightbearing, improved functional outcome, acceptable mid- to long-term failure rates, and effective local disease control for a variety of tumour types and anatomical locations.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"3 1","pages":"241-250"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0975.r1
Matthew J Kennedy,Gopikrishnan Nair,Christopher McColm,Angus V Paterson,Phil J Walmsley,Nick D Clement,Jon V Clarke,Mark R J Jenkinson
AimsPolished taper slip (PTS) designs are widely used in cemented hip hemiarthroplasty for displaced intracapsular native hip fractures (NHFs), though concerns persist regarding PTS association with higher postoperative periprosthetic femoral fracture (POPFF) risk. The aim of this study was to evaluate the performance of the Exeter V40 cemented femoral component in the management of NHFs. This study prioritized evaluating survival, reoperations of the index hip joint, and major complications including intraoperative periprosthetic femoral fracture (IOPFF), POPFF, infection, and dislocation.MethodsThis retrospective cohort study included consecutive patients who underwent hip hemiarthroplasty with the Exeter V40 PTS femoral component for NHF at a single hospital between 1 February 2016 and 30 June 2024. Patient demographic details, time to theatre, surgical and medical management, American Society of Anesthesiologists grade, and mortality were collected. Reoperation and mortality were calculated to final follow-up. Cox regression analysis was performed to identify independent associations with revision or fixation adjusted for confounders.ResultsA total of 3,050 hip hemiarthroplasties in 2,948 patients were identified (69% female, median age 83 years (IQR 76 to 88)). Overall, 75 patients (2.5%) required reoperation, yielding a prosthesis-time incidence rate per 1,000 prosthesis-years (PTIR) of 10.7 (95% CI 8.4 to 13.4), with POPFF PTIR 5.1 per 1,000 prosthesis-years, infection PTIR 3.43 (95% CI 2.20 to 5.10), and dislocation PTIR 3.28 (95% CI 2.08 to 4.93). Male sex was an independent predictor of poor survival, with an adjusted hazard ratio of 2.85 (95% CI 1.76 to 4.60). Intraoperative fracture incidence was 0.9%, with the majority occurring at trial reduction (0.6%). Survival of the Exeter V40 femoral component was 97.6% (95% CI 96.9 to 98.4) at three years.ConclusionThe Exeter V40 femoral component demonstrates acceptable performance in hip hemiarthroplasty for NHF, with low rates of POPFF and femoral component revision. Male sex is an independent risk factor for reoperation of the index hip joint. Surgeons should exercise caution during trial reduction to minimize intraoperative fracture risk. These findings support its continued use in hip hemiarthroplasty for elderly patients.
目的:抛光锥形滑移(PTS)设计被广泛应用于骨水泥髋关节置换术治疗移位的囊内天然髋关节骨折(NHFs),尽管人们仍然担心PTS与术后较高的假体周围股骨骨折(POPFF)风险相关。本研究的目的是评估Exeter V40骨水泥股骨假体在治疗NHFs中的性能。本研究优先评估患者的生存率、髋关节再手术情况以及术中股骨假体周围骨折(IOPFF)、POPFF、感染和脱位等主要并发症。方法:本回顾性队列研究纳入了2016年2月1日至2024年6月30日在一家医院接受Exeter V40 PTS股骨假体半髋关节置换术治疗NHF的连续患者。收集患者的人口统计信息、到院时间、手术和医疗管理、美国麻醉医师学会分级和死亡率。计算再手术及死亡率至最终随访。进行Cox回归分析以确定校正或固定校正混杂因素的独立关联。结果2948例患者共行3050例髋关节半置换术(69%为女性,中位年龄83岁(IQR 76 ~ 88))。总体而言,75名患者(2.5%)需要再次手术,每1000个假体年的假体时间发生率(PTIR)为10.7 (95% CI 8.4至13.4),POPFF PTIR为5.1 / 1000个假体年,感染PTIR为3.43 (95% CI 2.20至5.10),脱位PTIR为3.28 (95% CI 2.08至4.93)。男性是生存率差的独立预测因子,校正后的危险比为2.85 (95% CI 1.76 ~ 4.60)。术中骨折发生率为0.9%,主要发生在试验复位时(0.6%)。Exeter V40股骨假体三年生存率为97.6% (95% CI 96.9 - 98.4)。结论Exeter V40股骨假体在治疗NHF的髋关节置换术中表现良好,其POPFF和股骨假体翻修率较低。男性是髋关节再手术的独立危险因素。外科医生在试验复位时应谨慎行事,以尽量减少术中骨折的风险。这些发现支持其继续用于老年患者的髋关节置换术。
{"title":"Survival of the Exeter V40 hemiarthroplasty femoral component and associated complications : an eight-year review of 3,050 cases from a major trauma centre.","authors":"Matthew J Kennedy,Gopikrishnan Nair,Christopher McColm,Angus V Paterson,Phil J Walmsley,Nick D Clement,Jon V Clarke,Mark R J Jenkinson","doi":"10.1302/0301-620x.108b2.bjj-2025-0975.