晚期卵巢癌的微观成本分析:从巴西一家参考公立医院的角度看现实世界的证据

IF 1.4 Q3 HEALTH CARE SCIENCES & SERVICES Value in health regional issues Pub Date : 2024-05-06 DOI:10.1016/j.vhri.2024.100999
Carolina Martins BPharm , Raquelaine Padilha BSN, MSc , Lucas Okumura BPharm, MSc , Andreia Melo MD, MSc, PhD , Rodrigo Costa BPharm, PhD
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引用次数: 0

摘要

目的 从巴西一家参考公立医院的角度,基于真实世界的证据,使用微观成本计算技术评估晚期卵巢癌的成本。方法 对2017年新诊断为晚期卵巢癌并随访长达5年的患者进行回顾性队列研究。采用自下而上的微观成本计算方法,使用基于活动的成本法,根据患者整个治疗过程中的活动消耗评估服务成本。结果结果显示,患者的中位总生存期为 35.3 个月,中位年龄为 57 岁(33-80 岁)。每位患者在 35.3 个月期间的平均费用为 34 991.595 美元,其中因疾病进展和临终关怀而入院的费用最高。结论结果表明,目前治疗晚期卵巢癌的活动成本对公共卫生系统产生了重要的经济影响。这些数据有助于今后分析采用新技术治疗卵巢癌的影响以及巴西公共医疗系统的融资和可持续性。
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Microcosting Analysis of Advanced Ovarian Cancer: Real-World Evidence From the Perspective of a Reference Public Brazilian Hospital

Objectives

Evaluate the cost of advanced ovarian cancer, using the microcosting technique, based on real-world evidence from the perspective of a reference Brazilian public hospital.

Methods

Retrospective cohort study of patients newly diagnosed with advanced ovarian cancer in 2017 and followed-up for up to 5 years. A bottom-up microcosting method was applied, using the activity-based cost approach, which evaluates service costs based on activity consumption throughout patients’ journey.

Results

The results indicate a median overall survival of 35.3 months and a median age of 57 years (33-80 years old). The average cost per patient was USD 34 991.595 over a period of 35.3 months, with admissions because of the disease progression and end-of-life care being the most relevant.

Conclusions

The results show that the costs of activities currently involved in the treatment of advanced ovarian cancer represent an important economic impact for the public health system. These data can support future analyses on the impact of incorporating new technologies for the treatment of ovarian cancer and on the financing and sustainability of the Brazilian public healthcare system.

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来源期刊
Value in health regional issues
Value in health regional issues Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
2.60
自引率
5.00%
发文量
127
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