自发性颅内低血压的诊断和治疗:硬膜外补血的作用。

IF 2.3 Q3 CLINICAL NEUROLOGY Neurology. Clinical practice Pub Date : 2024-06-01 Epub Date: 2024-04-30 DOI:10.1212/CPJ.0000000000200290
Andrew L Callen, Deborah I Friedman, Simy Parikh, Jill C Rau, Wouter I Schievink, Jeremy K Cutsforth-Gregory, Timothy J Amrhein, Elena Haight, Robert P Cowan, Meredith J Barad, Jennifer M Hah, Tracy Jackson, Connie Deline, Andrea J Buchanan, Ian Carroll
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引用次数: 0

摘要

综述的目的:本综述重点探讨了诊断和治疗自发性颅内低血压(SIH)的挑战,这是一种由脊髓CSF渗漏引起的疾病。它强调了提高认识的必要性,并提倡在疑似病例中尽早、周到地使用经验性硬膜外血贴(EBPs):SIH 的诊断因症状多变和成像结果不一致(包括脑部 MRI 正常和脊柱开口压力不可靠)而受到阻碍。在鉴别诊断中考虑 SIH 至关重要,尤其是结缔组织疾病患者。早期 EBP 干预可改善预后。摘要:SIH 的诊断和治疗仍然不足,需要加强认识和理解。本综述提倡在处理疑似 SIH 时积极使用 EBP,并呼吁继续开展研究以推进诊断和治疗方法,同时强调需要创新的成像技术来进行准确诊断和及时干预。
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Diagnosis and Treatment of Spontaneous Intracranial Hypotension: Role of Epidural Blood Patching.

Purpose of review: This review focuses on the challenges of diagnosing and treating spontaneous intracranial hypotension (SIH), a condition caused by spinal CSF leakage. It emphasizes the need for increased awareness and advocates for early and thoughtful use of empirical epidural blood patches (EBPs) in suspected cases.

Recent findings: SIH diagnosis is hindered by variable symptoms and inconsistent imaging results, including normal brain MRI and unreliable spinal opening pressures. It is crucial to consider SIH in differential diagnoses, especially in patients with connective tissue disorders. Early EBP intervention is shown to improve outcomes.

Summary: SIH remains underdiagnosed and undertreated, requiring heightened awareness and understanding. This review promotes proactive EBP use in managing suspected SIH and calls for continued research to advance diagnostic and treatment methods, emphasizing the need for innovative imaging techniques for accurate diagnosis and timely intervention.

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来源期刊
Neurology. Clinical practice
Neurology. Clinical practice CLINICAL NEUROLOGY-
CiteScore
4.00
自引率
0.00%
发文量
77
期刊介绍: Neurology® Genetics is an online open access journal publishing peer-reviewed reports in the field of neurogenetics. The journal publishes original articles in all areas of neurogenetics including rare and common genetic variations, genotype-phenotype correlations, outlier phenotypes as a result of mutations in known disease genes, and genetic variations with a putative link to diseases. Articles include studies reporting on genetic disease risk, pharmacogenomics, and results of gene-based clinical trials (viral, ASO, etc.). Genetically engineered model systems are not a primary focus of Neurology® Genetics, but studies using model systems for treatment trials, including well-powered studies reporting negative results, are welcome.
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