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0975.r1","url":null,"abstract":"AimsPolished taper slip (PTS) designs are widely used in cemented hip hemiarthroplasty for displaced intracapsular native hip fractures (NHFs), though concerns persist regarding PTS association with higher postoperative periprosthetic femoral fracture (POPFF) risk. The aim of this study was to evaluate the performance of the Exeter V40 cemented femoral component in the management of NHFs. This study prioritized evaluating survival, reoperations of the index hip joint, and major complications including intraoperative periprosthetic femoral fracture (IOPFF), POPFF, infection, and dislocation.MethodsThis retrospective cohort study included consecutive patients who underwent hip hemiarthroplasty with the Exeter V40 PTS femoral component for NHF at a single hospital between 1 February 2016 and 30 June 2024. Patient demographic details, time to theatre, surgical and medical management, American Society of Anesthesiologists grade, and mortality were collected. Reoperation and mortality were calculated to final follow-up. Cox regression analysis was performed to identify independent associations with revision or fixation adjusted for confounders.ResultsA total of 3,050 hip hemiarthroplasties in 2,948 patients were identified (69% female, median age 83 years (IQR 76 to 88)). Overall, 75 patients (2.5%) required reoperation, yielding a prosthesis-time incidence rate per 1,000 prosthesis-years (PTIR) of 10.7 (95% CI 8.4 to 13.4), with POPFF PTIR 5.1 per 1,000 prosthesis-years, infection PTIR 3.43 (95% CI 2.20 to 5.10), and dislocation PTIR 3.28 (95% CI 2.08 to 4.93). Male sex was an independent predictor of poor survival, with an adjusted hazard ratio of 2.85 (95% CI 1.76 to 4.60). Intraoperative fracture incidence was 0.9%, with the majority occurring at trial reduction (0.6%). Survival of the Exeter V40 femoral component was 97.6% (95% CI 96.9 to 98.4) at three years.ConclusionThe Exeter V40 femoral component demonstrates acceptable performance in hip hemiarthroplasty for NHF, with low rates of POPFF and femoral component revision. Male sex is an independent risk factor for reoperation of the index hip joint. Surgeons should exercise caution during trial reduction to minimize intraoperative fracture risk. These findings support its continued use in hip hemiarthroplasty for elderly patients.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"42 1","pages":"226-233"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0106.r1
Michael S Ramos,Brian Benyamini,Varun Kompala,Shujaa T Khan,Kyle N Kunze,Anabelle Visperas,Peter A Surace,Nicolas S Piuzzi
AimsThe aim of this study was to evaluate the overall mortality rate in patients with periprosthetic joint infection (PJI) after total knee arthroplasty (TKA), the overall mortality over time, and mortality after treatment.MethodsOvid MEDLINE, Embase, CINAHL, Cochrane Library, Scopus, and Web of Science, were searched for studies reporting the rate of mortality in patients with TKA PJI until December 2023. Full-length studies with extractable data dealing with mortality in these patients were included. Studies were excluded if they involved TKAs which were undertaken for oncological or traumatic indications or septic arthritis, or were partial or revision TKAs. Studies in which primarily high-risk patients, such those with an organ transplant or cancer, were also excluded, in order to allow the mortality rate in patients with PJI after TKA in routine clinical practice to be evaluated. Data were abstracted using a standardized form. Meta-analyses of the proportions with random-effects estimators were used to report the mortality rate after TKA PJI, over time, and after treatment. The study adhered to the 2020 PRISMA guidelines.ResultsA total of 83,353 patients with a PJI after TKA from 39 studies were included. At a mean follow-up of 4.4 years (1 month to 17 years), the overall mortality rate after TKA PJI was 13.3% (95% CI 8.8 to 18.5). It was 4.8% (1.2 to 18.0), 7.0% (2.2 to 29.9), and 6.4% (3.0 to 46.0) at three, 12, and 24 months, respectively. The rate significantly differed between the different forms of surgical treatment for PJI (p < 0.001): debridement, antibiotics, and implant retention (DAIR) 12.3% (95% CI 3.9 to 24.0); one-stage exchange arthroplasty 0.47% (95% CI 0 to 1.5); and two-stage exchange arthroplasty 11.5% (95% CI 8.5 to 15.0). There were no significant differences in the mortality rate between patients treated with DAIR and those who underwent a two-stage exchange arthroplasty at three and 12 months.ConclusionMortality after TKA PJI remains high, surpassing the five-year rates of mortality in patients with cancer of the breast and prostate. The burden associated with PJI necessitates a multidisciplinary approach and dedicated funding to improve patient care, address this critical issue generally, and reduce mortality.
