{"title":"及时血液透析成功治疗一名年轻女性急性水杨酸盐过量 - 病例报告。","authors":"Amitabh Kulkarni, Pavan Shrivastava, Rajesh Kumar Phulara","doi":"10.4103/ijn.ijn_141_22","DOIUrl":null,"url":null,"abstract":"<p><p>Salicylates are often used in clinical practice as antiplatelets as well as analgesics. Its overdose is not uncommon due to its easy availability over the counter. Mortality is high in severe cases when a lethal dose is consumed. Treatment of overdose is difficult due to the non-availability of an antidote. Hemodialysis is an underutilized treatment modality in such cases. We discuss here a case of a young female who presented to us 2.5 h after the consumption of a lethal dose of salicylate with symptoms of only tinnitus. She was successfully treated with two sessions of hemodialysis. Her drug levels on admission were remarkably high, and early hemodialysis was justified in view of high-dose consumption with minimal symptoms.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"34 1","pages":"67-69"},"PeriodicalIF":0.8000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003594/pdf/","citationCount":"0","resultStr":"{\"title\":\"Timely Hemodialysis for Successful Treatment of Acute Salicylate Overdose in a Young Adult Female - A Case Report.\",\"authors\":\"Amitabh Kulkarni, Pavan Shrivastava, Rajesh Kumar Phulara\",\"doi\":\"10.4103/ijn.ijn_141_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Salicylates are often used in clinical practice as antiplatelets as well as analgesics. Its overdose is not uncommon due to its easy availability over the counter. Mortality is high in severe cases when a lethal dose is consumed. Treatment of overdose is difficult due to the non-availability of an antidote. Hemodialysis is an underutilized treatment modality in such cases. We discuss here a case of a young female who presented to us 2.5 h after the consumption of a lethal dose of salicylate with symptoms of only tinnitus. She was successfully treated with two sessions of hemodialysis. Her drug levels on admission were remarkably high, and early hemodialysis was justified in view of high-dose consumption with minimal symptoms.</p>\",\"PeriodicalId\":13359,\"journal\":{\"name\":\"Indian Journal of Nephrology\",\"volume\":\"34 1\",\"pages\":\"67-69\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003594/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Nephrology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ijn.ijn_141_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/2/21 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Nephrology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijn.ijn_141_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/2/21 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Timely Hemodialysis for Successful Treatment of Acute Salicylate Overdose in a Young Adult Female - A Case Report.
Salicylates are often used in clinical practice as antiplatelets as well as analgesics. Its overdose is not uncommon due to its easy availability over the counter. Mortality is high in severe cases when a lethal dose is consumed. Treatment of overdose is difficult due to the non-availability of an antidote. Hemodialysis is an underutilized treatment modality in such cases. We discuss here a case of a young female who presented to us 2.5 h after the consumption of a lethal dose of salicylate with symptoms of only tinnitus. She was successfully treated with two sessions of hemodialysis. Her drug levels on admission were remarkably high, and early hemodialysis was justified in view of high-dose consumption with minimal symptoms.