Daniela de la Rosa-Zamboni, Mónica Villa-Guillén, Anaíd Bustos-Hamdan, María Isabel Rosas-Mateos, Marisol Medina-Pelcastre, Margarita Torres-García, María Isabel Franco-Hernández, María Del Carmen Castellanos-Cruz, Israel Parra-Ortega, Edmedt Fest-Parra, María Citlalli Casillas-Casillas, Ana Carmen Guerrero-Díaz
{"title":"紫外线-C 消毒和镀铜对 ESBL 感染率较高的新生儿重症监护室医护人员相关感染的影响。","authors":"Daniela de la Rosa-Zamboni, Mónica Villa-Guillén, Anaíd Bustos-Hamdan, María Isabel Rosas-Mateos, Marisol Medina-Pelcastre, Margarita Torres-García, María Isabel Franco-Hernández, María Del Carmen Castellanos-Cruz, Israel Parra-Ortega, Edmedt Fest-Parra, María Citlalli Casillas-Casillas, Ana Carmen Guerrero-Díaz","doi":"10.1016/j.eimce.2024.02.014","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.</p><p><strong>Methods: </strong>All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1+UV-C disinfection; P3: P2+Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.</p><p><strong>Results: </strong>552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (p=0.006). HCAIs with bacterial isolates dropped from 5.39/1000 PD in PI to 1.79/1000 PD in P4 (p=0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI<sub>95%</sub> 0.30-0.81, p=0.005) and with lesser HCAIs with bacterial isolates (RR 0.33, CI<sub>95%</sub> 0.14-0.77, p=0.011).</p><p><strong>Conclusions: </strong>Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections.\",\"authors\":\"Daniela de la Rosa-Zamboni, Mónica Villa-Guillén, Anaíd Bustos-Hamdan, María Isabel Rosas-Mateos, Marisol Medina-Pelcastre, Margarita Torres-García, María Isabel Franco-Hernández, María Del Carmen Castellanos-Cruz, Israel Parra-Ortega, Edmedt Fest-Parra, María Citlalli Casillas-Casillas, Ana Carmen Guerrero-Díaz\",\"doi\":\"10.1016/j.eimce.2024.02.014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.</p><p><strong>Methods: </strong>All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1+UV-C disinfection; P3: P2+Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.</p><p><strong>Results: </strong>552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (p=0.006). HCAIs with bacterial isolates dropped from 5.39/1000 PD in PI to 1.79/1000 PD in P4 (p=0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI<sub>95%</sub> 0.30-0.81, p=0.005) and with lesser HCAIs with bacterial isolates (RR 0.33, CI<sub>95%</sub> 0.14-0.77, p=0.011).</p><p><strong>Conclusions: </strong>Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.</p>\",\"PeriodicalId\":72916,\"journal\":{\"name\":\"Enfermedades infecciosas y microbiologia clinica (English ed.)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Enfermedades infecciosas y microbiologia clinica (English ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.eimce.2024.02.014\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Enfermedades infecciosas y microbiologia clinica (English ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.eimce.2024.02.014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections.
Introduction: Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.
Methods: All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1+UV-C disinfection; P3: P2+Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.
Results: 552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (p=0.006). HCAIs with bacterial isolates dropped from 5.39/1000 PD in PI to 1.79/1000 PD in P4 (p=0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI95% 0.30-0.81, p=0.005) and with lesser HCAIs with bacterial isolates (RR 0.33, CI95% 0.14-0.77, p=0.011).
Conclusions: Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.