目的本研究的目的是评估全膝关节置换术(TKA)后假体周围关节感染(PJI)患者的总死亡率、随时间的总死亡率和治疗后的死亡率。方法检索MEDLINE、Embase、CINAHL、Cochrane Library、Scopus和Web of Science,检索截至2023年12月报道TKA PJI患者死亡率的研究。纳入了涉及这些患者死亡率的具有可提取数据的完整研究。如果研究涉及肿瘤或创伤指征或脓毒性关节炎的tka,或部分或改进型tka,则排除研究。为了评估常规临床实践中TKA后PJI患者的死亡率,还排除了主要高风险患者(如器官移植或癌症患者)的研究。数据用标准化的形式抽象出来。采用随机效应估计器对比例进行荟萃分析,报告TKA - PJI术后、随时间和治疗后的死亡率。该研究遵循了2020年PRISMA指南。结果39项研究共纳入TKA后PJI患者83353例。平均随访4.4年(1个月至17年),TKA PJI术后总死亡率为13.3% (95% CI 8.8至18.5)。3个月、12个月、24个月分别为4.8%(1.2 ~ 18.0)、7.0%(2.2 ~ 29.9)、6.4%(3.0 ~ 46.0)。不同形式的PJI手术治疗之间的比例差异显著(p < 0.001):清创、抗生素和种植体保留(DAIR) 12.3% (95% CI 3.9 ~ 24.0);一期置换关节置换术0.47% (95% CI 0 ~ 1.5);两期置换关节置换术11.5% (95% CI 8.5 ~ 15.0)。在3个月和12个月时,接受DAIR治疗的患者和接受两期置换关节置换术的患者之间的死亡率没有显著差异。结论TKA PJI术后的死亡率仍然很高,超过乳腺癌和前列腺癌患者的5年死亡率。与PJI相关的负担需要多学科方法和专门资金来改善患者护理,普遍解决这一关键问题,并降低死亡率。
{"title":"Mortality after an infected total knee arthroplasty : a meta-analysis.","authors":"Michael S Ramos,Brian Benyamini,Varun Kompala,Shujaa T Khan,Kyle N Kunze,Anabelle Visperas,Peter A Surace,Nicolas S Piuzzi","doi":"10.1302/0301-620x.108b2.bjj-2025-0106.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0106.r1","url":null,"abstract":"AimsThe aim of this study was to evaluate the overall mortality rate in patients with periprosthetic joint infection (PJI) after total knee arthroplasty (TKA), the overall mortality over time, and mortality after treatment.MethodsOvid MEDLINE, Embase, CINAHL, Cochrane Library, Scopus, and Web of Science, were searched for studies reporting the rate of mortality in patients with TKA PJI until December 2023. Full-length studies with extractable data dealing with mortality in these patients were included. Studies were excluded if they involved TKAs which were undertaken for oncological or traumatic indications or septic arthritis, or were partial or revision TKAs. Studies in which primarily high-risk patients, such those with an organ transplant or cancer, were also excluded, in order to allow the mortality rate in patients with PJI after TKA in routine clinical practice to be evaluated. Data were abstracted using a standardized form. Meta-analyses of the proportions with random-effects estimators were used to report the mortality rate after TKA PJI, over time, and after treatment. The study adhered to the 2020 PRISMA guidelines.ResultsA total of 83,353 patients with a PJI after TKA from 39 studies were included. At a mean follow-up of 4.4 years (1 month to 17 years), the overall mortality rate after TKA PJI was 13.3% (95% CI 8.8 to 18.5). It was 4.8% (1.2 to 18.0), 7.0% (2.2 to 29.9), and 6.4% (3.0 to 46.0) at three, 12, and 24 months, respectively. The rate significantly differed between the different forms of surgical treatment for PJI (p < 0.001): debridement, antibiotics, and implant retention (DAIR) 12.3% (95% CI 3.9 to 24.0); one-stage exchange arthroplasty 0.47% (95% CI 0 to 1.5); and two-stage exchange arthroplasty 11.5% (95% CI 8.5 to 15.0). There were no significant differences in the mortality rate between patients treated with DAIR and those who underwent a two-stage exchange arthroplasty at three and 12 months.ConclusionMortality after TKA PJI remains high, surpassing the five-year rates of mortality in patients with cancer of the breast and prostate. The burden associated with PJI necessitates a multidisciplinary approach and dedicated funding to improve patient care, address this critical issue generally, and reduce mortality.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"93 1","pages":"177-184"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2025-0277.r1
Hillary Brenda Nguyen,Patricia E Miller,Nicholas Sullivan,Susan T Mahan,Samantha A Spencer,James R Kasser,Matthew Milewski,Dennis Kramer,Collin J May
AimsThe Patient-Reported Outcomes Measurement Information System (PROMIS) has not been broadly validated for use in paediatric patients with lower limb musculoskeletal conditions. The aim of this study was to evaluate the psychometric properties of PROMIS administered using computerized adaptive testing.MethodsThis was a single-centre prospective study involving consecutive patients, aged between 11 and 17 years, with orthopaedic conditions affecting the lower limbs. The convergent and divergent construct validity of PROMIS domains with corresponding subscales of the Paediatric Outcomes Data Collection Instrument (PODCI) were assessed in Group A. The reliability was assessed by retesting a sub-group (Group B) of patients from Group A with the same PROMIS domains in those whose condition was not expected to vary within a month of their initial assessment. PROMIS domain responses preoperatively, and > six months postoperatively, were assessed in Group C.ResultsThe construct validity was assessed in 280 patients in Group A, and convergent validity was achieved between the PROMIS and PODCI Mobility domains (r = 0.73; p < 0.001), Upper Extremity domains (r = 0.52; p < 0.001), PROMIS Physical Activity domain and PODCI Sports and Physical Function subscale (r = 0.57; p < 0.001), PROMIS Depressive Symptoms domain and PODCI Happiness subscale (r = -0.54; p < 0.001), and PROMIS Pain domain and PODCI Pain/Comfort subscale (r = -0.71; p < 0.001). Divergent validity criteria were met with a correlation of < 0.30. The median number of questions required to answer on PROMIS was less than on PODCI. Reliability was assessed in 51 patients in Group B, in whom the PROMIS domains were collected again following a mean of 20 days. Test-retest reliability was highest for Mobility (intraclass correlation coefficient (ICC) = 0.84), Depressive Symptoms (ICC = 0.75), and Pain (ICC = 0.74). Responsiveness was assessed in 150 patients in Group C in whom PROMIS domains were collected preoperatively and at a mean of ten months postoperatively. The largest effect sizes were seen in the Pain and Mobility domains, with smaller improvements in the Physical Activity, Depressive Symptoms, and Upper Extremity domains.ConclusionPROMIS domains of Mobility, Physical Activity, Depressive Symptoms, and Pain may be useful for assessing patient-reported health status in paediatric patients with lower limb orthopaedic conditions.
患者报告的结果测量信息系统(PROMIS)尚未被广泛验证用于患有下肢肌肉骨骼疾病的儿科患者。本研究的目的是评估使用计算机自适应测试的PROMIS管理的心理测量特性。方法:这是一项单中心前瞻性研究,涉及年龄在11至17岁之间的连续患者,患有影响下肢的骨科疾病。a组采用儿科结局数据收集工具(PODCI)相应子量表对PROMIS域的收敛性和发散性结构效度进行评估。通过重新测试a组中具有相同PROMIS域的患者的亚组(B组)来评估可靠性,这些患者的病情在首次评估后一个月内预计不会发生变化。结果A组280例患者进行了结构效度评估,在PROMIS和PODCI活动域(r = 0.73, p < 0.001)、上肢域(r = 0.52, p < 0.001)、PROMIS体力活动域和PODCI运动和身体功能子量表(r = 0.57, p < 0.001)之间达到了收敛效度;p < 0.001)、PROMIS抑郁症状域和PODCI快乐子量表(r = -0.54; p < 0.001)、PROMIS疼痛域和PODCI疼痛/舒适子量表(r = -0.71; p < 0.001)。符合发散效度标准,相关系数< 0.30。在PROMIS上需要回答的问题中位数比在PODCI上要少。对B组的51例患者进行可靠性评估,这些患者在平均20天后再次收集PROMIS域。运动能力(类内相关系数(ICC) = 0.84)、抑郁症状(ICC = 0.75)和疼痛(ICC = 0.74)的重测信度最高。对C组150例患者的反应性进行评估,这些患者术前和术后平均10个月收集PROMIS域。最大的效应量出现在疼痛和活动领域,在体力活动、抑郁症状和上肢领域有较小的改善。结论promis的活动能力、身体活动、抑郁症状和疼痛领域可能有助于评估患有下肢骨科疾病的儿科患者的健康状况。
{"title":"Psychometric evaluation of Patient-Reported Outcome Measurement Information System (PROMIS) measures in children and adolescents with lower limb orthopaedic conditions : construct validity, reliability, and responsiveness.","authors":"Hillary Brenda Nguyen,Patricia E Miller,Nicholas Sullivan,Susan T Mahan,Samantha A Spencer,James R Kasser,Matthew Milewski,Dennis Kramer,Collin J May","doi":"10.1302/0301-620x.108b2.bjj-2025-0277.r1","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2025-0277.r1","url":null,"abstract":"AimsThe Patient-Reported Outcomes Measurement Information System (PROMIS) has not been broadly validated for use in paediatric patients with lower limb musculoskeletal conditions. The aim of this study was to evaluate the psychometric properties of PROMIS administered using computerized adaptive testing.MethodsThis was a single-centre prospective study involving consecutive patients, aged between 11 and 17 years, with orthopaedic conditions affecting the lower limbs. The convergent and divergent construct validity of PROMIS domains with corresponding subscales of the Paediatric Outcomes Data Collection Instrument (PODCI) were assessed in Group A. The reliability was assessed by retesting a sub-group (Group B) of patients from Group A with the same PROMIS domains in those whose condition was not expected to vary within a month of their initial assessment. PROMIS domain responses preoperatively, and > six months postoperatively, were assessed in Group C.ResultsThe construct validity was assessed in 280 patients in Group A, and convergent validity was achieved between the PROMIS and PODCI Mobility domains (r = 0.73; p < 0.001), Upper Extremity domains (r = 0.52; p < 0.001), PROMIS Physical Activity domain and PODCI Sports and Physical Function subscale (r = 0.57; p < 0.001), PROMIS Depressive Symptoms domain and PODCI Happiness subscale (r = -0.54; p < 0.001), and PROMIS Pain domain and PODCI Pain/Comfort subscale (r = -0.71; p < 0.001). Divergent validity criteria were met with a correlation of < 0.30. The median number of questions required to answer on PROMIS was less than on PODCI. Reliability was assessed in 51 patients in Group B, in whom the PROMIS domains were collected again following a mean of 20 days. Test-retest reliability was highest for Mobility (intraclass correlation coefficient (ICC) = 0.84), Depressive Symptoms (ICC = 0.75), and Pain (ICC = 0.74). Responsiveness was assessed in 150 patients in Group C in whom PROMIS domains were collected preoperatively and at a mean of ten months postoperatively. The largest effect sizes were seen in the Pain and Mobility domains, with smaller improvements in the Physical Activity, Depressive Symptoms, and Upper Extremity domains.ConclusionPROMIS domains of Mobility, Physical Activity, Depressive Symptoms, and Pain may be useful for assessing patient-reported health status in paediatric patients with lower limb orthopaedic conditions.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"52 1","pages":"259-266"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01DOI: 10.1302/0301-620x.108b2.bjj-2024-1632.r3
Jody Law,Jeffrey Yao
The surgical treatment of carpometacarpal (CMC) arthritis of the thumb is widely performed, and provides good pain relief and restoration of function. This condition may be successfully treated using one of many surgical procedures. While the incidence of failure following these procedures is low, potential complications include persistent pain, deformity, and weakness. Identifying the cause of persistent symptoms requires a careful and methodical approach. This review aims to highlight the common reasons for failure, provide a comprehensive discussion of the literature surrounding failed surgical treatment of CMC arthritis of the thumb, and offer a detailed, algorithmic approach to the diagnosis and treatment of this condition.
{"title":"Diagnosis and treatment of failed surgical treatment of carpometacarpal joint arthritis of the thumb.","authors":"Jody Law,Jeffrey Yao","doi":"10.1302/0301-620x.108b2.bjj-2024-1632.r3","DOIUrl":"https://doi.org/10.1302/0301-620x.108b2.bjj-2024-1632.r3","url":null,"abstract":"The surgical treatment of carpometacarpal (CMC) arthritis of the thumb is widely performed, and provides good pain relief and restoration of function. This condition may be successfully treated using one of many surgical procedures. While the incidence of failure following these procedures is low, potential complications include persistent pain, deformity, and weakness. Identifying the cause of persistent symptoms requires a careful and methodical approach. This review aims to highlight the common reasons for failure, provide a comprehensive discussion of the literature surrounding failed surgical treatment of CMC arthritis of the thumb, and offer a detailed, algorithmic approach to the diagnosis and treatment of this condition.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"58 1","pages":"153-159"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}